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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing
George A. Truskey,Hardean E. Achneck,Nenad Bursac,Hon Fai Chan,Cindy Cheng,Cristina E. Fernandez,Sungmin Hong,Youngmee Jung,Timothy R. Koves,William E. Kraus,Kam W. Leong,Lauran Madden,William M. Reichert,Xuanhe Zhao +13 more
TL;DR: A microphysiological three-dimensional engineered human skeletal muscle system connected to a circulatory system that consists of a tissue-engineered blood vessel as part of a high-pressure arterial system that reproduces key mechanical behaviors of skeletal muscle in vivo is developed.
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Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort.
Susanne Breitner,Alexandra Schneider,Robert B. Devlin,Cavin K. Ward-Caviness,David Diaz-Sanchez,Lucas M. Neas,Wayne E. Cascio,Annette Peters,Elizabeth R. Hauser,Svati H. Shah,William E. Kraus +10 more
TL;DR: Delayed associations between short-term exposures to ambient PM2.5 or ozone and changes in metabolite levels of the glycine-ornithine-arginine metabolic axis and incomplete fatty acid oxidation associated with mitochondrial dysfunction are found.
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Exercise training and implantable cardioverter-defibrillator shocks in patients with heart failure: results from HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing).
Jonathan P. Piccini,Anne S. Hellkamp,David J. Whellan,Stephen J. Ellis,Steven J. Keteyian,William E. Kraus,Adrian F. Hernandez,James P. Daubert,Ileana L. Piña,Christopher M. O'Connor +9 more
TL;DR: The authors found no evidence of increased ICD shocks in patients with HF and reduced left ventricular function who underwent exercise training, and exercise therapy should not be prohibited in ICD recipients with HF.
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Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association.
Bethany Barone Gibbs,Marie-France Hivert,Gerald J Jerome,William E. Kraus,Sara K Rosenkranz,Erica N. Schorr,Nicole L. Spartano,Felipe Lobelo +7 more
TL;DR: In this article, the authors highlight the mild-moderate-risk patient groups indicated for lifestyle-only treatment for elevated blood pressure or cholesterol and describe recommendations, average effects, and additional considerations when prescribing lifestyle treatment with physical activity.
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Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.
Abanish Singh,Michael A. Babyak,Daniel K Nolan,Beverly H. Brummett,Rong Jiang,Ilene C. Siegler,William E. Kraus,Svati H. Shah,Redford B. Williams,Elizabeth R. Hauser +9 more
TL;DR: Analysis of related phenotypes identified gene-by-stress interaction effects for waist circumference, body mass index (BMI), fasting glucose, type II diabetes status, and common carotid intimal–medial thickness (CCIMT), supporting a proposed model of gene- by- stress interaction that connects cardiovascular disease (CVD) risk factor endophenotypes such as central obesity and increased blood glucose or diabetes to CVD itself.