A
Amber E. Alsop
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 32
Citations - 2764
Amber E. Alsop is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Genome & Bcl-2 Homologous Antagonist-Killer Protein. The author has an hindex of 20, co-authored 32 publications receiving 2563 citations. Previous affiliations of Amber E. Alsop include Australian Research Council & University of Cambridge.
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Journal ArticleDOI
Genome analysis of the platypus reveals unique signatures of evolution
Wesley C. Warren,LaDeana W. Hillier,Jennifer A. Marshall Graves,Ewan Birney,Chris P. Ponting,Frank Grützner,Katherine Belov,Webb Miller,Laura Clarke,Asif T. Chinwalla,Shiaw Pyng Yang,Andreas Heger,Devin P. Locke,Pat Miethke,Paul D. Waters,Frédéric Veyrunes,Frédéric Veyrunes,Lucinda Fulton,Bob Fulton,Tina Graves,John W. Wallis,Xose S. Puente,Carlos López-Otín,Gonzalo R. Ordóñez,Evan E. Eichler,Lin Chen,Ze Cheng,Janine E. Deakin,Amber E. Alsop,Katherine Thompson,Patrick J. Kirby,Anthony T. Papenfuss,Matthew Wakefield,Tsviya Olender,Doron Lancet,Gavin A. Huttley,Arian F.A. Smit,Andrew J Pask,Peter Temple-Smith,Peter Temple-Smith,Mark A. Batzer,Jerilyn A. Walker,Miriam K. Konkel,Robert S. Harris,Camilla M. Whittington,Emily S. W. Wong,Neil J. Gemmell,Emmanuel Buschiazzo,Iris M. Vargas Jentzsch,Angelika Merkel,Juergen Schmitz,Anja Zemann,Gennady Churakov,Jan Ole Kriegs,Juergen Brosius,Elizabeth P. Murchison,Ravi Sachidanandam,Carly Smith,Gregory J. Hannon,Enkhjargal Tsend-Ayush,Daniel McMillan,Rosalind Attenborough,Willem Rens,Malcolm A. Ferguson-Smith,Christophe Lefevre,Christophe Lefevre,Julie A. Sharp,Kevin R. Nicholas,David A. Ray,Michael Kube,Richard Reinhardt,Thomas H. Pringle,James Taylor,Russell C. Jones,Brett Nixon,Jean Louis Dacheux,Hitoshi Niwa,Yoko Sekita,Xiaoqiu Huang,Alexander Stark,Pouya Kheradpour,Manolis Kellis,Paul Flicek,Yuan Chen,Caleb Webber,Ross C. Hardison,Joanne O. Nelson,Kym Hallsworth-Pepin,Kim D. Delehaunty,Chris Markovic,Patrick Minx,Yucheng Feng,Colin Kremitzki,Makedonka Mitreva,Jarret Glasscock,Todd Wylie,Patricia Wohldmann,Prathapan Thiru,Michael N. Nhan,Craig Pohl,Scott M. Smith,Shunfeng Hou,Marilyn B. Renfree,Elaine R. Mardis,Richard K. Wilson +104 more
TL;DR: It is found that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypUS biology.
Journal ArticleDOI
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
Frédéric Veyrunes,Paul D. Waters,Pat Miethke,Willem Rens,Daniel McMillan,Amber E. Alsop,Frank Grützner,Janine E. Deakin,Camilla M. Whittington,Kyriena Schatzkamer,Colin Kremitzki,Tina Graves,Malcolm A. Ferguson-Smith,Wes Warren,Jennifer A. Marshall Graves +14 more
TL;DR: In other amniotes (reptiles and birds), sex is determined by a variety of different mechanisms that belong in two broad classes: genetic or environmental, although recent data show that some species combine both (Quinn et al. 2007) as mentioned in this paper.
Journal ArticleDOI
Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer
Elizabeth P. Murchison,Ole Schulz-Trieglaff,Zemin Ning,Ludmil B. Alexandrov,Markus J. Bauer,Beiyuan Fu,Matthew M. Hims,Zhihao Ding,Sergii Ivakhno,Caitlin Stewart,Bee Ling Ng,Wendy S.W. Wong,Bronwen Aken,Simon D. M. White,Amber E. Alsop,Jennifer Becq,Graham R. Bignell,R. Keira Cheetham,William Cheng,Thomas R. Connor,Anthony J. Cox,Zhi-Ping Feng,Zhi-Ping Feng,Yong Gu,Russell J. Grocock,Simon R. Harris,Irina Khrebtukova,Zoya Kingsbury,Mark Kowarsky,Alexandre Kreiss,Shujun Luo,John Marshall,David J. McBride,Lisa Murray,Anne-Maree Pearse,Keiran Raine,Isabelle Rasolonjatovo,Richard Shaw,Philip Tedder,Carolyn Tregidgo,Albert J. Vilella,David C. Wedge,Gregory M. Woods,Niall Anthony Gormley,Sean Humphray,Gary P. Schroth,Geoffrey Paul Smith,Kevin Hall,Stephen M. J. Searle,Nigel P. Carter,Anthony T. Papenfuss,Anthony T. Papenfuss,P. Andrew Futreal,Peter J. Campbell,Fengtang Yang,David R. Bentley,Dirk J. Evers,Michael R. Stratton +57 more
TL;DR: Genomic analysis suggests that the cancer first arose from a female Tasmanian devil and that the clone has subsequently genetically diverged during its spread across Tasmania.
Journal ArticleDOI
Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.
Michael J. O'Hare,Jacquelyn Bond,Catherine F. Clarke,Yasuhiro Takeuchi,Amanda J. Atherton,Catherine Berry,John Moody,Andrew Silver,Derek Davies,Amber E. Alsop,A. Munro Neville,Parmjit S. Jat +11 more
TL;DR: E ectopic expression of either the catalytic subunit of human telomerase (hTERT) or a temperature-sensitive mutant of simian virus 40 large-tumor antigen alone was not sufficient for immortalization of freshly isolated normal adult human mammary fibroblasts and endothelial cells, but a combination of both genes resulted in the efficient generation of immortal cell lines.
Journal ArticleDOI
Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting
Shunsuke Suzuki,Ryuichi Ono,Takanori Narita,Andrew J Pask,Geoffrey Shaw,Changshan Wang,Takashi Kohda,Amber E. Alsop,Jennifer A. Marshall Graves,Yuji Kohara,Fumitoshi Ishino,Marilyn B. Renfree,Tomoko Kaneko-Ishino +12 more
TL;DR: It is provided the first demonstration that DMR-associated genomic imprinting in eutherians can originate from the repression of exogenous DNA sequences and/or retrotransposons by DNA methylation.