W
William J. Murphy
Researcher at Texas A&M University
Publications - 320
Citations - 27304
William J. Murphy is an academic researcher from Texas A&M University. The author has contributed to research in topics: Genome & Immune system. The author has an hindex of 80, co-authored 293 publications receiving 25360 citations. Previous affiliations of William J. Murphy include Pontifícia Universidade Católica do Rio Grande do Sul & Texas College.
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Journal ArticleDOI
A gene catalogue of the euchromatic male-specific region of the horse Y chromosome: comparison with human and other mammals.
Nandina Paria,Terje Raudsepp,Alison J. Pearks Wilkerson,Patricia C. M. O’Brien,M.A. Ferguson-Smith,Charles C. Love,Carolyn E. Arnold,Peter C. Rakestraw,William J. Murphy,B.P. Chowdhary +9 more
TL;DR: It is demonstrated that the horse MSY harbors 20 X-degenerate genes with known orthologs in other eutherian species, and the functions of MSY genes are predominantly related to testis and spermatogenesis.
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Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine.
TL;DR: GH exerts significant direct hematopoietic growth-promoting effects in vivo and may be of potential clinical use to promote hematocrit values and white blood cell counts in the face of myelotoxic therapy.
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Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax.
Jamie L. Szocinski,Annette R. Khaled,Julie A. Hixon,Douglas Halverson,Satoshi Funakoshi,William C. Fanslow,Ann Boyd,Dennis D. Taub,Scott K. Durum,Clay B. Siegall,Dan L. Longo,William J. Murphy +11 more
TL;DR: It is demonstrated that CD40 ligation of aggressive histology B-lymphoma cells results in inhibition both in vitro and in vivo and thus may be of potential clinical use in their treatment.
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Radiation hybrid mapping of 304 novel microsatellites in the domestic cat genome.
Marilyn Menotti-Raymond,Victor A. David,Richa Agarwala,Alejandro A. Schäffer,Robert M. Stephens,Stephen J. O'Brien,William J. Murphy +6 more
TL;DR: These 304 novel polymorphic repeat loci in the feline genome provide a useful tool for undertaking full-genome scans to identify genes associated with phenotypes of interest, such as those relating to hereditary disease, coat color, patterning and morphology.
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Phylogenetic assessment of introns and SINEs within the Y chromosome using the cat family felidae as a species tree.
TL;DR: The data suggest X-degenerate genes within the NRY are singularly powerful markers and offer a valuable patrilineal perspective in species evolution.