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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
The ACTN3 R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults
Chelsea L. Deschamps,Kimberly E. Connors,Matthias S. Klein,Virginia L. Johnsen,Jane Shearer,Hans J. Vogel,Joseph M. Devaney,Heather Gordish-Dressman,Gina M. Many,Whitney Barfield,Eric P. Hoffman,William E. Kraus,Dustin S. Hittel +12 more
TL;DR: Results identify significant cardiometabolic effects associated with possessing one or more functional copies of the ACTN3 gene and identify the expression of alpha-actinin 3 protein in pulmonary artery smooth muscle, which may explain the genotype-specific differences in cardiovascular adaptation to acute exercise.
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Plasma lactate as a marker of metabolic health: Implications of elevated lactate for impairment of aerobic metabolism in the metabolic syndrome.
Terry E. Jones,Walter J. Pories,Joseph A. Houmard,Charles J. Tanner,Donghai Zheng,Kai Zou,Paul M. Coen,Bret H. Goodpaster,William E. Kraus,G. Lynis Dohm +9 more
TL;DR: Fasting plasma lactate was elevated in obese subjects with the metabolic syndrome compared with healthy lean individuals, and was reduced by exercise and bariatric surgery, interventions that improve metabolic health and risk for subsequent disease.
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Diabetes status differentiates endothelial function and plasma nitrite response to exercise stress in peripheral arterial disease following supervised training
Jason D. Allen,Thomas Stabler,Aarti A. Kenjale,Katherine L. Ham,Jennifer L. Robbins,Brian D. Duscha,William E. Kraus,Brian H. Annex +7 more
TL;DR: T2D in the presence of PAD attenuated improvements in endothelial function, net plasma nitrite, and COT following SET, suggesting that T2D maybe associated with an inability to endogenously increase vascular NO bioavailability to SET.
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Genetically Guided Statin Therapy on Statin Perceptions, Adherence, and Cholesterol Lowering: A Pilot Implementation Study in Primary Care Patients
Josephine H. Li,Scott V. Joy,Susanne B. Haga,Lori A. Orlando,William E. Kraus,Geoffrey S. Ginsburg,Deepak Voora +6 more
TL;DR: This novel intervention may improve patients’ perceptions of statins and physician behaviors that promote higher statin adherence and lower LDL-c.
Journal Article
Genetic approaches for the investigation of genes associated with coronary heart disease : Genetics of coronary heart disease: Current understanding and future prospects
TL;DR: Wilson PWF, Myers RH, Larson MG, et al. as discussed by the authors found that the inherited component of coronary heart disease is likely several years away atbest, however, a new understandingwill be reached of the relation between inherited risksand outcomes in cardiovascular disease.