Institution
University of A Coruña
Education•A Coruña, Spain•
About: University of A Coruña is a education organization based out in A Coruña, Spain. It is known for research contribution in the topics: Population & Artificial neural network. The organization has 4661 authors who have published 9399 publications receiving 171951 citations. The organization is also known as: University of La Coruna & University of La Coruña.
Topics: Population, Artificial neural network, Context (language use), Computer science, Feature selection
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that occupational exposure to PB may influence the immune system by impairing several mechanisms, which might ultimately produce deregulation of the immune response and diminish immunosurveillance in exposed individuals.
Abstract: Although adverse health effects produced by lead (Pb) have long been recognized, studies regarding the immunotoxic effects of occupational exposure report conflicting results. In a previous study, alterations in some immunological parameters were noted in 70 Pb-exposed workers. In view of these results, it was of interest to extend this study comprising a larger population and increasing the number of immunological endpoints assessed. Accordingly, in this study the immunotoxic effects of occupational exposure to Pb were assessed by analyzing (1) percentages of lymphocyte subsets (CD3+, CD4+, CD8+, CD19+, and CD56+/16+); (2) concentration of plasma cytokines, namely, interleukin (IL) 2, IL4, IL6, IL10, tumor necrosis factor (TNF) α, and interferon (IFN) γ; and (3) plasma concentrations of neopterin, tryptophan (Trp), and kynurenine (Kyn). In addition, the possible influence of genetic polymorphisms in the vitamin D receptor (VDR) and δ-aminolevulinic acid dehydratase (ALAD) genes on immunotoxicity paramete...
71 citations
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TL;DR: Application of rTMS over the DLPFC as a 10 day course had no significant effect on motor functions and clinical motor status, and the improvement in performance of motor tasks can be attributed to the effects of practice.
71 citations
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American Board of Surgery1, United Arab Emirates University2, Queen Elizabeth Hospital Birmingham3, University of Washington4, University of Cambridge5, Tan Tock Seng Hospital6, Harvard University7, Mayo Clinic8, University of Michigan9, Wayne State University10, University of Zagreb11, Hebrew University of Jerusalem12, Rambam Health Care Campus13, University of Colorado Denver14, VA Boston Healthcare System15, University of Santiago de Compostela16, University of Alberta17, Northeast Ohio Medical University18, Transilvania University of Brașov19, University of California, San Diego20, Tianjin Medical University21, Jagiellonian University Medical College22, Tbilisi State Medical University23, Qatar Airways24, Ovidius University25, Virginia Commonwealth University26, Stanford University27, State University of Campinas28, Geneva College29, University of A Coruña30, Mansoura University31, Universidade Federal de Juiz de Fora32, Pinnacle Financial Partners33, Ruhr University Bochum34, Inje University35, Erzincan University36, Universiti Sains Malaysia37, St. Louis College of Pharmacy38, Australian National University39, University of Belgrade40, Yeshiva University41, National Cheng Kung University42, Yonsei University43, University of Helsinki44, Mahidol University45, University of Health Sciences Antigua46, Washington University in St. Louis47, Hacettepe University48, University of Florida49, Karolinska University Hospital50, University of Valle51, University of Coimbra52, Imperial College London53, Medical University Plovdiv54, Catholic University of the Sacred Heart55, Istituto Superiore di Sanità56, Pennsylvania State University57, University of Rennes58, Radboud University Nijmegen59
TL;DR: In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide as mentioned in this paper.
Abstract: In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.
71 citations
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TL;DR: In this article, a comparative study of these properties has been undertaken in virgin, mechanical recycled and commercial recycled PET samples, and the presence-absence of linear and cyclic oligomeric species was measured by mass spectrometry techniques, as MALDI-TOF.
71 citations
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TL;DR: It is shown how the suppression of AtPrx52 causes a change in lignin composition, mainly at the level of stem interfascicular fibers, at late stages of the lignification process.
Abstract: Lignins result from the oxidative polymerization of three hydroxycinnamyl (p-coumaryl, coniferyl and sinapyl) alcohols in a reaction mediated by peroxidases (EC 1.11.1.7) and laccases (EC 1.10.3.2), yielding H, G and S units, respectively. Although both acidic and basic peroxidases can oxidize p-coumaryl and coniferyl alcohol, only basic peroxidases are able to oxidize sinapyl alcohol. The AtPrx52 from Arabidopsis is a basic peroxidase that has been reported to be highly homologous to the basic peroxidase of Zinnia elegans, the only peroxidase which has been unequivocally linked to lignin formation. Here, we show how the suppression of AtPrx52 causes a change in lignin composition, mainly at the level of stem interfascicular fibers. Quantification of lignins in two different atprx52 knock-out mutants revealed a decrease of lignin amount compared with wild type. The S/G ratio, obtained by both nitrobenzene oxidation and thioacidolysis, indicated a decrease in S units in the atprx52 mutants. As deduced from Wiesner and mainly Maule staining, this reduction in S unit content appears to be restricted to the interfascicular fibers. Moreover, quantitative polymerase chain reaction analysis in atprx52 plants showed a general downregulation of genes involved in lignin biosynthetic pathway, as well as genes related to secondary cell wall. On the other hand, other routes from phenylpropanoid metabolism were induced. Taken together, our results indicate that AtPrx52 is involved in the synthesis of S units in interfascicular fibers at late stages of the lignification process.
71 citations
Authors
Showing all 4765 results
Name | H-index | Papers | Citations |
---|---|---|---|
Francisco J. Blanco | 84 | 789 | 33319 |
Gonzalo Navarro | 76 | 615 | 23062 |
James R. Davie | 63 | 204 | 17091 |
David Posada | 62 | 197 | 80926 |
Mikael Kubista | 58 | 218 | 24551 |
Germán Bou | 58 | 308 | 17715 |
Ruben Juanes | 49 | 249 | 9188 |
Alberto Arce | 46 | 162 | 6133 |
José Benito Quintana | 46 | 132 | 7528 |
Christian Kennes | 46 | 183 | 6399 |
María C. Veiga | 45 | 170 | 6004 |
Daniel Lopez | 44 | 221 | 7452 |
Roberto J. J. Williams | 44 | 212 | 7536 |
Rosario Rodil | 43 | 126 | 5896 |
Hector Gomez | 43 | 228 | 6747 |