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William Fenical
Researcher at University of California, San Diego
Publications - 591
Citations - 36313
William Fenical is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Streptomyces & Laurencia. The author has an hindex of 97, co-authored 578 publications receiving 34003 citations. Previous affiliations of William Fenical include University of North Carolina at Chapel Hill & University of Concepción.
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Journal ArticleDOI
Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells.
Jihye Lee,Chathurika D.B. Gamage,Geum Jin Kim,Prima F. Hillman,Chaeyoung Lee,Eunyoung Lee,Hyukjae Choi,Hangun Kim,Sang Jip Nam,William Fenical +9 more
TL;DR: A cyclic tetrapeptide, androsamide (1), was isolated from a marine actinomycete of the genus Nocardiopsis, strain CNT-189 and strongly suppressed the motility of Caco2 cells caused by epithelial-mesenchymal transition.
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Genetic Complementation of the Obligate Marine Actinobacterium Salinispora tropica with the Large Mechanosensitive Channel Gene mscL Rescues Cells from Osmotic Downshock
TL;DR: Enhanced survival of the S. tropica transformant provides experimental evidence that the loss of mscL is associated with the failure of Salinispora spp.
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PGF2α-9-O-Acetate Methyl Ester, A Minor Naturally Occurring Prostaglandin from the Gorgonian Coral Plexaura homomalla
Amiram Groweiss,William Fenical +1 more
TL;DR: PGF 2α -9-O-acetate methyl ester has been found as a natural product in extracts of the gorgonian coral Plexaura homomalla collected in the Bahama islands.
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Marinopyrones A–D, α-pyrones from marine-derived actinomycetes of the family Nocardiopsaceae
Jihye Lee,Chulkyeong Han,Tae Gu Lee,Jungwook Chin,Hyukjae Choi,Wonjae Lee,Man-Jeong Paik,Dong Hwan Won,Gyusang Jeong,Jaeyoung Ko,Yeo Joon Yoon,Sang-Jip Nam,William Fenical,Heonjoong Kang +13 more
TL;DR: Marinopyrones A–C are only the second reported natural products from the rare halophilic genus Streptomonospora, and the structures of which were elucidated by interpretation of 1D and 2D NMR and HRMS spectroscopic data.
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Actinoquinolines A and B, anti-inflammatory quinoline alkaloids from a marine-derived Streptomyces sp., strain CNP975.
TL;DR: An examination of the culture broth of a Streptomyces sp.