Qichao Yu

TL;DR: A comprehensive picture of the HCC ecosystem provides deeper insights into immune evasion mechanisms associated with tumor relapse, including those that dampen DC antigen presentation and recruit innate-like CD8+ T cells.

TL;DR: 2-Substituted 4,4-dimethyloxazolines (DMOX) have been found to be a useful alternative to the commonly used methyl esters for the localization of unsaturated bounds and other substituents in the fatty chain by mass spectrometry.

TL;DR: A new approach to the derivatization and analysis of long chain polyunsaturated fatty acids is described, based on the formation of 2-alkenyl-4,4-dimethyloxazolines by condensation of the starting material with 2-amino-2-methylpropanol.

TL;DR: A new high throughput platform to prepare single-cell RNA on a nanoliter scale based on a customized microwell chip provides a transcriptome characterization of HeLa S3 cells at the single cell level, and is a demonstration of the power of single cell RNA-seq analysis of virally infected cells and cancers.

TL;DR: In this paper, the authors reveal that the transcriptional dynamics of CTCs were associated with stress response, cell cycle and immune-evasion signaling during hematogeneous transportation, and identify chemokine CCL5 as an important mediator for CTC immune evasion.