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Xudong Xu
Researcher at Peking Union Medical College
Publications - 169
Citations - 2180
Xudong Xu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 20, co-authored 136 publications receiving 1609 citations. Previous affiliations of Xudong Xu include Chinese Ministry of Education.
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Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography-mass spectrometry.
TL;DR: This paper mainly focuses on screening and characterization of phenols (including flavonoids), alkaloids, terpenoids, steroids, coumarins, lignans, and miscellaneous compounds in respective herbs and biological samples, as well as traditional Chinese medicine prescriptions using tandem mass spectrometer.
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Anti-Hyperlipidemic Effects and Potential Mechanisms of Action of the Caffeoylquinic Acid-Rich Pandanus tectorius Fruit Extract in Hamsters Fed a High Fat-Diet
Xiaopo Zhang,Chongming Wu,Haifeng Wu,Ling-hui Sheng,Yan Su,Yan Su,Xue Zhang,Xue Zhang,Hong Luan,Hong Luan,Guibo Sun,Xiaobo Sun,Yu Tian,Yubin Ji,Peng Guo,Xudong Xu +15 more
TL;DR: It is suggested that administration of the PTF-b enriched in CQAs moderates hyperlipidemia and improves the liver lipid profile.
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Daphniphyllum Alkaloids: Recent Findings on Chemistry and Pharmacology
TL;DR: New structures, synthesis, and bioactivity of Daphniphyllum alkaloids reported in recent years are presented and several inspired organic syntheses were completed.
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The caffeoylquinic acid-rich Pandanus tectorius fruit extract increases insulin sensitivity and regulates hepatic glucose and lipid metabolism in diabetic db/db mice
Chongming Wu,Xiaopo Zhang,Xue Zhang,Hong Luan,Guibo Sun,Xiaobo Sun,Xiaoliang Wang,Peng Guo,Xudong Xu +8 more
TL;DR: Overall, the CQA-rich PTF is beneficial for the treatment of diabetes and may alleviate hyperglycemia and dyslipidemia via activation of AMPK-AS160-GLUT4 pathway in skeletal muscles and inhibition of gluconeogenesis and lipogenesis in the liver.
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Elatoside C protects against hypoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes through the reduction of endoplasmic reticulum stress partially depending on STAT3 activation
Min Wang,Xiangbao Meng,Yingli Yu,Guibo Sun,Xudong Xu,Xiaopo Zhang,Xi Dong,Jingxue Ye,Huibo Xu,Yi-fan Sun,Xiaobo Sun +10 more
TL;DR: Results showed that Elatoside C (25 μM) treatment provided significant protection against H/R-induced cell death, as evidenced by improved cell viability, maintained mitochondrial membrane potential, diminished mitochondrial ROS, and reduced apoptotic cardiomyocytes.