Suffolk University

About: Suffolk University is a education organization based out in Boston, Massachusetts, United States. It is known for research contribution in the topics: Population & Sugar beet. The organization has 6462 authors who have published 9321 publications receiving 235328 citations.

Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years on.

Abstract: Summary Aims: This short report was designed to provide 2-year follow-up data from a previous study carried out in a primary care practice in the UK to assess the clinical and practical implications of switching to generic drugs. Methods: All patients previously switched from atorvastatin to simvastatin or losartan to candesartan were reviewed retrospectively 2 years after the switch. Total serum cholesterol and clinic blood pressure readings were used along with records of cardiovascular events occuring during the 2 year period to assess the clinical impact of the switch. Results: Of the 69 patients switched from atorvastatin to simvastatin between March and September 2005, 65 are still registered at the practice. Of these, 61 (94%) are still on simvastatin and 58 (89%) on the same dose. There was no significant change in mean total cholesterol over this 2 year period [between 4.04 ± 0.52 mmol/l prior to the switch and 3.90 ± 0.63 mmol/l 2 years after the switch (p = 0.06)]. Of the 108 patients switched from losartan to candesartan, 94 are still registered at the practice and taking an angiotensin receptor blocker (ARB), 92 of these (98%) are still on candesartan and there was a significant reduction in blood pressure 2 years post-switch [between 138/79 ± 12.9/6.6 prior to the switch and 131/77 ± 13.1/7.6 mmHg 2 years after the switch (p<<0.05)]. No adverse events attributable to the switch were reported in either group. Conclusion: This small study provides evidence that switching drugs in primary care can be cost effective and safe in the medium term, if care is taken with selection of patients and there is structured follow-up in place.

Pumping device having inlet and outlet valves adjacent opposed sides of a tube deforming device

Abstract: A pumping device controlling an amount of liquid passing through a length of tubing accommodated in the pumping device. The pumping device includes inlet and outlet valves located adjacent opposed sides of a tube deforming device. The valves are controllable for restricting the flow of liquid through the tubing, and the deforming device is such that the tubing is first deformed in one direction and then in another direction which tends to restore the original cross-sectional shape of the tubing.

A Comparison of Pimp- and Non-Pimp-Controlled Women

Abstract: A study of 50 incarcerated urban prostitutes finds that 40% have been under the control of a pimp. Pimp-controlled prostitutes are more likely to be single, to have failed to complete high school, to be non-White, to have never held a legitimate job, and to come from exceptionally dysfunctional families. Pimp-controlled prostitutes were younger when they had their first sexual experience, first used illegal drugs, and first engaged in prostitution. Pimp-controlled prostitutes are also more likely to be the victims of violence from customers, suggesting that the pressure to make extra money to support the pimp exposes these women to additional risk. Because of these accumulated adverse experiences, this group may require additional, long-term interventions.

Recent studies on in vivo fertilisation of in vitro matured horse oocytes

Abstract: Summary Fresh horse oocytes dissected from slaughterhouse ovaries were allocated to two groups depending on the degree of development of the cumulus investment. In Group I, the cumulus was fully compact whereas in Group II it was partially expanded. Basic culture medium (M199) was supplemented either with 20 per cent late oestrus mare serum (M199a) or 10 per cent foetal calf serum plus gonadotrophins (M199b). At the start of the culture, 70 per cent of Group I and 28 per cent of Group II oocytes were at germinal vesicle, or germinal vesicle breakdown stages. During culture in M 199a, the proportion of oocytes reaching metaphase of second meiosis (M II) was at a maximum after 30 h in culture for Group I oocytes (61 per cent) and after 24 h in culture for Group II oocytes (68 per cent). After culture in M199b, a higher proportion of Group I oocytes (89 per cent) displayed full expansion and mucification of the cumulus than when cultured in M199a (13 per cent), although the same proportion reached M II in each medium (63 per cent and 64 per cent respectively). Fluorographs of 1-dimensional gels of oocyte protein showed an accumulation of a polypeptide (MW 34 kDa) during culture. A total of 29 in vitro matured oocytes were transferred to the oviducts of four recently mated recipient mares judged to be at the point of ovulation. Uterine flushing of these mares eight days after surgery resulted in the recovery of seven blastocysts, two of which were then transferred surgically to the uteri of synchronised recipient mares and one pregnancy resulted.

A trial of three harness attachment methods and their suitability for long-term use on Lesser Black-backed Gulls and Great Skuas

Abstract: Tracking devices are useful in studying the movement and behaviour of birds throughout the year. However, the effects of device attachment must be monitored for bird welfare and the scientific veracity of information gathered. We report on a trial of three different harness types (leg-loop, body and wing) for attaching GPS devices to Lesser Black-backed Gulls Larus fuscus and of a leg-loop harness on Great Skuas Stercorarius skua. This trial evaluated the functionality of the device whilst deployed, harness retention and the effects of each harness on the birds. The leg-loop harness prevented the devices from charging, due to feathers overlapping their solar panels, and individuals of both species shed this attachment during the first breeding season. For Lesser Black-backed Gull, devices functioned properly when attached using body and wing harnesses; foraging behaviour and territory attendance of birds were similar to the findings of other studies. Despite small sample sizes, annual adult survival rates...