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William E. Kraus
Researcher at Duke University
Publications - 625
Citations - 40583
William E. Kraus is an academic researcher from Duke University. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 93, co-authored 565 publications receiving 33692 citations. Previous affiliations of William E. Kraus include University of Texas Southwestern Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure
Tariq Ahmad,Tariq Ahmad,Mona Fiuzat,Mona Fiuzat,Daniel B. Mark,Daniel B. Mark,Ben Neely,Megan L. Neely,William E. Kraus,Dalane W. Kitzman,David J. Whellan,Mark P. Donahue,Faiez Zannad,Ileana L. Piña,Kirkwood F. Adams,Christopher M. O'Connor,Christopher M. O'Connor,G. Michael Felker,G. Michael Felker +18 more
TL;DR: Exercise training did not lead to meaningful changes in biomarker levels of myocardial stress, inflammation, or necrosis in patients with chronic HF, even after adjustment for a comprehensive set of known predictors.
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E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins.
TL;DR: E1A mediates repression of muscle-specific gene transcription through its amino-terminal domain and it is proposed that this may involve a direct physical interaction between E1A and the bHLH region of myogenic determination proteins.
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Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)
Lauren B. Cooper,Robert J. Mentz,Jie Lena Sun,Phillip J. Schulte,Jerome L. Fleg,Lawton S. Cooper,Ileana L. Piña,Eric S. Leifer,William E. Kraus,David J. Whellan,Steven J. Keteyian,Christopher M. O'Connor +11 more
TL;DR: Poor social support and high barriers to exercise were associated with lower exercise time, and for cardiovascular death or HF hospitalization, exercise training had a greater impact on patients with lower BTES.
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Exercise-Induced Changes in Metabolic Intermediates, Hormones, and Inflammatory Markers Associated With Improvements in Insulin Sensitivity
Kim M. Huffman,Cris A. Slentz,Lori A. Bateman,Dana K. Thompson,Michael J. Muehlbauer,James R. Bain,Robert Stevens,Brett R. Wenner,Virginia B. Kraus,Christopher B. Newgard,William E. Kraus +10 more
TL;DR: These observations support prior observations in animal models that exercise training promotes more efficient mitochondrial β-oxidation and challenges current hypotheses regarding exercise training and glycine metabolism.
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The AMPK/p27Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells
James P. White,Andrew N. Billin,Milton Campbell,Alan J. Russell,Kim M. Huffman,William E. Kraus +5 more
TL;DR: In this paper, the AMPK/p27Kip1 pathway was found to regulate the balance between autophagy, apoptosis, and senescence in aged skeletal muscle stem cells.