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Yann Duroc
Researcher at Paris-Sorbonne University
Publications - 16
Citations - 737
Yann Duroc is an academic researcher from Paris-Sorbonne University. The author has contributed to research in topics: Peptide deformylase & Cytoplasmic male sterility. The author has an hindex of 12, co-authored 16 publications receiving 617 citations. Previous affiliations of Yann Duroc include Institut national de la recherche agronomique & Agro ParisTech.
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Journal ArticleDOI
The preprophase band of microtubules controls the robustness of division orientation in plants
Estelle Schaefer,Katia Belcram,Magalie Uyttewaal,Yann Duroc,Magali Goussot,David Legland,Elise Laruelle,Elise Laruelle,Marie-Ludivine de Tauzia-Moreau,Martine Pastuglia,David Bouchez +10 more
TL;DR: This work characterized an Arabidopsis trm (TON1 Recruiting Motif) mutant that impairs PPB formation but does not affect interphase microtubules and shows that a main output of this microtubule array is to limit spindle rotations in order to increase the robustness of cell division.
Journal ArticleDOI
A protein phosphatase 2A complex spatially controls plant cell division
Lara Spinner,Astrid Gadeyne,Katia Belcram,Magali Goussot,Michaël Moison,Yann Duroc,Dominique Eeckhout,Nancy De Winne,Estelle Schaefer,Eveline Van De Slijke,Geert Persiau,Erwin Witters,Kris Gevaert,Geert De Jaeger,David Bouchez,Daniël Van Damme,Martine Pastuglia +16 more
TL;DR: A protein complex that targets protein phosphatase 2A activity to microtubules, regulating the transition from the interphase to the premitotic microtubule array is described, revealing an evolutionary link between the cortical cytoskeleton of plant cells and micro Tubule organizers in other eukaryotes.
Journal ArticleDOI
The Arabidopsis TRM1–TON1 Interaction Reveals a Recruitment Network Common to Plant Cortical Microtubule Arrays and Eukaryotic Centrosomes
Stéphanie Drevensek,Magali Goussot,Yann Duroc,Anna Christodoulidou,Sylvie Steyaert,Estelle Schaefer,Evelyne Duvernois,Olivier Grandjean,Marylin Vantard,David Bouchez,Martine Pastuglia +10 more
TL;DR: A novel superfamily of 34 proteins conserved in land plants, the TON1 Recruiting Motif (TRM) proteins, which share six short conserved motifs, including a Ton1-interacting motif present in all TRMs are identified, suggest conservation of eukaryotic centrosomal components in plant cells.
Journal ArticleDOI
Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.
Adrien Boularot,Carmela Giglione,Sylvain Petit,Yann Duroc,Rodolphe Alves de Sousa,Valéry Larue,Thierry Cresteil,Frédéric Dardel,Isabelle Artaud,Thierry Meinnel +9 more
TL;DR: A dual-screening strategy for selecting highly effective compounds with low inhibition effect against human PDF is developed and a new scaffold in vitro is selected that discriminated between human and bacterial PDFs.
Journal ArticleDOI
Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion.
Yann Duroc,Yann Duroc,Rajeev Kumar,Rajeev Kumar,Lepakshi Ranjha,Céline Adam,Céline Adam,Raphael Guerois,Khan Md Muntaz,Marie-Claude Marsolier-Kergoat,Marie-Claude Marsolier-Kergoat,Florent Dingli,Raphaelle Laureau,Raphaelle Laureau,Damarys Loew,Bertrand Llorente,Jean-Baptiste Charbonnier,Petr Cejka,Valérie Borde,Valérie Borde +19 more
TL;DR: It is shown that the budding yeast mismatch repair related MutLβ complex, Mlh1-Mlh2, specifically interacts with the conserved meiotic Mer3 helicase, which recruits it to recombination hotspots, independently of mismatch recognition, providing a mechanism for limiting gene conversion in vivo.