University of Western Ontario

About: University of Western Ontario is a education organization based out in London, Ontario, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 46971 authors who have published 99859 publications receiving 3741703 citations. The organization is also known as: UWO & University of Western Ontario.

Configuring role-based access control to enforce mandatory and discretionary access control policies

Abstract: Access control models have traditionally included mandatory access control (or lattice-based access control) and discretionary access control. Subsequently, role-based access control has been introduced, along with claims that its mechanisms are general enough to simulate the traditional methods. In this paper we provide systematic constructions for various common forms of both of the traditional access control paradigms using the role-based access control (RBAC) models of Sandhu et al., commonly called RBAC96. We see that all of the features of the RBAC96 model are required, and that although for the manatory access control simulation, only one administrative role needs to be assumed, for the discretionary access control simulations, a complex set of administrative roles is required.

What Does the Narcissistic Personality Inventory Really Measure

Abstract: The Narcissistic Personality Inventory (NPI) is a widely used measure of narcissism. However, debates persist about its exact factor structure with researchers proposing solutions ranging from two to seven factors. The present research aimed to clarify the factor structure of the NPI and further illuminate its nomological network. Four studies provided support for a three-factor model consisting of the dimensions of Leadership/Authority, Grandiose Exhibitionism, and Entitlement/Exploitativeness. The Leadership/Authority dimension was generally linked to adaptive outcomes whereas the other two dimensions, particularly Entitlement/Exploitativeness, were generally linked to maladaptive outcomes. These results suggest that researchers interested in the psychological and behavioral outcomes associated with the NPI should examine correlates at the facet level. In light of the findings, we propose a hierarchical model for the structure of the NPI and provide researchers with a scoring scheme for this commonly used instrument.

Potential Therapeutic Targets for Cardiac Fibrosis TGFβ, Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

Abstract: Fibrosis is one of the largest groups of diseases for which there is no therapy but is believed to occur because of a persistent tissue repair program. During connective tissue repair, "activated" fibroblasts migrate into the wound area, where they synthesize and remodel newly created extracellular matrix. The specialized type of fibroblast responsible for this action is the alpha-smooth muscle actin (alpha-SMA)-expressing myofibroblast. Abnormal persistence of the myofibroblast is a hallmark of fibrotic diseases. Proteins such as transforming growth factor (TGF)beta, endothelin-1, angiotensin II (Ang II), connective tissue growth factor (CCN2/CTGF), and platelet-derived growth factor (PDGF) appear to act in a network that contributes to myofibroblast differentiation and persistence. Drugs targeting these proteins are currently under consideration as antifibrotic treatments. This review summarizes recent observations concerning the contribution of TGFbeta, endothelin-1, Ang II, CCN2, and PDGF and to fibroblast activation in tissue repair and fibrosis and the potential utility of agents blocking these proteins in affecting the outcome of cardiac fibrosis.

Simultaneous Wireless Information and Power Transfer (SWIPT): Recent Advances and Future Challenges

Abstract: Initial efforts on wireless power transfer (WPT) have concentrated toward long-distance transmission and high power applications. Nonetheless, the lower achievable transmission efficiency and potential health concerns arising due to high power applications, have caused limitations in their further developments. Due to tremendous energy consumption growth with ever-increasing connected devices, alternative wireless information and power transfer techniques have been important not only for theoretical research but also for the operational costs saving and for the sustainable growth of wireless communications. In this regard, radio frequency energy harvesting (RF-EH) for a wireless communications system presents a new paradigm that allows wireless nodes to recharge their batteries from the RF signals instead of fixed power grids and the traditional energy sources. In this approach, the RF energy is harvested from ambient electromagnetic sources or from the sources that directionally transmit RF energy for EH purposes. Notable research activities and major advances have occurred over the last decade in this direction. Thus, this paper provides a comprehensive survey of the state-of-art techniques, based on advances and open issues presented by simultaneous wireless information and power transfer (SWIPT) and WPT assisted technologies. More specifically, in contrast to the existing works, this paper identifies and provides a detailed description of various potential emerging technologies for the fifth generation communications with SWIPT/WPT. Moreover, we provide some interesting research challenges and recommendations with the objective of stimulating future research in this emerging domain.