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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Adverse Cardiovascular Response to Aerobic Exercise Training: Is This a Concern?
Eric S. Leifer,Catherine R. Mikus,Laura Karavirta,Benjamin D. Resnick,William E. Kraus,Keijo Häkkinen,Conrad P. Earnest,Jerome L. Fleg +7 more
TL;DR: Findings do not support the concept that aerobic exercise training increases the risk of adverse changes in the CV biomarkers the authors studied and suggest that supervised endurance training improves physical fitness and various cardiovascular biomarkers.
Journal ArticleDOI
Effect of exercise training on ventricular function, dyssynchrony, resting myocardial perfusion, and clinical outcomes in patients with heart failure : A nuclear ancillary study of Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION); design and rationale
Daniel Bensimhon,George L. Adams,David J. Whellan,Robert Pagnanelli,Mark A. Trimble,Benjamin A. Lee,Kerry L. Lee,Stephen J. Ellis,William E. Kraus,David S. Rendall,Ami E. Iskandrian,Christopher M. O'Connor,Salvador Borges-Neto +12 more
TL;DR: This substudy aims to harness the power of a large heart failure trial to further delineate the utility of technetium Tc 99m gated SPECT imaging and first-pass radionuclide ventriculography for predicting important clinical outcomes in this population of patients with heart failure.
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Pilot study: incorporation of pharmacogenetic testing in medication therapy management services
Susanne B. Haga,Nancy M. Allen LaPointe,Jivan Moaddeb,Rachel Mills,Mahesh J. Patel,William E. Kraus +5 more
TL;DR: A pilot study evaluating the integration of pharmacogenetic testing into pharmacist-delivered medication therapy management (MTM) services for cardiology patients taking three or more medications including simvastatin or clopidogrel is described.
Journal ArticleDOI
Electrical pacing induces adenylyl cyclase in skeletal muscle independent of the beta-adrenergic receptor.
TL;DR: It is concluded that EP appears to increase cAMP through mechanisms independent of the beta-AR and through mechanisms that may involve alterations at the level of adenylyl cyclase.
Journal ArticleDOI
An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
Deepak Voora,Adrian Coles,Kerry L. Lee,Udo Hoffmann,James A. Wingrove,Brian Kent Rhees,Lin Huang,Susan E. Daniels,Mark Monane,Steven A. Rosenberg,Svati H. Shah,William E. Kraus,Geoffrey S. Ginsburg,Pamela S. Douglas +13 more
TL;DR: A blood‐based genomic test for detecting oCAD significantly predicts near‐term revascularization procedures, but not non‐revascularization events.