Institution
Konkuk University
Education•Seoul, South Korea•
About: Konkuk University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Apoptosis. The organization has 13405 authors who have published 27027 publications receiving 506313 citations.
Topics: Population, Apoptosis, Cancer, Graphene, Cancer cell
Papers published on a yearly basis
Papers
More filters
••
14 Aug 2012
TL;DR: In this paper, a search for high-mass resonances decaying to electron or muon pairs has been performed using pp collision data collected at 7 TeV by the CMS experiment in 2011, and the event yields observed in the signal regions are consistent with predictions of the standard model backgrounds.
Abstract: A search for narrow, high-mass resonances decaying to electron or muon pairs has been performed using pp collision data collected at sqrt(s)=7 TeV by the CMS experiment in 2011. The data sample corresponds to an integrated luminosity of approximately 5 inverse femtobarns. The event yields observed in the signal regions are consistent with predictions of the standard model backgrounds, and upper limits on the cross section times branching fraction for a resonance decaying to dileptons are extracted from a shape analysis of the dilepton invariant mass distribution. The resulting mass limits at 95% confidence level are 2330 GeV for the Z' in the Sequential Standard Model, 2000 GeV for the superstring-inspired Z'(psi) resonance, 890 (540) GeV for the Stueckelberg extension Z'(St) with the mass parameter epsilon=0.06 (0.04), and 2140 (1810) GeV for Kaluza--Klein gravitons with the coupling parameter k/Mbar(Pl) of 0.10 (0.05). These limits are the most stringent to date.
110 citations
••
TL;DR: Data indicate that PD-MSC mediates neuroprotection by regulating neuronal death, neurogenesis, glia cell activation in hippocampus, and altering cytokine expression, suggesting a close link between the therapeutic effects of MSCs and the damaged CNS in Alzheimer’s disease.
Abstract: Mesenchymal stem cells (MSCs) promote functional recoveries in pathological experimental models of central nervous system (CNS) and are currently being tested in clinical trials for neurological disorders, but preventive mechanisms of placenta-derived MSCs (PD-MSCs) for Alzheimer's disease are poorly understood. Herein, we investigated the inhibitory effect of PD-MSCs on neuronal cell death and memory impairment in Aβ1–42-infused mice. After intracerebroventrical (ICV) infusion of Aβ1–42 for 14 days, the cognitive function was assessed by the Morris water maze test and passive avoidance test. Our results showed that the transplantation of PD-MSCs into Aβ1–42-infused mice significantly improved cognitive impairment, and behavioral changes attenuated the expression of APP, BACE1, and Aβ, as well as the activity of β-secretase and γ-secretase. In addition, the activation of glia cells and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were inhibited by the transplantation of PD-MSCs. Furthermore, we also found that PD-MSCs downregulated the release of inflammatory cytokines as well as prevented neuronal cell death and promoted neuronal cell differentiation from neuronal progenitor cells in Aβ1–42-infused mice. These data indicate that PD-MSC mediates neuroprotection by regulating neuronal death, neurogenesis, glia cell activation in hippocampus, and altering cytokine expression, suggesting a close link between the therapeutic effects of MSCs and the damaged CNS in Alzheimer's disease.
110 citations
••
TL;DR: In this paper, the feasibility of metal oxide assisted metal macrocyclic complex was investigated as a catalyst for ORR in an air-cathode MFC, and the results revealed that cobalt oxide (CoOx) incorporation increased the ORR activity of iron phthalocyanine (FePc).
110 citations
••
TL;DR: In this article, a new numerical algorithm suitable for determining adaptive dead time, and blocking automatic reclosing during permanent faults on overhead lines, is presented based on terminal voltage input data processing.
Abstract: This paper presents a new numerical algorithm suitable for determining adaptive dead time, and blocking automatic reclosing during permanent faults on overhead lines. It is based on terminal voltage input data processing. The decision if it is safe or not to reclose is determined by the voltage signal of faulted and tripped line phase using the total harmonic distortion factor calculated by discrete Fourier transform. The algorithm was successfully tested using signals recorded on the real power system. The tests demonstrate the ability of the presented algorithm to determine the secondary arc extinction time and to block unsuccessful automatic reclosing of high-voltage lines with permanent fault
110 citations
••
TL;DR: Overall, based on the physiological and molecular level responses, it was observed that exposure to silver nanoparticles exerted more toxic response than silver ions in A. thaliana.
Abstract: In this study, the effect of silver nanoparticles and silver ions on Arabidopsis thaliana was investigated at physiological and molecular levels. The seedlings were grown in sublethal concentrations of silver nanoparticles and silver ions (0.2, 0.5, and 1 mg/L) in 1/4 Hoagland’s medium for 14 days under submerged hydroponic conditions. Significantly higher reduction in the total chlorophyll and increase in anthocyanin content were observed after exposure to 0.5 and 1 mg/L silver nanoparticles as compared to similar concentrations of silver ions. Lipid peroxidation increased significantly after exposure to 0.2, 0.5, and 1 mg/L of silver nanoparticles and 0.5 and 1 mg/L of silver ions. Qualitative analysis with dichloro-dihydro-fluorescein diacetate and rhodamine 123 fluorescence showed a dose-dependent increase in reactive oxygen species production and changes in mitochondrial membrane potential in the roots of seedlings exposed to different concentrations of silver nanoparticles. Real-time PCR analysis showed significant upregulation in the expression of sulfur assimilation, glutathione biosynthesis, glutathione S-transferase, and glutathione reductase genes upon exposure to silver nanoparticles as compared with silver ions. Overall, based on the physiological and molecular level responses, it was observed that exposure to silver nanoparticles exerted more toxic response than silver ions in A. thaliana.
110 citations
Authors
Showing all 13470 results
Name | H-index | Papers | Citations |
---|---|---|---|
Richard A. Flavell | 231 | 1328 | 205119 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Jovan Milosevic | 152 | 1433 | 106802 |
Jongmin Lee | 150 | 2257 | 134772 |
Byung-Sik Hong | 146 | 1557 | 105696 |
Ali Khademhosseini | 140 | 887 | 76430 |
Suyong Choi | 135 | 1495 | 97053 |
Tae Jeong Kim | 132 | 1420 | 93959 |
Maurizio Fava | 126 | 1012 | 70636 |
Mihee Jo | 125 | 806 | 68740 |
Dooyeon Gyun | 122 | 836 | 67653 |
Dong Ho Moon | 119 | 912 | 67053 |
Sanghyeon Song | 119 | 556 | 56460 |
Louis J. Ignarro | 106 | 335 | 46008 |
Hans R. Schöler | 95 | 374 | 41150 |