Institution
Maryland Department of Health
Government•Baltimore, Maryland, United States•
About: Maryland Department of Health is a government organization based out in Baltimore, Maryland, United States. It is known for research contribution in the topics: Population & Public health. The organization has 106 authors who have published 100 publications receiving 7576 citations. The organization is also known as: Maryland Department of Health and Mental Hygiene.
Topics: Population, Public health, Men who have sex with men, Health care, Acquired immunodeficiency syndrome (AIDS)
Papers published on a yearly basis
Papers
More filters
••
Centers for Disease Control and Prevention1, Colorado Department of Public Health and Environment2, Oregon Health Authority3, University of Rochester4, Veterans Health Administration5, Yale University6, University of New Mexico7, Maryland Department of Health8, University of California, San Francisco9
TL;DR: In this article, the authors used regression models to calculate estimates of national incidence and total number of infections, first recurrences, and deaths within 30 days after the diagnosis of C. difficile infection.
Abstract: Background The magnitude and scope of Clostridium difficile infection in the United States continue to evolve. Methods In 2011, we performed active population- and laboratory-based surveillance across 10 geographic areas in the United States to identify cases of C. difficile infection (stool specimens positive for C. difficile on either toxin or molecular assay in residents ≥1 year of age). Cases were classified as community-associated or health care–associated. In a sample of cases of C. difficile infection, specimens were cultured and isolates underwent molecular typing. We used regression models to calculate estimates of national incidence and total number of infections, first recurrences, and deaths within 30 days after the diagnosis of C. difficile infection. Results A total of 15,461 cases of C. difficile infection were identified in the 10 geographic areas; 65.8% were health care–associated, but only 24.2% had onset during hospitalization. After adjustment for predictors of disease incidence, the estimated number of incident C. difficile infections in the United States was 453,000 (95% confidence interval [CI], 397,100 to 508,500). The incidence was estimated to be higher among females (rate ratio, 1.26; 95% CI, 1.25 to 1.27), whites (rate ratio, 1.72; 95% CI, 1.56 to 2.0), and persons 65 years of age or older (rate ratio, 8.65; 95% CI, 8.16 to 9.31). The estimated number of first recurrences of C. difficile infection was 83,000 (95% CI, 57,000 to 108,900), and the estimated number of deaths was 29,300 (95% CI, 16,500 to 42,100). The North American pulsed-field gel electrophoresis type 1 (NAP1) strain was more prevalent among health care–associated infections than among community-associated infections (30.7% vs. 18.8%, P<0.001) Conclusions C. difficile was responsible for almost half a million infections and was associated with approximately 29,000 deaths in 2011. (Funded by the Centers for Disease Control and Prevention.)
2,209 citations
••
Centers for Disease Control and Prevention1, United States Department of Health and Human Services2, Colorado Department of Public Health and Environment3, Yale University4, Veterans Health Administration5, Emory University6, Alabama Department of Public Health7, Maryland Department of Health8, New Mexico Department of Health9, New York State Department of Health10, University of Rochester11, Ohio Department of Health12, Vanderbilt University13, Lake County14
TL;DR: It is suggested that older adults have elevated rates of COVID-19-associated hospitalization and the majority of persons hospitalized with CO VID-19 have underlying medical conditions, which underscore the importance of preventive measures to protect older adults and persons with underlyingmedical conditions, as well as the general public.
Abstract: Since SARS-CoV-2, the novel coronavirus that causes coronavirus disease 2019 (COVID-19), was first detected in December 2019 (1), approximately 1.3 million cases have been reported worldwide (2), including approximately 330,000 in the United States (3). To conduct population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations in the United States, the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) was created using the existing infrastructure of the Influenza Hospitalization Surveillance Network (FluSurv-NET) (4) and the Respiratory Syncytial Virus Hospitalization Surveillance Network (RSV-NET). This report presents age-stratified COVID-19-associated hospitalization rates for patients admitted during March 1-28, 2020, and clinical data on patients admitted during March 1-30, 2020, the first month of U.S. surveillance. Among 1,482 patients hospitalized with COVID-19, 74.5% were aged ≥50 years, and 54.4% were male. The hospitalization rate among patients identified through COVID-NET during this 4-week period was 4.6 per 100,000 population. Rates were highest (13.8) among adults aged ≥65 years. Among 178 (12%) adult patients with data on underlying conditions as of March 30, 2020, 89.3% had one or more underlying conditions; the most common were hypertension (49.7%), obesity (48.3%), chronic lung disease (34.6%), diabetes mellitus (28.3%), and cardiovascular disease (27.8%). These findings suggest that older adults have elevated rates of COVID-19-associated hospitalization and the majority of persons hospitalized with COVID-19 have underlying medical conditions. These findings underscore the importance of preventive measures (e.g., social distancing, respiratory hygiene, and wearing face coverings in public settings where social distancing measures are difficult to maintain)† to protect older adults and persons with underlying medical conditions, as well as the general public. In addition, older adults and persons with serious underlying medical conditions should avoid contact with persons who are ill and immediately contact their health care provider(s) if they have symptoms consistent with COVID-19 (https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html) (5). Ongoing monitoring of hospitalization rates, clinical characteristics, and outcomes of hospitalized patients will be important to better understand the evolving epidemiology of COVID-19 in the United States and the clinical spectrum of disease, and to help guide planning and prioritization of health care system resources.
2,016 citations
••
Centers for Disease Control and Prevention1, University of California, Berkeley2, Anschutz Medical Campus3, Colorado Department of Public Health and Environment4, Yale University5, Veterans Health Administration6, Emory University7, United States Department of Veterans Affairs8, Alabama Department of Public Health9, Maryland Department of Health10, New Mexico Department of Health11, New York State Department of Health12, University of Rochester13, Ohio Department of Health14, Oregon Health Authority15, Vanderbilt University16, Lake County17, United States Department of Health and Human Services18
TL;DR: The cumulative rate of pediatric COVID-19-associated hospitalization remains low compared with that among adults, but weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults.
Abstract: Most reported cases of coronavirus disease 2019 (COVID-19) in children aged <18 years appear to be asymptomatic or mild (1). Less is known about severe COVID-19 illness requiring hospitalization in children. During March 1-July 25, 2020, 576 pediatric COVID-19 cases were reported to the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET), a population-based surveillance system that collects data on laboratory-confirmed COVID-19-associated hospitalizations in 14 states (2,3). Based on these data, the cumulative COVID-19-associated hospitalization rate among children aged <18 years during March 1-July 25, 2020, was 8.0 per 100,000 population, with the highest rate among children aged <2 years (24.8). During March 21-July 25, weekly hospitalization rates steadily increased among children (from 0.1 to 0.4 per 100,000, with a weekly high of 0.7 per 100,000). Overall, Hispanic or Latino (Hispanic) and non-Hispanic black (black) children had higher cumulative rates of COVID-19-associated hospitalizations (16.4 and 10.5 per 100,000, respectively) than did non-Hispanic white (white) children (2.1). Among 208 (36.1%) hospitalized children with complete medical chart reviews, 69 (33.2%) were admitted to an intensive care unit (ICU); 12 of 207 (5.8%) required invasive mechanical ventilation, and one patient died during hospitalization. Although the cumulative rate of pediatric COVID-19-associated hospitalization remains low (8.0 per 100,000 population) compared with that among adults (164.5),* weekly rates increased during the surveillance period, and one in three hospitalized children were admitted to the ICU, similar to the proportion among adults. Continued tracking of SARS-CoV-2 infections among children is important to characterize morbidity and mortality. Reinforcement of prevention efforts is essential in congregate settings that serve children, including childcare centers and schools.
429 citations
••
Agency for Healthcare Research and Quality1, Centers for Disease Control and Prevention2, American Foundation for AIDS Research3, Boston University4, Brown University5, Case Western Reserve University6, Council of State and Territorial Epidemiologists7, Dalhousie University8, Duke University9, Emory University10, Food and Drug Administration11, Gay Men's Health Crisis12, Rutgers University13, Harlem Hospital Center14, Harvard University15, Howard University16, Johns Hopkins University17, Maryland Department of Health18, Mount Auburn Hospital19, Icahn School of Medicine at Mount Sinai20, National Institutes of Health21, Northwestern University22, Rush University Medical Center23, St. Jude Children's Research Hospital24, Stony Brook University25, Tulane University26, University of Alabama27, University of Arizona28, University of California, San Francisco29, University of Minnesota30, University of Southern California31, University of Washington32, Washington University in St. Louis33
422 citations
••
TL;DR: To decrease HIV transmission, MSM should be encouraged to receive an HIV test at least annually, and prevention programs should improve means of reaching persons unaware of their HIV status, especially those in populations disproportionately at risk.
Abstract: Well into the third decade of the human immunodeficiency virus (HIV) epidemic, rates of HIV infection remain high, especially among minority populations. Of newly diagnosed HIV infections in the United States during 2003, CDC estimated that approximately 63% were among men who were infected through sexual contact with other men, 50% were among blacks, 32% were among whites, and 16% were among Hispanics. Studies of HIV infection among young men who have sex with men (MSM) in the mid to late 1990s revealed high rates of HIV prevalence, incidence, and unrecognized infection, particularly among young black MSM. To reassess those findings and previous HIV testing behaviors among MSM, CDC analyzed data from five of 17 cities participating in the National HIV Behavioral Surveillance (NHBS) system. This report summarizes preliminary findings from the HIV-testing component of NHBS, which indicated that, of MSM surveyed, 25% were infected with HIV, and 48% of those infected were unaware of their infection. To decrease HIV transmission, MSM should be encouraged to receive an HIV test at least annually, and prevention programs should improve means of reaching persons unaware of their HIV status, especially those in populations disproportionately at risk.
312 citations
Authors
Showing all 106 results
Name | H-index | Papers | Citations |
---|---|---|---|
Liza Solomon | 31 | 64 | 4009 |
Patricia Ryan | 27 | 74 | 4643 |
Lucy E. Wilson | 24 | 59 | 7972 |
Colin Flynn | 24 | 58 | 2005 |
Joshua M. Sharfstein | 23 | 155 | 2786 |
David Blythe | 20 | 41 | 1883 |
Clifford S. Mitchell | 17 | 44 | 1010 |
Maya Monroe | 14 | 27 | 2407 |
Kenneth A. Feder | 13 | 33 | 898 |
Susan R. Panny | 10 | 10 | 1020 |
S. Bur | 10 | 11 | 686 |
W. A. Cronin | 8 | 11 | 564 |
Alvina Chu | 8 | 11 | 593 |
Julia Hidalgo | 6 | 7 | 434 |
Maria A. Said | 6 | 9 | 146 |