W
Wes Warren
Researcher at Washington University in St. Louis
Publications - 6
Citations - 748
Wes Warren is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Structural variation. The author has an hindex of 6, co-authored 6 publications receiving 667 citations.
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Journal ArticleDOI
Discovery and genotyping of structural variation from long-read haploid genome sequence data
John Huddleston,Mark Chaisson,Karyn Meltz Steinberg,Wes Warren,Kendra Hoekzema,David Gordon,Tina A. Graves-Lindsay,Katherine M. Munson,Zev N. Kronenberg,Laura Vives,Paul Peluso,Matthew Boitano,Chen-Shin Chin,Jonas Korlach,Richard K. Wilson,Evan E. Eichler +15 more
TL;DR: Interestingly, when the authors repeat SV detection on a pseudodiploid genome constructed in silico by merging the two haploids, it is found that ∼59% of the heterozygous SVs are no longer detected by SMRT-SV, indicating that haploid resolution of long-read sequencing data will significantly increase sensitivity of SV detection.
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Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
Frédéric Veyrunes,Paul D. Waters,Pat Miethke,Willem Rens,Daniel McMillan,Amber E. Alsop,Frank Grützner,Janine E. Deakin,Camilla M. Whittington,Kyriena Schatzkamer,Colin Kremitzki,Tina Graves,Malcolm A. Ferguson-Smith,Wes Warren,Jennifer A. Marshall Graves +14 more
TL;DR: In other amniotes (reptiles and birds), sex is determined by a variety of different mechanisms that belong in two broad classes: genetic or environmental, although recent data show that some species combine both (Quinn et al. 2007) as mentioned in this paper.
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Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome
Martin Krzywinski,John W. Wallis,Claudia Gosele,Claudia Gosele,Ian Bosdet,Readman Chiu,Tina Graves,Oliver Hummel,Dan Layman,Carrie Mathewson,Natasja Wye,Baoli Zhu,Derek Albracht,Jennifer Asano,Sarah Barber,Mabel Brown-John,Susanna Chan,Steve Chand,Alison Cloutier,Jonathon Davito,Chris Fjell,Tony Gaige,Detlev Ganten,Noreen Girn,Kurtis Guggenheimer,Heinz Himmelbauer,Thomas Kreitler,Thomas Kreitler,Stephen Leach,Darlene Lee,Hans Lehrach,Michael Mayo,Kelly Mead,Teika Olson,Pawan Pandoh,Anna Liisa Prabhu,Heesun Shin,Simone Tänzer,Jason Thompson,Miranda Tsai,Jason Walker,George S. Yang,Mandeep Sekhon,LaDeana W. Hillier,Heike Zimdahl,Heike Zimdahl,Andre Marziali,Kazutoyo Osoegawa,Shaying Zhao,Asim Sarosh Siddiqui,Pieter J. de Jong,Wes Warren,Elaine R. Mardis,John Douglas Mcpherson,Richard K. Wilson,Norbert Hubner,Steven J.M. Jones,Marco A. Marra,Jacqueline E. Schein +58 more
TL;DR: The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome.
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Identification of transcriptome SNPs between Xiphophorus lines and species for assessing allele specific gene expression within F1 interspecies hybrids
Yingjia Shen,Julian M. Catchen,Tzintzuni Garcia,Angel Amores,Ion Beldorth,Jonathan R. Wagner,Ziping Zhang,John H. Postlethwait,Wes Warren,Manfred Schartl,Ronald B. Walter +10 more
TL;DR: The results show that Xiphophorus is a tractable vertebrate experimental model to investigate how genetic variations that occur during speciation may affect gene interactions and the regulation of gene expression.
Journal ArticleDOI
Alternative strategies for development of a reference transcriptome for quantification of allele specific expression in organisms having sparse genomic resources.
Yingjia Shen,Tzintzuni Garcia,Vagmita Pabuwal,Mikki Boswell,Amanda Pasquali,Ion Beldorth,Wes Warren,Manfred Schartl,William A. Cresko,Ronald B. Walter +9 more
TL;DR: Two strategies for analyzing allele specific expression within interspecies hybrids produced from crossing two Xiphophorus fish species are compared and it is indicated that indels between the two parental alleles are the major cause of the differences in results observed when employing these two methods.