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Xuefeng Niu
Researcher at Guangzhou Medical University
Publications - 31
Citations - 1050
Xuefeng Niu is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Virus & Antibody. The author has an hindex of 12, co-authored 22 publications receiving 711 citations.
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Journal ArticleDOI
Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients.
Baoqing Sun,Ying Feng,Xiaoneng Mo,Peiyan Zheng,Qian Wang,Pingchao Li,Ping Peng,Xiaoqing Liu,Zhilong Chen,Huimin Huang,Fan Zhang,Wenting Luo,Xuefeng Niu,Peiyu Hu,Longyu Wang,Hui Peng,Zhifeng Huang,Liqiang Feng,Feng Li,Fuchun Zhang,Fang Li,Nanshan Zhong,Ling Chen,Ling Chen +23 more
TL;DR: N and S specific IgM and IgG increased gradually after symptom onset and can be used for detection of SARS-CoV-2 infection.
Journal ArticleDOI
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques.
Liqiang Feng,Liqiang Feng,Qian Wang,Qian Wang,Chao Shan,Chenchen Yang,Ying Feng,Jia Wu,Liu Xiaolin,Yiwu Zhou,Ren-Di Jiang,Peiyu Hu,Xinglong Liu,Fan Zhang,Pingchao Li,Xuefeng Niu,Yichu Liu,Xuehua Zheng,Jia Luo,Jing Sun,Yingying Gu,Bo Liu,Yongcun Xu,Chufang Li,Weiqi Pan,Jincun Zhao,Changwen Ke,Xinwen Chen,Tao Xu,Nanshan Zhong,Guan Suhua,Zhiming Yuan,Ling Chen,Ling Chen +33 more
TL;DR: A replication-incompetent adenovirus based vaccine expressing SARS-CoV-2 spike is generated, protection from infection in non-human primates is shown, and the immune response after intramuscular and intranasal vaccination is analyzed.
Journal ArticleDOI
Visualizing influenza virus infection in living mice
Weiqi Pan,Zhenyuan Dong,Feng Li,Feng Li,Weixu Meng,Weixu Meng,Liqiang Feng,Xuefeng Niu,Chufang Li,Qinfang Luo,Zhengfeng Li,Caijun Sun,Ling Chen,Ling Chen +13 more
TL;DR: This work reports the visualization of influenza viral infection in living mice using an engineered replication-competent influenza A virus carrying luciferase reporter gene to enable real-time study of influenza virus infection and effects of antiviral therapeutics in living animals.
Journal ArticleDOI
Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients.
Xuefeng Niu,Li Song,Pingchao Li,Wenjing Pan,Qian Wang,Ying Feng,Xiaoneng Mo,Qihong Yan,X.L. Ye,Jia Luo,Linbing Qu,Daniel Weber,Miranda Byrne-Steele,Zhe Wang,Yu Fengjia,Fang Li,Richard M. Myers,Michael T. Lotze,Nanshan Zhong,Jian Han,Ling Chen,Ling Chen +21 more
TL;DR: Profound changes in T cell homeostasis raise critical questions about the early events in COVID-19 infection and demonstrate that immune repertoire analysis is a promising method for evaluating emergent host immunity to SARS-CoV-2 viral infection.
Journal ArticleDOI
Potent neutralizing monoclonal antibodies against Ebola virus infection.
Qi Zhang,Miao Gui,Xuefeng Niu,Shihua He,Ruoke Wang,Yupeng Feng,Andrea Kroeker,Andrea Kroeker,Yanan Zuo,Hua Wang,Ying Wang,Jiade Li,Chufang Li,Yi Shi,Xuanling Shi,George F. Gao,Ye Xiang,Xiangguo Qiu,Xiangguo Qiu,Ling Chen,Ling Chen,Linqi Zhang +21 more
TL;DR: In this article, neutralizing monoclonal antibodies against the surface glycoprotein (GP) of Ebola virus identified in West Africa in 2014 through sequential immunization of Chinese rhesus macaques and antigen-specific single B cell sorting were presented.