Dicle University

About: Dicle University is a education organization based out in Diyarbakır, Turkey. It is known for research contribution in the topics: Population & Catalysis. The organization has 3007 authors who have published 6368 publications receiving 94797 citations. The organization is also known as: Dicle Üniversitesi & Zanîngeha Dîcleyê.

The Effects of Monocrotophos to Different Tissues of Freshwater Fish Cirrhinus mrigala

Abstract: The histopathological effects of monocrotophos on the gill, kidney and intestine tissues of the Cirrhinus mrigala were determined by light microscopy. The changes in the gills were characterized by epithelial hyperplasia, aneurysm, epithelial necrosis, desquamation, epithelial lifting, oedema, lamellar fusion and curling of secondary lamellae. Pycnotic nuclei in tubular epithelium, hypertrophied epithelial cells of renal tubules, contraction of the glomerulus and expansion of space inside the Bowman's capsule were observed in the kidney tissues of fish after exposure to monocrotophos. In the intestine tissues of fish exposed to monocrotophos, oedema, necrosis and atrophy of epithelial cells were observed.

Prognostic factors and clinical outcome of patients with Ewing’s sarcoma family of tumors in adults: multicentric study of the Anatolian Society of Medical Oncology

Abstract: The aim of this study was to evaluate prognostic factors, survival rate and the efficacy of the treatment modalities used in patients with Ewing sarcoma family of tumors (ESFT). Data of patients with ESFTs followed up at different cancer centers in Turkey between 2001 and 2010 were retrospectively analyzed. The median age of 114 patients was 26 years (range 14–66). The median follow-up was 20 months (range 1–118 months). Tumor size was between 1.5 and 14 cm (median 8 cm). Eighty-six percent of patients had localized disease at presentation, and 14 % had metastatic disease. Local therapy was surgery alone in 31 % of patients, surgery combined with radiotherapy in 41 % and radiotherapy alone in 18 %. Approximately 70 % of patients were treated with vincristine, doxorubicin, cyclophosphamide and actinomycin-D, alternating with ifosfamide and etoposide every 3 weeks. In patients with localized disease at presentation, the 5-year disease-free survival and overall survival were 60 and 65 %, respectively. At univariate analysis, patients with tumor size ≥8 cm, high serum lactate dehydrogenase, metastasis at presentation, poor histological response to chemotherapy and positive surgical margin had significantly worse event-free survival. The significant predictors of worse overall survival at univariate analysis were tumor size ≤8 cm, high lactate dehydrogenase, metastasis at presentation, poor histological response to chemotherapy, radiotherapy only as local treatment and positive surgical margin. ESFTs are aggressive tumors with a high incidence of local recurrence and distant metastasis. Multimodality treatment consisting of adequate surgical resection, aggressive chemotherapy (VAC alternating with IE) and radiotherapy is recommended for patients with ESFTs.

Adsorption of basic dyestuffs from aqueous solution by modified chitosan

Abstract: The capability of chitosan to adsorb the basic dyestuffs is very low. For this purpose, chitosan was modified to increase its adsorption capability with some cyclic acid anhydrides in dimethyl sulfoxide. Then, chitosan and its derivatives, chitosan modified with maleic anhydride (CMA), chitosan modified with phthalic anhydride (CPA), and chitosan modified with trimellitic anhydride (CTA), were compared according to their capabilities to remove brilliant green (BG) and methylene blue (MB) from aqueous solution. It was determined that CTA adsorbed much more BG and MB. The 70.57% of BG (C o: 50 ppm) and 71.86% of MB (C o: 50 ppm) in the samples of 50 mL by 0.1 g CTA were adsorbed at room temperature and at a shaking rate of 140 rpm within 24 h. As a result of this, the adsorption of BG and MB by CTA was kinetically investigated as dependent on temperature and pH. Besides, the adsorption isotherms of each dyestuff by CTA were determined at different temperatures. Then, some kinetical and thermodynami...

The relationship of the mean platelet volume and C-reactive protein levels with mortality in ischemic stroke patients

Abstract: BACKGROUND AND OBJECTIVES: The relationship of the mean platelet volume (MPV) and C-reactive protein (CRP) values with mortality in patients with ischemic stroke is not clear. Besides, the correlation between CRP and MPV in patients with ischemic stroke has not been adequately stud - ied yet. In the present study, our aim is to investigate the interrelationship of the CRP and MPV parame - ters together with their influence on mortality in pa - tients with acute ischemic stroke. PATIENTS AND METHODS : Sixty-three patients with acute ischemic stroke have been enrolled in the study. The stroke patients were divided into 2 groups as those who died within the first 10 days and those who survived.The MPV and CRP in both groups have been compared. Also, the MPV ob - tained from the ischemic stroke patients were com - pared with the MPV of the healthy volunteers. RESULTS : A statistically significant difference ( p = 0.027) was observed between the MPV of the stroke patients (8.6±1.95 fL) and the control group (7.93±0.82 fl). The MPV (9.24±1.98 fL) and CRP (10.8±7.0 mg/l) of those ischemic stroke patients who died were statistically significantly higher ( p < 0.05) than the MPV (8.09±1.75 fl) and CRP (3.2±3.5 mg/l) of the patients who survived. There was also a positive correlation between the MPV and CRP of the ischemic stroke patients (r = 0.31, p = 0.029). CONCLUSIONS : The fact that there is a rela - tionship between the MPV and CRP in ischemic stroke patients and that the CRP and MPV are higher in the ischemic stroke patients who died in comparison to those who survived may be an indication of the roles these markers play in the mortality of stroke patients.