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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Correlation of Peripheral-Blood Gene Expression With the Extent of Coronary Artery Stenosis
James A. Wingrove,Susan E. Daniels,Amy J. Sehnert,Whittemore G. Tingley,Michael Elashoff,Steven Rosenberg,Lutz Buellesfeld,Eberhard Grube,L. Kristin Newby,Geoffrey S. Ginsburg,William E. Kraus +10 more
TL;DR: Gene expression in peripheral-blood cells reflects the presence and extent of CAD in patients undergoing angiography and an analysis of the 14 genes demonstrated that gene expression was proportional to maximal coronary artery stenosis.
Journal ArticleDOI
Red cell distribution width, C-reactive protein, the complete blood count, and mortality in patients with coronary disease and a normal comparison population
Jason M. Lappé,Benjamin D. Horne,Benjamin D. Horne,Svati H. Shah,Heidi T May,Joseph B. Muhlestein,Joseph B. Muhlestein,Donald L. Lappé,Abdallah G. Kfoury,John F. Carlquist,John F. Carlquist,Deborah Budge,Rami Alharethi,Tami L Bair,William E. Kraus,Jeffrey L. Anderson,Jeffrey L. Anderson +16 more
TL;DR: Red cell distribution width was associated with mortality in patients with CAD and may provide clinically useful prognostication and Although RDW was correlated with hsCRP, they were independent predictors of mortality.
Journal ArticleDOI
Effects of Exercise Training Intensity on Pancreatic β-Cell Function
Cris A. Slentz,Charles J. Tanner,Lori A. Bateman,Michael T. Durheim,Kim M. Huffman,Joseph A. Houmard,William E. Kraus +6 more
TL;DR: It is observed that both moderate- and vigorous-intensity exercise training improved β-cell function, albeit through distinct mechanisms, and it is not clear which of these mechanisms is preferable for maintenance of metabolic health.
Journal ArticleDOI
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status
Sanjana Sood,Iain J. Gallagher,Katie Lunnon,Katie Lunnon,Eric Rullman,Aoife Keohane,Hannah Crossland,Bethan E. Phillips,Tommy Cederholm,Thomas E. Jensen,Luc J. C. van Loon,Lars Lannfelt,William E. Kraus,Philip J. Atherton,Robert Howard,Thomas Gustafsson,Angela Hodges,James A. Timmons +17 more
TL;DR: A novel and statistically robust multi-tissue RNA signature of human healthy ageing that can act as a diagnostic of future health, using only a peripheral blood sample is identified.
Journal ArticleDOI
Relation Between Volume of Exercise and Clinical Outcomes in Patients With Heart Failure
Steven J. Keteyian,Eric S. Leifer,Nancy Houston-Miller,William E. Kraus,Clinton A. Brawner,Christopher M. O'Connor,David J. Whellan,David J. Whellan,Lawton S. Cooper,Jerome L. Fleg,Dalane W. Kitzman,Alain Cohen-Solal,James A. Blumenthal,David S. Rendall,Ileana L. Piña +14 more
TL;DR: The findings support the use of regular exercise in the management of patients with chronic systolic HF, as volume of exercise is associated with the risk for clinical events, with only moderate levels of exercise needed to observe a clinical benefit.