Z
Zarko V. Boskovic
Researcher at University of Kansas
Publications - 32
Citations - 1665
Zarko V. Boskovic is an academic researcher from University of Kansas. The author has contributed to research in topics: Cancer cell & Piperlongumine. The author has an hindex of 12, co-authored 30 publications receiving 1113 citations. Previous affiliations of Zarko V. Boskovic include Howard Hughes Medical Institute & Harvard University.
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Journal ArticleDOI
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan,Matthew J. Ryan,Harshil Dhruv,Shubhroz Gill,Ossia M. Eichhoff,Brinton Seashore-Ludlow,Samuel D. Kaffenberger,John K. Eaton,Kenichi Shimada,Andrew J. Aguirre,Andrew J. Aguirre,Srinivas R. Viswanathan,Srinivas R. Viswanathan,Shrikanta Chattopadhyay,Pablo Tamayo,Pablo Tamayo,Wan Seok Yang,Matthew G. Rees,Sixun Chen,Zarko V. Boskovic,Sarah Javaid,Cherrie Huang,Xiaoyun Wu,Yuen-Yi Tseng,Elisabeth Roider,Dong Gao,James M. Cleary,Brian M. Wolpin,Jill P. Mesirov,Jill P. Mesirov,Daniel A. Haber,Daniel A. Haber,Jeffrey A. Engelman,Jesse S. Boehm,Joanne Kotz,Cindy S. Hon,Yu Chen,William C. Hahn,William C. Hahn,Mitchell P. Levesque,John G. Doench,Michael E. Berens,Alykhan F. Shamji,Paul A. Clemons,Brent R. Stockwell,Stuart L. Schreiber,Stuart L. Schreiber,Stuart L. Schreiber +47 more
TL;DR: Vulnerability to ferroptic cell death induced by inhibition of a lipid peroxidase pathway as a feature of therapy-resistant cancer cells across diverse mesenchymal cell-state contexts is identified.
Journal ArticleDOI
(BDP)CuH: a "hot" Stryker's reagent for use in achiral conjugate reductions.
TL;DR: A ligand-modified, economical version of Stryker's reagent (SR) has been developed based on a bidentate, achiral bis-phosphine that smoothly effects conjugate reductions of a variety of unsaturated substrates, including those that are normally unreactive toward SR.
Journal ArticleDOI
CuH-Catalyzed Enantioselective 1,2-Reductions of α,β-Unsaturated Ketones
TL;DR: The first study on a general technology for arriving at valued nonracemic allylic alcohols using asymmetric ligand-accelerated catalysis by copper hydride is described.
Journal ArticleDOI
Synthesis of Activated Alkenylboronates from Acetylenic Esters by CuH-Catalyzed 1,2-Addition/Transmetalation
Journal ArticleDOI
Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death.
Drew J. Adams,Zarko V. Boskovic,Jimmy R. Theriault,Alex J. Wang,Andrew M. Stern,Bridget K. Wagner,Alykhan F. Shamji,Stuart L. Schreiber +7 more
TL;DR: It is suggested that cancer cell lines are more resilient to chemically induced increases in ROS levels than previously thought and highlight electrophilicity as a property that may be more closely associated with cancer-selective cell death than ROS elevation.