Dicle University

About: Dicle University is a education organization based out in Diyarbakır, Turkey. It is known for research contribution in the topics: Population & Catalysis. The organization has 3007 authors who have published 6368 publications receiving 94797 citations. The organization is also known as: Dicle Üniversitesi & Zanîngeha Dîcleyê.

Classıfıcation of sleep apnea by using wavelet transform and artificial neural networks

Abstract: This paper describes a new method to classify sleep apnea syndrome (SAS) by using wavelet transforms and an artificial neural network (ANN). The network was trained and tested for different momentum coefficients. The abdominal respiration signals are separated into spectral components by using multi-resolution wavelet transforms. These spectral components are applied to the inputs of the artificial neural network. Then the neural network was configured to give three outputs to classify the SAS situation of the patient. The apnea can be broadly classified into three types: obstructive sleep apnea (OSA), central sleep apnea (CSA) and mixed sleep apnea (MSA). During OSA, the airway is blocked while respiratory efforts continue. During CSA the airway is open, however, there are no respiratory efforts. In this paper we aim to classify sleep apnea in one of three basic types: obstructive, central and mixed.

Serum cytokine and pro-brain natriuretic peptide (BNP) levels in patients with migraine.

Abstract: Objective: Although mi- graine has been related with an increased risk for ischemic stroke and cardiovascular events, there is insufficient data for role of pro-brain natriuretic peptide (pro-BNP) in migraine. In present case-control study, serum levels of pro-inflammatory (TNF-α, IL-1β and IL-6) and anti-inflammatory cytokines (IL-2, and IL-10) of migraine patients were investigated to deter- mine the role of cytokines and pro-BNP in mi- graine. Patients and Methods: Sixty-four consecu- tive newly diagnosed migraine patients and 34 healthy controls were enrolled. Serum TNF-α, IL- 1β, IL-2, IL-6, IL-10 and pro-BNP levels were mea- sured by using a chemiluminescence assay. Results: Migraine patients had significantly higher concentrations of IL-1β and IL-6 com- pared with the healthy controls (for IL-1β; 5.73 ± 1.44 vs. 4.90±1.40 pg/mL, respectively, p =0.006; for IL-6; 3.1±1.44 vs. 2.40±0.22 pg/mL, respec- tively, p =0.007). The mean IL-10 levels were found to be significantly lower in migraine pa- tients (3.38±2.93 pg/mL) than controls (6.76 ± 1.48 pg/mL) (p =0.007). There were no differ- ences in TNF-α (27.2±48.1 vs. 15.4±0.7) and IL-2 (1017±661 vs. 1153±228) levels between pa- tients with migraine and healthy controls. Mi- graine patients had higher concentrations of pro-BNP compared with healthy controls (27.0 ± 28.0 versus 13.2±8.6, p =0.006). Conclusions: Migraine patients have higher serum IL-1β and IL-6 levels, and lower IL-10 levels than healthy subjects. These findings support that cytokines may be related to neu- rogenic inflammation in the pathogenesis of migraine. Also, increased pro-BNP may indi- cate to preclinical cardiac involvement in pa- tients with migraine.

The effects of fenvalerate on different tissues of freshwater fish Cirrhinus mrigala.

Abstract: The histopathological changes of fenvalerate on the gill, kidney, liver and intestine tissues of the Cirrhinus mrigala were determined by light microscopy. The fish were exposed to two sub-lethal concentrations of fenvalerate (1.5-3.0 ppb). The most common gill changes at all concentrations of fenvalerate were epithelial hyperplasia, epithelial necrosis, desquamation and lamellar fusion. Besides, epithelial lifting, oedema, swelling at the tips of secondary lamellae and curling of secondary lamellae were other histopathological changes. Necrosis of tubular epithelium, pycnotic nuclei in the hematopoietic tissue, hypertrophied epithelial cells of renal tubules, narrowing of the tubular lumen, expansion of space inside the Bowman's capsule and contraction of the glomerulus were observed in kidney tissues of fish. Hepatic lesions in the liver tissues of fish exposed to fenvalerate were characterized by congestion, cloudy swelling of hepatocytes and focal necrosis. Atrophy of epithelial cells, necrosis of epithelial cells, desquamation of mucosal epithelium and infiltration of lymphocytes into the lamina propria were detected in intestine tissues of fish after exposure to fenvalerate.