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Xiaoying Zhang
Researcher at Sichuan University
Publications - 17
Citations - 267
Xiaoying Zhang is an academic researcher from Sichuan University. The author has contributed to research in topics: Acute pancreatitis & Medicine. The author has an hindex of 6, co-authored 11 publications receiving 145 citations. Previous affiliations of Xiaoying Zhang include Royal Liverpool University Hospital & University of Liverpool.
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Journal ArticleDOI
Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release.
Wei Huang,Wei Huang,Wei Huang,Matthew C Cane,Rajarshi Mukherjee,Rajarshi Mukherjee,Peter Szatmary,Peter Szatmary,Xiaoying Zhang,Xiaoying Zhang,Victoria Elliott,Yulin Ouyang,Yulin Ouyang,Michael Chvanov,Michael Chvanov,Diane Latawiec,Li Wen,Li Wen,David Booth,Andrea C. Haynes,Ole H. Petersen,Alexei V. Tepikin,David N. Criddle,David N. Criddle,Robert Sutton +24 more
TL;DR: Caffeine and its dimethylxanthine metabolites reduced pathological IP3R-mediated pancreatic acinar Ca2+ signals but only caffeine ameliorated experimental AP.
Journal ArticleDOI
Exocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis
Wei Huang,Daniel De la Iglesia-García,Iria Bastón-Rey,Cristina Calviño-Suarez,Jose Lariño-Noia,Julio Iglesias-Garcia,Na Shi,Xiaoying Zhang,Xiaoying Zhang,Wenhao Cai,Lihui Deng,Danielle Moore,Vikesh K. Singh,Qing Xia,John A. Windsor,J. Enrique Domínguez-Muñoz,Robert Sutton +16 more
TL;DR: The prevalence of EPI during admission and follow-up is substantial in patients with a first attack of AP, and unanswered questions remain about the way this is managed, and further RCTs are indicated.
Journal ArticleDOI
Protective effects of flavonoids from Coreopsis tinctoria Nutt. on experimental acute pancreatitis via Nrf-2/ARE-mediated antioxidant pathways.
Dan Du,Linbo Yao,Rui Zhang,Na Shi,Yan Shen,Xinmin Yang,Xiaoying Zhang,Tao Jin,Tingting Liu,Liqiang Hu,Zhihua Xing,David N. Criddle,Qing Xia,Wei Huang,Wei Huang,Robert Sutton +15 more
TL;DR: Flavonoid C1 from C. tinctoria was protective in experimental AP and this effect may at least in part be attributed to its antioxidant effects by activation of Nrf2-mediated pathways, which suggest the potential utilisation of C. Tinctoria to treat AP.
Journal ArticleDOI
The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis
Quentin M. Nunes,Dunhao Su,Philip Brownridge,Deborah M. Simpson,Changye Sun,Changye Sun,Yong Li,Yong Li,Thao P. Bui,Xiaoying Zhang,Wei Huang,Wei Huang,Daniel J. Rigden,Robert J. Beynon,Robert Sutton,David G. Fernig +15 more
TL;DR: The identification of heparin affinity proteomics was used to identify extracellular HBPs in pancreas and plasma of normal mice and in a caerulein mouse model of AP to determine which HBPs may have potential applications in the management of AP.
Journal ArticleDOI
Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine.
Xiaoying Zhang,Tao Jin,Tao Jin,Na Shi,Linbo Yao,Xinmin Yang,Chenxia Han,Li Wen,Dan Du,Peter Szatmary,Rajarshi Mukherjee,Tingting Liu,Qing Xia,David N. Criddle,Wei Huang,Michael Chvanov,Robert Sutton +16 more
TL;DR: Significant differences in the mechanisms of pancreatic injury induced by different basic amino acids are demonstrated and the lack of effect of treatments on L-arginine-induced AP may be due to conversion to L-ornithine in the urea cycle.