W
Won Ho Kim
Researcher at Yonsei University
Publications - 748
Citations - 21405
Won Ho Kim is an academic researcher from Yonsei University. The author has contributed to research in topics: Inflammatory bowel disease & Colorectal cancer. The author has an hindex of 61, co-authored 704 publications receiving 18779 citations. Previous affiliations of Won Ho Kim include KAIST & Seoul National University.
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Journal ArticleDOI
Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes
Svetlana Radaeva,Barbara Jaruga,Feng Hong,Won Ho Kim,Saijun Fan,Hongbo Cai,Stephen C. Strom,Youhua Liu,Osama El–Assal,Bin Gao +9 more
TL;DR: IFN-α directly targets human hepatocytes, followed by activation of multiple STATs and regulation of a wide variety of genes, which may contribute to the antiviral and antitumor activities of IFN- α in human liver.
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Development and Validation of Novel Diagnostic Criteria for Intestinal Behçet's Disease in Korean Patients With Ileocolonic Ulcers
Jae Hee Cheon,Eun Soo Kim,Sung Jae Shin,Tae Il Kim,Kang Moon Lee,Sang Woo Kim,Joo Sung Kim,You Sun Kim,Chang Hwan Choi,Byong Duk Ye,Suk-Kyun Yang,Eunhee Choi,Won Ho Kim +12 more
TL;DR: These newly proposed, simple criteria might be useful in diagnosing intestinal BD, especially in patients with ileocolonic ulcers who do not fully satisfy the diagnostic criteria of systemic BD.
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Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease
TL;DR: Insight is provided into the genetic and epigenetic interactions in the IL-23R/IL-17 axis that are associated with elevated expression of IL-17 and IBD pathogenesis and a significant inverse correlation between methylation extent of IVS1+17 and IL- 17A mRNA level.
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Long-term outcome of palliative therapy for malignant colorectal obstruction in patients with unresectable metastatic colorectal cancers: endoscopic stenting versus surgery.
TL;DR: SEMSs were not only an effective and acceptable therapy for initial palliation of malignant colorectal obstruction, but they also showed long-term efficacy comparable to that with surgery.
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NFATc4 and ATF3 Negatively Regulate Adiponectin Gene Expression in 3T3-L1 Adipocytes
Hyun Bae Kim,Minyoung Kong,Tae Min Kim,Young Ho Suh,Won Ho Kim,Joo Hyun Lim,Ji Hyun Song,Myeong Ho Jung +7 more
TL;DR: This study demonstrates for the first time that NFATc4 and ATF3 function as negative regulators of adiponectin gene expression, which may play critical roles in downregulating adip onectin expression in obesity and type 2 diabetes.