W
William J. Murphy
Researcher at Texas A&M University
Publications - 320
Citations - 27304
William J. Murphy is an academic researcher from Texas A&M University. The author has contributed to research in topics: Genome & Immune system. The author has an hindex of 80, co-authored 293 publications receiving 25360 citations. Previous affiliations of William J. Murphy include Pontifícia Universidade Católica do Rio Grande do Sul & Texas College.
Papers
More filters
Journal ArticleDOI
New strategies for preventing graft-versus-host disease.
TL;DR: Questions about the variables that affect its induction and severity; the effector mechanisms; and whether GVHD can be suppressed yet GVT effects be maintained need answers to enable us to design successful approaches for intervention.
Journal Article
In Vivo Antitumor Effects of Unconjugated CD30 Monoclonal Antibodies on Human Anaplastic Large-Cell Lymphoma Xenografts
Zhigang Tian,Dan L. Longo,Satoshi Funakoshi,Osamu Asai,Douglas K. Ferris,Michael B Widmer,William J. Murphy +6 more
TL;DR: Anti- CD30 treatment is efficacious for CD30+ ALCL cell lines in vivo, and unconjugated anti-CD30 moAbs may be of potential clinical use.
Journal ArticleDOI
Role for CD40-CD40 ligand interactions in the immune response to solid tumours.
Anton B. Alexandroff,Andrew Jackson,T. Paterson,Joanne L. Haley,James A. Ross,Dan L. Longo,William J. Murphy,Keith James,Dennis D. Taub +8 more
TL;DR: The presence of CD40 on the surface of carcinoma lines was found to be an important factor in the generation of tumour-specific T cell responses.
Journal ArticleDOI
The Birth and Death of Olfactory Receptor Gene Families in Mammalian Niche Adaptation.
Graham M. Hughes,Emma S. M. Boston,John A. Finarelli,William J. Murphy,Desmond G. Higgins,Emma C. Teeling +5 more
TL;DR: This study demonstrates the utility of species‐specific duplications in elucidating gene family evolution, revealing how the OR repertoire has undergone expansion and contraction with respect to a number of ecological adaptations in mammals.
Journal ArticleDOI
Phylogeny of the Neotropical killifish family Rivulidae (Cyprinodontiformes, Aplocheiloidei) inferred from mitochondrial DNA sequences.
TL;DR: The suite of adaptations necessary for an annual life history has clearly been lost several times in the course of rivulid evolution and there is a considerable increase in substitution rate in most annual lineages relative to the nonannual Rivulus species.