W
William Fenical
Researcher at University of California, San Diego
Publications - 591
Citations - 36313
William Fenical is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Streptomyces & Laurencia. The author has an hindex of 97, co-authored 578 publications receiving 34003 citations. Previous affiliations of William Fenical include University of North Carolina at Chapel Hill & University of Concepción.
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Journal ArticleDOI
Verrucosamide, a Cytotoxic 1,4-Thiazepane-Containing Thiodepsipeptide from a Marine-Derived Actinomycete
Vimal Nair,Min-Cheol Kim,James A. Golen,Arnold L. Rheingold,Gabriel A Castro,Paul R. Jensen,William Fenical +6 more
TL;DR: A new cytotoxic thiodepsipeptide, verrucosamide (1), was isolated along with the known, related cyclic peptide thiocoraline, from the extract of a marine-derived actinomycete, a Verrucosispora sp.
Journal ArticleDOI
Saliniquinones A—F, New Members of the Highly Cytotoxic Anthraquinone-γ-pyrones from the Marine Actinomycete Salinispora arenicola.
Brian T. Murphy,Tadigoppula Narender,Christopher A. Kauffman,Matthew Woolery,Paul R. Jensen,William Fenical +5 more
TL;DR: In this paper, Saliniquinone A (1) exhibited potent inhibition of the human colon adenocarcinoma cell line (HCT-116) with an IC50 of 9.9 × 10-9 M.
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Marinoterpins A-C: Rare Linear Merosesterterpenoids from Marine-Derived Actinomycete Bacteria of the Family Streptomycetaceae.
Min-Cheol Kim,Jaclyn M. Winter,Ratnakar N. Asolkar,Chollaratt Boonlarppradab,Reiko Cullum,William Fenical +5 more
TL;DR: The chemical examination of two undescribed marine actinobacteria has yielded three rare merosesterterpenoids, marinoterpins A-C (1-3, respectively), which represent new chemical motifs, combining quinoline-N-oxides with a linear sesterterpenoid side chain.
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Structure assignments of two new C-18-oxygenated steroidal ketals isolated from a pacific soft coral of the genus Sinularia
TL;DR: Two new C-18-oxygenated sterols possessing a spiroketal function have been isolated from a soft coral of the genus Sinularia and the proposed structures are based on spectral data.