V
Verónica Lloréns-Rico
Researcher at Katholieke Universiteit Leuven
Publications - 20
Citations - 697
Verónica Lloréns-Rico is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Gene & Microbiome. The author has an hindex of 10, co-authored 18 publications receiving 505 citations. Previous affiliations of Verónica Lloréns-Rico include Pompeu Fabra University & European Bioinformatics Institute.
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Journal ArticleDOI
Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium
Maria Lluch-Senar,Maria Lluch-Senar,Javier Delgado,Javier Delgado,Wei-Hua Chen,Verónica Lloréns-Rico,Verónica Lloréns-Rico,Francis J. O’Reilly,Judith A. H. Wodke,Judith A. H. Wodke,Judith A. H. Wodke,E. Besray Unal,E. Besray Unal,Eva Yus,Eva Yus,Sira Martínez,Sira Martínez,Robert J. Nichols,Tony Ferrar,Tony Ferrar,Ana Vivancos,Arne Schmeisky,Jörg Stülke,Vera van Noort,Anne-Claude Gavin,Peer Bork,Luis Serrano,Luis Serrano,Luis Serrano +28 more
TL;DR: In the genome‐reduced bacterium Mycoplasma pneumoniae, it is found that small ORFs (smORFs; < 100 residues), accounting for 10% of all ORFs, are the most frequently essential genomic components, followed by conventional OrFs (49%).
Journal ArticleDOI
Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution
Maria Lluch-Senar,Maria Lluch-Senar,Khai Luong,Verónica Lloréns-Rico,Verónica Lloréns-Rico,Javier Delgado,Javier Delgado,Gang Fang,Kristi E. Spittle,Tyson A. Clark,Eric E. Schadt,Stephen Turner,Jonas Korlach,Luis Serrano,Luis Serrano,Luis Serrano +15 more
TL;DR: Analysis of the distribution of methylation sites across the genome of M. pneumoniae suggests a potential role for methylation in regulating the cell cycle, as well as in regulation of gene expression, in one of the first direct methylome profiling studies with single-base resolution from a bacterial organism.
Journal ArticleDOI
Bacterial antisense RNAs are mainly the product of transcriptional noise.
Verónica Lloréns-Rico,Verónica Lloréns-Rico,Jaime González Cano,Jaime González Cano,Tjerko Kamminga,Rosario Gil,Amparo Latorre,Wei-Hua Chen,Peer Bork,John I. Glass,Luis Serrano,Luis Serrano,Luis Serrano,Maria Lluch-Senar,Maria Lluch-Senar +14 more
TL;DR: It is shown, by comparative transcriptomics of 20 bacterial species and one chloroplast, that the number of asRNAs is exponentially dependent on the genomic AT content and that expression of asRNA at low levels exerts little impact in terms of energy consumption.
Journal ArticleDOI
Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community.
Kevin D'hoe,Stefan Vet,Stefan Vet,Karoline Faust,Frédéric Moens,Gwen Falony,Didier Gonze,Verónica Lloréns-Rico,Lendert Gelens,Jan Danckaert,Luc De Vuyst,Jeroen Raes,Jeroen Raes +12 more
TL;DR: This work established a synthetic community composed of three representative human gut isolates and explored their interactions under well-controlled conditions in vitro, demonstrating that strains grown in co-culture behaved differently than those in mono-culture and confirming their altered behavior at the transcriptional level.
Journal ArticleDOI
Comparative "-omics" in mycoplasma pneumoniae clinical isolates reveals key virulence factors
Maria Lluch-Senar,Luca Cozzuto,Jaime González Cano,Javier Delgado,Verónica Lloréns-Rico,Sabine Pereyre,Cécile Bébéar,Luis Serrano +7 more
TL;DR: This study has revealed that type 2 strains show higher expression levels of CARDS toxin, a protein recently shown to be one of the major factors of inflammation, and proposed thattype 2 strains could be more toxigenic than type 1 strains of M. pneumoniae.