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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Abstract 3196: High Heritabilities of Serum Metabolites and Differential Metabolomic Profiles in Families Burdened with Early Onset Coronary Artery Disease
Svati H. Shah,Christopher B. Newgard,James R. Bain,Robert Stevens,Brett R. Wenner,Michael J. Muehlbauer,Elaine Dowdy,Carol Haynes,Geoffrey S. Ginsburg,Elizabeth R. Hauser,William E. Kraus +10 more
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Conference Scene: Is personalized medicine ready for prime time?
TL;DR: Presentations are summarized on various topics: the future of genomic medicine, opportunities in pharmacogenomics and genetic testing; challenges in the clinical implementation of personalized medicine; systems medicine and biomedical informatics; the policy and education strategies for adopting personalized medicine.
Journal ArticleDOI
Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study.
Daniel C. Parker,William E. Kraus,Heather E. Whitson,Virginia B. Kraus,Patrick Smith,Harvey J. Cohen,Carl F. Pieper,Richard A. Faldowski,Katherine S. Hall,Janet L. Huebner,Olga Ilkayeva,James R. Bain,L. Kristin Newby,Kim M. Huffman +13 more
TL;DR: In this paper , the kynurenine pathway (KP) comprises a family of tryptophan-derived metabolites that some studies have reported are associated with poorer cognitive performance and an increased risk of Alzheimer's disease and related dementias.
Journal Article
Abstract 12679: Circulating High-Density Lipoprotein Particle Profiles Are Independently Associated With Heart Failure With Preserved Ejection Fraction and Predict Adverse Clinical Outcomes
Wynn G. Hunter,Robert W. McGarrah,Jacob P. Kelly,Carol Haynes,Damian M. Craig,Eric J. Velazquez,William E. Kraus,Svati H. Shah +7 more
TL;DR: High-density lipoprotein particle concentration and size impact atherogenesis and inflammation, both of which are implicated in the pathobiology of heart failure with murine studies, are implicated.
Journal Article
Abstract 1876: Development and Multi-Center Validation of a Blood-based Gene Expression Test for Diagnosis of Obstructive CAD in Non-Diabetic Patients
William E. Kraus,Steven A. Rosenberg,Michael Elashoff,Philip Beineke,Susan E. Daniels,James A. Wingrove,Whittemore G. Tingley,Philip T. Sager,Robert S. Schwartz,Szilard Voros,Steven G. Ellis,Naeem Tahirkheli,Ron Waksman,John A. McPherson,Eric J. Topol +14 more