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Xiangling Yang
Researcher at Sun Yat-sen University
Publications - 70
Citations - 2520
Xiangling Yang is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 24, co-authored 57 publications receiving 1908 citations. Previous affiliations of Xiangling Yang include University of Toronto & Sunnybrook Health Sciences Centre.
Papers
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Journal ArticleDOI
m 6 A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1
Yingmin Wu,Xiangling Yang,Zhuojia Chen,Lin Tian,Guanmin Jiang,Feng Chen,Jiexin Li,Panpan An,Linlin Lu,Nan Luo,Jun Du,Hong Shan,Huanliang Liu,Hong-Sheng Wang +13 more
TL;DR: m6A-induced lncRNA RP11 can trigger the dissemination of CRC cells via post-translational upregulation of Zeb1, and clinical analysis showed that m6A can regulate the expression of RP11.
Journal ArticleDOI
Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion
Xiangling Yang,William W. Du,Haoran Li,Fengqiong Liu,Anna Khorshidi,Zina Jeyapalan Rutnam,Burton B. Yang +6 more
TL;DR: The results demonstrated that mature miRNA can function coordinately with its passenger strand, enhancing the repressive ability of a miRNA by binding the same target.
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Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways
Sze Wan Shan,Sze Wan Shan,Ling Fang,Ling Fang,Tatiana Shatseva,Tatiana Shatseva,Zina Jeyapalan Rutnam,Zina Jeyapalan Rutnam,Xiangling Yang,Xiangling Yang,William W. Du,William W. Du,Wei-Yang Lu,Jim W. Xuan,Zhaoqun Deng,Zhaoqun Deng,Burton B. Yang,Burton B. Yang +17 more
TL;DR: It is demonstrated that a mature miRNA can function synergistically with its passenger strand leading to the same phenotype but by regulating different targets located in different signaling pathways.
Journal ArticleDOI
MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11
Siragam,Zina Jeyapalan Rutnam,Yang W,Fang L,Linlin Luo,Xiangling Yang,Li M,Deng Z,Qian J,Chun Peng,Yang Bb +10 more
TL;DR: A regulatory role of miR-98 is defined in tumor angiogenesis and invasion through repressed ALK4 and MMP11 expression through repression of 3'-untranslated regions of ALK 4 and M MP11.
Journal ArticleDOI
MicroRNA miR-24 enhances tumor invasion and metastasis by targeting PTPN9 and PTPRF to promote EGF signaling
William W. Du,Ling Fang,Ling Fang,Minhui Li,Minhui Li,Minhui Li,Xiangling Yang,Xiangling Yang,Yaoyun Liang,Chun Peng,Chun Peng,Wei Qian,Yunxia O'Malley,Ryan W. Askeland,Sonia L. Sugg,Jun Qian,Jiang Lin,Zide Jiang,Albert Yee,Michael Sefton,Zhaoqun Deng,Zhaoqun Deng,Sze Wan Shan,Sze Wan Shan,Chia Hui Wang,Chia Hui Wang,Burton B. Yang,Burton B. Yang +27 more
TL;DR: The results suggest that miR-24 plays a key role in breast cancer invasion and metastasis and could potentially be a target for cancer intervention.