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Elizabeth A. Platz

Researcher at Johns Hopkins University

Publications -  441
Citations -  18098

Elizabeth A. Platz is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 75, co-authored 389 publications receiving 16119 citations. Previous affiliations of Elizabeth A. Platz include Johns Hopkins University School of Medicine.

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Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R. Huyghe, +224 more
- 01 Jan 2019 - 
TL;DR: Genome-wide association analyses based on whole-genome sequencing and imputation identify 40 new risk variants for colorectal cancer, including a strongly protective low-frequency variant at CHD1 and loci implicating signaling and immune function in disease etiology.
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Hypermethylation of the Human Glutathione S-Transferase-π Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate : A Detailed Study Using Laser-Capture Microdissection

TL;DR: The hypothesis that atrophic epithelium in a subset of PIA lesions may lead to high-grade PIN and/or adenocarcinoma is supported, because these atrophic lesions are so prevalent and extensive, even though only a small subset contains this somatic DNA alteration.
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Association between markers of the metabolic syndrome and lower urinary tract symptoms in the Third National Health and Nutrition Examination Survey (NHANES III)

TL;DR: Findings support the role for metabolic perturbations in the etiology of LUTS, which often result from prostate enlargement and heightened tone of prostate and bladder smooth muscle.