V
Vadim A. Soloshonok
Researcher at University of the Basque Country
Publications - 417
Citations - 16252
Vadim A. Soloshonok is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 64, co-authored 406 publications receiving 14170 citations. Previous affiliations of Vadim A. Soloshonok include University of Oklahoma & Centre national de la recherche scientifique.
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Journal ArticleDOI
Biocatalytic Approach to Enantiomerically Pure β-Amino Acids.
Vadim A. Soloshonok,Nataly A. Fokina,A. V. Rybakova,I.P. Shishkina,S. V. Galushko,Alexander E. Sorochinsky,Valery P. Kukhar,Mariya V. Savchenko,Vytas K. Švedas +8 more
TL;DR: In this article, β-Aryl-β-amino acids were prepared in good chemical yield and high enantiomeric purity via penicillin acylase-catalyzed hydrolysis of the corresponding N-phenylacetyl derivatives.
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Practical Synthesis of Fluorine-Containing α- and β-Amino Acids: Recipes from Kiev, Ukraine
TL;DR: In this article, the authors present a review of various synthetic methods, developed by the Kiev's school of bioorganic chemistry, for the preparation of fluorine-containing analogs of α- and β-amino acids, α-hydroxy acids, amines, as well as their phosphorus and sulfur-derived compounds, in enantiomerically pure form.
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Unusual Condensation of 1,1,1,5,5,5-Hexafluoropentane-2,4-dione with (R)-Phenylglycinol.
TL;DR: In this article, the reaction of 1.1, 1,1,1-5,5, 5,5-hexafluoropentane-2,4-dione with (R )-phenylglycinol proceeds via the intermediate formation of ( R,4 E,6 Z )-5.7-bis(trifluoromethyl)-2,3-dihydro-3-pyridine, which further undergoes a base-catalysed 1,3proton shift followed by [1,2
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Concise and Scalable Asymmetric Synthesis of 5‐(1‐Amino‐2,2,2‐trifluoroethyl)thiazolo[3,2‐b][1,2,4]triazoles.
TL;DR: The asymmetric Mannich-type addition between C5-lithiated heterocycles (I) and enantiopure aldimine (II) is described in this article.
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A Convenient, Room‐Temperature — Organic Base Protocol for Preparing Chiral 3‐(Enoyl)‐1,3‐oxazolidin‐2‐ones.
TL;DR: In this paper, the authors developed a new protocol for the preparation of chiral 3-enoyl]-1,3-oxazolidin-2-ones under the ultimately simple reaction conditions starting with the corresponding enoyl chlorides and 1,3oxozolidin 2-ones with Et3N/LiCl at room temperature.