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Yuri A. Ushkaryov
Researcher at University of Kent
Publications - 60
Citations - 5989
Yuri A. Ushkaryov is an academic researcher from University of Kent. The author has contributed to research in topics: Latrotoxin & Exocytosis. The author has an hindex of 36, co-authored 59 publications receiving 5523 citations. Previous affiliations of Yuri A. Ushkaryov include Imperial College London & Medway School of Pharmacy.
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Journal ArticleDOI
Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.
Yuri A. Ushkaryov,Alexander G. Petrenko,Alexander G. Petrenko,Martin Geppert,Martin Geppert,Thomas C. Südhof,Thomas C. Südhof +6 more
TL;DR: The polymorphic structure of the neurexins, their neural localization, and their sequence similarity to proteins associated with neurogenesis suggest a function as cell recognition molecules in the nerve terminal.
Journal ArticleDOI
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
Harvey T. McMahon,Yuri A. Ushkaryov,Lisa Edelmann,E. Link,Thomas Binz,Heiner Niemann,Reinhard Jahn,Thomas C. Südhof +7 more
TL;DR: The results suggest that constitutive and regulated vesicular pathways use homologous proteins for membrane trafficking, probably for membrane fusion at the plasma membrane, indicating a greater mechanistic and evolutionary similarity between these pathways than previously thought.
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Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons
TL;DR: Characterization of many independent bovine neurexin I alpha cDNAs suggests that different splice sites are used independently, which potentially represents a third mechanism for creating a large number of cell surface receptors that are expressed by specific subsets of cells.
Journal ArticleDOI
Structure of a novel InsP3 receptor.
TL;DR: The results demonstrate the presence of several types of InsP3 receptor in brain and raise the possibility that intracellular Ca2+ signaling may involve multiple pathways with different regulatory properties dependent on different InsP 3 receptors.
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International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
Jörg Hamann,Gabriela Aust,Demet Araç,Felix B. Engel,Caroline J. Formstone,Robert Fredriksson,Randy A. Hall,Breanne L. Harty,Christiane Kirchhoff,Barbara Knapp,Arunkumar Krishnan,Ines Liebscher,Hsi-Hsien Lin,David C. Martinelli,Kelly Monk,Miriam C. Peeters,Xianhua Piao,Simone Prömel,Torsten Schöneberg,Thue W. Schwartz,Kathleen Singer,Martin Stacey,Yuri A. Ushkaryov,Mario Vallon,Uwe Wolfrum,Mathew W. Wright,Lei Xu,Tobias Langenhan,Helgi B. Schiöth +28 more
TL;DR: This review covers all major biologic aspects of Adhesion GPCRs, including evolutionary origins, interaction partners, signaling, expression, physiologic functions, and therapeutic potential.