W
William G. Nelson
Researcher at Johns Hopkins University School of Medicine
Publications - 302
Citations - 32149
William G. Nelson is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Prostate cancer & Prostate. The author has an hindex of 93, co-authored 292 publications receiving 30356 citations. Previous affiliations of William G. Nelson include New York University & Johns Hopkins University.
Papers
More filters
Journal ArticleDOI
Serum vascular endothelial growth factor is a candidate biomarker of metastatic tumor response to ex vivo gene therapy of renal cell cancer
Angelo A. Baccala Md,Hua Zhong,Shirley M. Clift,William G. Nelson,Fray F. Marshall,Theodore J. Passe,Neil B. Gambill,Jonathan W. Simons +7 more
TL;DR: Close correlation between changes in serum immunoreactive vascular endothelial growth factor 165 levels and metastatic tumor burden measured by computed tomography scan before treatment, during the antitumor response, and during early progression in a patient treated with ex vivo gene therapy for renal cell carcinoma is reported.
Journal Article
8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells.
Antony R. Parker,Robert N. O'Meally,Dwight H Oliver,Li Hua,William G. Nelson,Theodore L. DeWeese,James R. Eshleman +6 more
TL;DR: This work hypothesized that 8-hydroxyguanosine could be involved in the carcinogenesis of CRC and found elevations in 5 of 15 MSS CRC cell lines analyzed, which may reflect a MSS mutator phenotype contributing to the development of CRC.
Journal ArticleDOI
Racial/ethnic differences in serum sex steroid hormone concentrations in US adolescent males
David S. Lopez,David S. Lopez,Sarah B. Peskoe,Corinne E. Joshu,Adrian S. Dobs,Manning Feinleib,Norma Kanarek,William G. Nelson,Elizabeth Selvin,Sabine Rohrmann,Elizabeth A. Platz +10 more
TL;DR: In adolescent males, non-Hispanic blacks did not have a higher testosterone concentration thanNon-Hispanic whites, and Mexican–Americans had the highest testosterone concentration, patterns similar to adult males.
Journal ArticleDOI
Time-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2
TL;DR: The results provide proof of principle for using TR-FRET–based HTS to identify small-molecule inhibitors of MBD2 and other DNA-protein interactions and are compared to FP and time-resolved fluorescence resonance energy transfer.
Journal ArticleDOI
Association between sex steroid hormones and hematocrit in a nationally representative sample of men.
Channing J. Paller,Meredith S. Shiels,Sabine Rohrmann,Andy Menke,Nader Rifai,William G. Nelson,Elizabeth A. Platz,Adrian S. Dobs +7 more
TL;DR: Changes in sex hormone levels with aging may contribute to the increased prevalence of anemia and thromboembolic stroke in men as they age, and high total and free estradiol levels were associated with high hematocrit.