V
Vadim A. Soloshonok
Researcher at University of the Basque Country
Publications - 417
Citations - 16252
Vadim A. Soloshonok is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 64, co-authored 406 publications receiving 14170 citations. Previous affiliations of Vadim A. Soloshonok include University of Oklahoma & Centre national de la recherche scientifique.
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Journal ArticleDOI
The self-disproportionation of enantiomers (SDE): a menace or an opportunity?
Jianlin Han,Osamu Kitagawa,Alicja Wzorek,Karel D. Klika,Vadim A. Soloshonok,Vadim A. Soloshonok +5 more
TL;DR: The self-disproportionation of enantiomers (SDE) is reported on: the spontaneous fractionation of scalemic material into enantioenriched and -depleted fractions when any physicochemical process is applied.
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Optical purifications via self-disproportionation of enantiomers by achiral chromatography: case study of a series of α-CF3-containing secondary alcohols.
Alexander E. Sorochinsky,Alexander E. Sorochinsky,Toshimasa Katagiri,Taizo Ono,Alicja Wzorek,José Luis Aceña,Vadim A. Soloshonok,Vadim A. Soloshonok +7 more
TL;DR: This work demonstrates that self-disproportionation of enantiomers via achiral chromatography can be recommended as inexpensive and general method for optical purification of enantomerically enriched compounds.
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Michael addition reactions between chiral equivalents of a nucleophilic glycine and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general method for efficient preparation of β-substituted pyroglutamic acids. Case of topographically controlled stereoselectivity
Vadim A. Soloshonok,Chaozhong Cai,Takeshi Yamada,Hisanori Ueki,Yasufumi Ohfune,Victor J. Hruby +5 more
TL;DR: Excellent chemical and stereochemical yields are rendered, combined with the simplicity and operational convenience of the experimental procedures, render the present method of immediate use for preparing various beta-substituted pyroglutamic acids and related compounds.
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Convenient, asymmetric synthesis of enantiomerically pure 2',6'- dimethyltyrosine (DMT) via alkylation of chiral equivalent of nucleophilic glycine
TL;DR: Asymmetric synthesis of (S )-2′,6′-dimethyltyrosine (DMT) via reactions of 4′-benzyloxy-2.6.dimethyl bromide with Ni(II)-complexes of the chiral Schiff base of glycine with ( S )- o -[ N -( N -benzylonprolyl)amino]benzophenone was developed in this paper.
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Asymmetric Synthesis of α,β-Dialkyl-α-phenylalanines via Direct Alkylation of a Chiral Alanine Derivative with Racemic α-Alkylbenzyl Bromides. A Case of High Enantiomer Differentiation at Room Temperature
TL;DR: In this paper, the direct alkylation of a Ni(II)-complex of the chiral Schiff base of alanine with (S)-o-[N-(N-benzylprolyl)amino]benzophenone, with racemic α-alkyl benzyl bromides, is a synthetically feasible and methodologically advantageous approach to the target α,β-dialkylphenylalanines over previously reported methods.