V
Vera Hershkovitz
Researcher at Sheba Medical Center
Publications - 2
Citations - 1859
Vera Hershkovitz is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: MRNA modification & Mature messenger RNA. The author has an hindex of 2, co-authored 2 publications receiving 1366 citations.
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Journal ArticleDOI
m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
Shay Geula,Sharon Moshitch-Moshkovitz,Dan Dominissini,Abed AlFatah Mansour,Nitzan Kol,Mali Salmon-Divon,Vera Hershkovitz,Eyal Peer,Nofar Mor,Yair S. Manor,Moshe Shay Ben-Haim,Eran Eyal,Sharon Yunger,Yishay Pinto,Diego Jaitin,Sergey Viukov,Yoach Rais,Vladislav Krupalnik,Elad Chomsky,Mirie Zerbib,Itay Maza,Yoav Rechavi,Rada Massarwa,Suhair Hanna,Suhair Hanna,Ido Amit,Erez Y. Levanon,Ninette Amariglio,Ninette Amariglio,Noam Stern-Ginossar,Noa Novershtern,Gideon Rechavi,Jacob H. Hanna +32 more
TL;DR: It is shown that N6-methyladenosine (m6A), a messenger RNA (mRNA) modification present on transcripts of pluripotency factors, drives this transition from the pluripotent to the differentiated state.
Journal ArticleDOI
The dynamic N 1 -methyladenosine methylome in eukaryotic messenger RNA
Dan Dominissini,Dan Dominissini,Sigrid Nachtergaele,Sigrid Nachtergaele,Sharon Moshitch-Moshkovitz,Eyal Peer,Eyal Peer,Nitzan Kol,Moshe Shay Ben-Haim,Moshe Shay Ben-Haim,Qing Dai,Qing Dai,Ayelet Di Segni,Mali Salmon-Divon,Wesley C. Clark,Guanqun Zheng,Tao Pan,Oz Solomon,Oz Solomon,Eran Eyal,Vera Hershkovitz,Dali Han,Dali Han,Louis C. Dore,Louis C. Dore,Ninette Amariglio,Ninette Amariglio,Gideon Rechavi,Gideon Rechavi,Chuan He,Chuan He +30 more
TL;DR: It is shown that m1A is enriched around the start codon upstream of the first splice site: it preferentially decorates more structured regions around canonical and alternative translation initiation sites, is dynamic in response to physiological conditions, and correlates positively with protein production.