William J. Murphy

TL;DR: Genomic distances between species, dominated by inversions (reversals) and translocations, are presented in a first multispecies attempt using ordered mapping data to reconstruct the evolutionary exchanges that preceded modern placental mammal genomes.

TL;DR: stimulation of CD40 by its ligand may be beneficial in accelerating both immune and hematopoietic recovery in the setting of bone marrow transplantation.

TL;DR: The young timetree estimates for eulipotyphlan families and the polytomy are due to an inverted ingroup-outgroup arrangement of the tree, the result of using Tracer rather than TreeAnnotator to compile interfamilial divergence times, and of not enforcing the monophly of well-established clades such as Laurasiatheria and EulipOTyphla.

TL;DR: Results indicate that decreased toxicity and increased efficacy of bortezomib in murine allo-BMT can be achieved by removal of CD4(+) T cells from the graft or by inhibiting TNFalpha.

TL;DR: The results together with published data on the Sciuridae allow the formulation of a putative rodent ancestral karyotypes that is thought to comprise the following 26 human chromosomal segments and/or segmental associations, providing insights into the likely composition of the ancestral rodent karyotype and an improved understanding of placental genome evolution.