Centro de Investigación y Desarrollo Tecnológico en Electroquímica

About: Centro de Investigación y Desarrollo Tecnológico en Electroquímica is a based out in . It is known for research contribution in the topics: Cyclic voltammetry & Catalysis. The organization has 537 authors who have published 682 publications receiving 10382 citations. The organization is also known as: Centro de Investigacion y Desarrollo Tecnologico en Electroquimica & Center of Research and Technologic Development in Electrochemistry.

Essential Metal-based drugs: Correlation between Redox Potential and Biological Activity of M2+ with a N2O2 Ligand

Abstract: One of the major public health problems worldwide is cancer followed by a significant number of deaths due to the resistance developed by bacteria or protozoan to the currently employed treatments. This generates an immediate need to develop drugs to treat these afflictions (illnesses, diseases). It has recently been identified that tumor cell, bacteria or protozoa are quite sensitive to oxidative stress induced by the same drugs. Due to this, it is important to develop new drugs to attend them, in this case, by using metals to increase the concentration of oxidative species. In the present work, the ligand 2,9-diformyl-4,7-diphenyl-1,10-phenanthroline and its corresponding coordination compounds with essential metals such as iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) were synthesized. The electrochemical study shows that these compounds present three redox processes, all of them associated to the ligand. The compounds have shown inhibitory activity in vitro against human neuroblastoma CHP-212 cells, Escherichia coli and trophozoites of Entamoeba histolytica HM1:IMSS. It has been found that the inhibitory activity of the compounds studied is related to the first reduction process of the ligand. The correlation between the inhibitory activity and the red ox potential was linear. The inhibitory activity in CHP-212 increased with the increase of the compounds’ redox potential values, in contrast with the behavior observed in Escherichia coli, where the compounds with lowest redox potential values have had significantly higher inhibitory activity. Many of these coordination compounds have shown a higher inhibitory activity than those typically used in the treatment of cancer (cisplatin). The next step is to prove these compounds in vitro against healthy cells in order to verify its selectivity or cytotoxicity in these systems.

Flow Analysis Based on Cathodic Current Using Different Designs of Channel Distribution In PEM Fuel Cells

Abstract: In this work, a physical and numerical simulation of cathodic current for different designs of the channel distribution in PEM fuel cells was carried out. The first design consisted serpentine-type channels with abrupt changes in flow direction. On the other hand, Designs 2 and 3 were made of serpentine channels with a more gradual change in flow direction. The fourth design was a crisscross-type channel, which was based on continually redirecting the flow, while Design 5 was made with straight parallel channels. Designs 1–3 had one intake, while Designs 4 and 5 had three. The latter two produced more uniform electrical current distributions than Designs 1–3. It can be concluded that the intakes situated effectively within each design were as important as the shape of the channel configuration. Finally, the parallel channel flow field (Design 5) was the best alternative for current collectors due to its better performance.

Contrast Enhancement Based on a Morphological Rational Multiscale Algorithm

Abstract: Resumen en: Contrast enhancement is an important task in image processing and it is commonly used as a preprocessing step in order to improve the results for other t...