Institution
New York Methodist Hospital
Healthcare•Brooklyn, New York, United States•
About: New York Methodist Hospital is a healthcare organization based out in Brooklyn, New York, United States. It is known for research contribution in the topics: Myocardial infarction & Percutaneous coronary intervention. The organization has 948 authors who have published 936 publications receiving 29954 citations.
Topics: Myocardial infarction, Percutaneous coronary intervention, Population, Conventional PCI, Heart failure
Papers published on a yearly basis
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TL;DR: The preponderance of evidence suggests that stimulants other than bupropion are safe and effective in the treatment of attention deficit disorder in children with epilepsy, although controlled studies of dextroamphetamine in this population are lacking.
136 citations
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TL;DR: Between 1993 and 2004, significant variability has occurred in ED management of acute allergic reactions, especially histamine, blockers and inhaled beta-agonists.
Abstract: Background The clinical epidemiology of acute allergic reactions in the emergency department (ED) is uncertain. Objectives To characterize ED visits for acute allergic reactions and to evaluate national trends in ED management. Methods The National Hospital Ambulatory Medical Care Survey was used to identify a nationally representative sample of ED visits between 1993 and 2004. Cases with a diagnosis of acute allergic reaction were identified by International Classification of Diseases, Ninth Revision (ICD-9) codes (9950, 9951, 9952, 9953, 9956). Results A total of 12.4 million allergy-related ED visits occurred from 1993 to 2004, representing 1.0% (95% confidence interval, 0.93%-1.10%) of all ED visits or 1.03 million ED visits per year. The number of allergy-related ED visits remained relatively stable, averaging 3.8 per 1,000 US population per year (95% confidence interval, 3.4–4.1; P for trend=.39). Although 63% of all visits were coded as urgent, only 4% required hospitalization. Anaphylaxis coding was rare (1%). ED staff prescribed medications in 87% of visits, especially histamine 1 blockers (62%; P for trend=.29). Increases were noted from 1993 to 2004 for corticosteroids (22% to 50%; P 2 blockers (7% to 18%; P P = .008). Epinephrine use was infrequent and declining (19% to 7%; P = .04). Conclusion Between 1993 and 2004, significant variability has occurred in ED management of acute allergic reactions.
133 citations
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TL;DR: In this SCD population, abnormal BMD seemed to be independent of sex, age and menopause, whereas BMI, ferritin level, Hb type and level appeared to play a major role.
Abstract: Summary Sickle cell disease (SCD) leads to many complications including osteoporosis and osteopenia. We studied the prevalence and predisposing factors of low bone mass density (BMD) in adults with SCD. In this retrospective study, dual X-ray absorptiometry bone scans were used to determine BMD in the lumbar spine, femoral neck and ultra distal radius of 103 patients (73 females, 30 males, aged 15‐80 years). Chart reviews and a patient questionnaire were used to collect patient characteristics, disease course and severity, and low BMD risk factors. The 79AE6% of patients (mean age 36AE 5±1 2AE5 years) had an abnormal BMD, with a predilection for the lumbar spine (P ¼ 0AE001). Analysis by 3 (low BMD versus very low BMD versus normal) or by 2 groups (abnormal versus normal) showed that abnormal BMD was associated with lower body mass index (BMI) (P ¼ 0AE003), lower Hb level (P ¼ 0AE001) and higher ferritin (P ¼ 0AE003). Low BMD patients were more likely to be SS, SC or Sb 0 thal than Sb + thal (P ¼ 0AE022). Abnormal BMD was not related to age, sex, menarche, SCD complications, number of crises, iron overload, treatment with hydroxycarbamide or desferal, renal disease, smoking or alcohol. Patients treated with hydroxycarbamide for at least 6 months were more likely to have an abnormal BMD. In this SCD population, abnormal BMD seemed to be independent of sex, age and menopause, whereas BMI, ferritin level, Hb type and level appeared to play a major role.
132 citations
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TL;DR: One of the many systematic approaches to interpreting CXRs is outlined and the lesions that are commonly missed are highlights and the limitations of CXR are described.
132 citations
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University of Alabama at Birmingham1, Thammasat University2, Tufts University3, Nationwide Children's Hospital4, Mayo Clinic5, University of Adelaide6, Johns Hopkins University7, Tel Aviv University8, University of Colorado Denver9, Tel Aviv Sourasky Medical Center10, North Shore-LIJ Health System11, Medical College of Wisconsin12, Kaiser Permanente13, New York Methodist Hospital14, University of Washington15, Boston Children's Hospital16, Memorial Hospital of South Bend17, Complutense University of Madrid18, University Hospital of Wales19, Sheba Medical Center20, Veterans Health Administration21, Alfred I. duPont Hospital for Children22, St. Joseph's Hospital and Medical Center23, Ghent University24, University of Pennsylvania25, Duke University26, Wayne State University27, University of Rochester28, Translational Genomics Research Institute29, Hackensack University Medical Center30, University of Tennessee Health Science Center31, University of North Carolina at Chapel Hill32, University of Southern California33, Pontifícia Universidade Católica do Paraná34, Yale University35, Baylor College of Medicine36, University of Texas Southwestern Medical Center37, University of Cincinnati38, Rowan University39, Children's Hospitals and Clinics of Minnesota40, University of Chicago41, University of Florida42, Oregon Health & Science University43, Katholieke Universiteit Leuven44
TL;DR: 136 individuals with a distinct phenotype carrying one of five different NF1 missense mutations affecting p.Arg1809 affect 1.23% of unrelated NF1 probands in the UAB cohort, therefore this specific NF1 genotype–phenotype correlation will affect counseling and management of a significant number of patients.
Abstract: Neurofibromatosis type 1 (NF1) is one of the most frequent genetic disorders, affecting 1:3,000 worldwide. Identification of genotype–phenotype correlations is challenging because of the wide range clinical variability, the progressive nature of the disorder, and extreme diversity of the mutational spectrum. We report 136 individuals with a distinct phenotype carrying one of five different NF1 missense mutations affecting p.Arg1809. Patients presented with multiple cafe-au-lait macules (CALM) with or without freckling and Lisch nodules, but no externally visible plexiform neurofibromas or clear cutaneous neurofibromas were found. About 25% of the individuals had Noonan-like features. Pulmonic stenosis and short stature were significantly more prevalent compared with classic cohorts (P < 0.0001). Developmental delays and/or learning disabilities were reported in over 50% of patients. Melanocytes cultured from a CALM in a segmental NF1-patient showed two different somatic NF1 mutations, p.Arg1809Cys and a multi-exon deletion, providing genetic evidence that p.Arg1809Cys is a loss-of-function mutation in the melanocytes and causes a pigmentary phenotype. Constitutional missense mutations at p.Arg1809 affect 1.23% of unrelated NF1 probands in the UAB cohort, therefore this specific NF1 genotype–phenotype correlation will affect counseling and management of a significant number of patients.
130 citations
Authors
Showing all 953 results
Name | H-index | Papers | Citations |
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Manish Sharma | 82 | 1407 | 33361 |
Vic Hasselblad | 80 | 215 | 24087 |
Alan B. Lumsden | 69 | 490 | 16111 |
Kutluk Oktay | 68 | 261 | 16787 |
David J. Whellan | 60 | 269 | 16592 |
James C. Fang | 59 | 275 | 20075 |
Ralph Green | 54 | 228 | 10318 |
Sorin J. Brener | 47 | 266 | 13534 |
Ralph Carmel | 46 | 139 | 6949 |
S. Chiu Wong | 45 | 165 | 11468 |
O. Wayne Isom | 45 | 102 | 7446 |
Martin Möckel | 43 | 286 | 7630 |
Narong Kulvatunyou | 37 | 217 | 4691 |
Moshe Schein | 35 | 164 | 4528 |
Leslie Wise | 35 | 234 | 4783 |