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Institution

Konkuk University

EducationSeoul, South Korea
About: Konkuk University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Apoptosis. The organization has 13405 authors who have published 27027 publications receiving 506313 citations.
Topics: Population, Apoptosis, Cancer, Graphene, Cancer cell


Papers
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Journal ArticleDOI
TL;DR: It is suggested that only aggregated forms of extracellular alpha-synuclein can be cleared by cell-mediated uptake and degradation, and this might represent a mechanism of preventing neurons from exposure to potentially toxic alpha- Synuclein.

455 citations

Journal ArticleDOI
TL;DR: Juxtaposed against widespread land application of wastewater treatment biosolids to food crops, these findings forewarn of agriculturally associated human and environmental risks from the accelerating use of MNMs.
Abstract: Based on previously published hydroponic plant, planktonic bacterial, and soil microbial community research, manufactured nanomaterial (MNM) environmental buildup could profoundly alter soil-based food crop quality and yield. However, thus far, no single study has at once examined the full implications, as no studies have involved growing plants to full maturity in MNM-contaminated field soil. We have done so for soybean, a major global commodity crop, using farm soil amended with two high-production metal oxide MNMs (nano-CeO2 and -ZnO). The results provide a clear, but unfortunate, view of what could arise over the long term: (i) for nano-ZnO, component metal was taken up and distributed throughout edible plant tissues; (ii) for nano-CeO2, plant growth and yield diminished, but also (iii) nitrogen fixation—a major ecosystem service of leguminous crops—was shut down at high nano-CeO2 concentration. Juxtaposed against widespread land application of wastewater treatment biosolids to food crops, these findings forewarn of agriculturally associated human and environmental risks from the accelerating use of MNMs.

451 citations

Journal ArticleDOI
TL;DR: The transverse momentum spectra of charged particles have been measured in pp and PbPb collisions at 2.76 TeV by the CMS experiment at the LHC as mentioned in this paper.
Abstract: The transverse momentum spectra of charged particles have been measured in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV by the CMS experiment at the LHC. In the transverse momentum range pt = 5-10 GeV/c, the charged particle yield in the most central PbPb collisions is suppressed by up to a factor of 5 compared to the pp yield scaled by the number of incoherent nucleon-nucleon collisions. At higher pt, this suppression is significantly reduced, approaching roughly a factor of 2 for particles with pt in the range pt=40-100 GeV/c.

446 citations

Journal ArticleDOI
TL;DR: The DONUT experiment has analyzed 203 neutrino interactions recorded in nuclear emulsion targets as discussed by the authors, with an estimated background of 0.34 events, consistent with the Standard Model expectation.

442 citations

Journal ArticleDOI
TL;DR: Evidence of antibacterial and anti-biofilm effects of A. cobbe-mediated synthesis of AgNPs and their enhanced capacity against various human pathogenic bacteria are presented to suggest thatAgNPs could be used as an adjuvant for the treatment of infectious diseases.
Abstract: Silver nanoparticles (AgNPs) have been used as antibacterial, antifungal, antiviral, anti-inflammtory, and antiangiogenic due to its unique properties such as physical, chemical, and biological properties. The present study was aimed to investigate antibacterial and anti-biofilm activities of silver nanoparticles alone and in combination with conventional antibiotics against various human pathogenic bacteria. Here, we show that a simple, reliable, cost effective and green method for the synthesis of AgNPs by treating silver ions with leaf extract of Allophylus cobbe. The A. cobbe-mediated synthesis of AgNPs (AgNPs) was characterized by ultraviolet-visible absorption spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), dynamic light scattering (DLS), and transmission electron microscopy (TEM). Furthermore, the antibacterial and anti-biofilm activity of antibiotics or AgNPs, or combinations of AgNPs with an antibiotic was evaluated using a series of assays: such as in vitro killing assay, disc diffusion assay, biofilm inhibition, and reactive oxygen species generation in Pseudomonas aeruginosa, Shigella flexneri, Staphylococcus aureus, and Streptococcus pneumonia. The results suggest that, in combination with antibiotics, there were significant antimicrobial and anti-biofilm effects at lowest concentration of AgNPs using a novel plant extract of A. cobbe, otherwise sublethal concentrations of the antibiotics. The significant enhancing effects were observed for ampicillin and vancomycin against Gram-negative and Gram-positive bacteria, respectively. These data suggest that combining antibiotics and biogenic AgNPs can be used therapeutically for the treatment of infectious diseases caused by bacteria. This study presented evidence of antibacterial and anti-biofilm effects of A. cobbe-mediated synthesis of AgNPs and their enhanced capacity against various human pathogenic bacteria. These results suggest that AgNPs could be used as an adjuvant for the treatment of infectious diseases.

441 citations


Authors

Showing all 13470 results

NameH-indexPapersCitations
Richard A. Flavell2311328205119
Hyun-Chul Kim1764076183227
Jovan Milosevic1521433106802
Jongmin Lee1502257134772
Byung-Sik Hong1461557105696
Ali Khademhosseini14088776430
Suyong Choi135149597053
Tae Jeong Kim132142093959
Maurizio Fava126101270636
Mihee Jo12580668740
Dooyeon Gyun12283667653
Dong Ho Moon11991267053
Sanghyeon Song11955656460
Louis J. Ignarro10633546008
Hans R. Schöler9537441150
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202330
2022114
20211,927
20201,932
20191,846
20181,752