Showing papers in "Acta Tropica in 2015"

TL;DR: Control efforts are generally fragmented and uncoordinated and additional control measures including health education, domestic livestock animal treatment/vaccination and dog vaccination are needed in CE-endemic areas to accelerate progress.

TL;DR: The evidence shows that dogs, cats, commensal rodents and domesticated guinea pigs are able to maintain T. cruzi in the absence of any other host species, and various study cases of how eco-epidemiological and genetic-marker evidence helped to unravel transmission cycles and identify the implicated hosts are provided.

TL;DR: In this paper, the evolution of insecticide resistance in triatomines is reviewed and the main resistance mechanisms (i.e. enhanced metabolism, altered site of action and reduced penetration) were described in the T. infestans resistant to pyrethrods.

TL;DR: A new strategy for controlling the liver fluke infection using the EcoHealth/One Health approach was introduced into the Lawa Lake area in Khon Kaen province, Thailand, and the infection rate in the more than 10 villages surrounding the lake has declined to approximate one third of the average as estimated by a baseline survey.

TL;DR: It is demonstrated that in addition to value as molecular markers for DTU assignment, Cytb, ITS rDNA and the spliced leader (SL) polymorphic sequences suggest spatially structured populations of Tcbat, and Phylogenetic and phylogeographical analyses, multiple molecular markers specific to Tcbats strongly support the definitive classification of T cbat as a new DTU.

TL;DR: The results demonstrate the complexity of the Trypanosoma cruzi reservoir system and its transmission strategies, indicating that there is considerably more to be learned regarding ecology of T. cruzi.

TL;DR: The aim of this paper is to discuss the main ecological interactions between the parasite Trypanosoma cruzi and its hosts, the mother and the fetus, leading to the transmission and development of congenital Chagas disease.

TL;DR: This study provides new insights into larval invasion, host-Trichinella interaction and for screening vaccine candidate antigens and Gene ontology analysis revealed that proteins involved in generation of precursor metabolites and energy were enriched in IIL at level 4.

TL;DR: Unless effective means to reduce contact between people and palm-living triatomines are devised, palms will contribute to maintaining long-term and widespread, albeit possibly low-intensity, transmission of human Chagas disease.

TL;DR: The potential for vulnerability maps to inform cholera surveillance, early warning systems, and disease prevention and control is highlighted, with a predicted increase in areas with environmental conditions suitable for V. cholerae distribution under current and future climate scenarios.

TL;DR: In this article, the authors proposed a risk-mapping-based approach for detection of transmission hotspots by means of geospatial and other dynamic approaches, which facilitates decision-making at the technical as well as the political level.

TL;DR: The significantly higher prevalence of active schistosome infections as shown by the urine and serum UCP-LF CAA assays has implications for the national control and elimination programme in P.R. China, particularly in respect to case-finding and intervention strategies.

TL;DR: A new taxonomic checklist is provided, annotated with respective vector competencies for transmission of arboviral vector incrimination studies, and revealed the widespread presence of the highly efficient West Nile virus vector Cx.

TL;DR: The presence of a particular allele significantly associated with urticaria patients was detected, and the clinical implications of these findings are herein discussed.

TL;DR: Gaps in current knowledge of disease burden are identified, and interim approaches to disease burden assessment are discussed, and Gap-adjusted Life Year and Quality-Adjusted Life Year metrics are discussed.

TL;DR: The rTs31 protein of T. spiralis could be considered as a potential diagnostic antigen for trichinellosis.

TL;DR: IL10 and CXCL10/IP10 play a role in the disease severity associated with induction of vascular leakage and a novel association with changes in liver dysfunction and this is the first study demonstrating cytokine and chemokine association with severity during dengue fever in Brazilian children.

TL;DR: Biotic and abiotic factors help to explain the recent increase of oral transmission outbreaks of Chagas disease, distributed in nine eco-regions of America.

TL;DR: Because the two antimalarial drugs quinine and artemisinin were discovered through improved understanding of the indigenous knowledge of plants, bioprospecting Sub-Saharan Africa's enormous plant biodiversity may be a source of new and better drugs to treat malaria.

TL;DR: Investigation of the influence of larval habitats and seasonal factors on the diversity and abundance of Culicidae fauna in Anhanguera Park, one of the largest remaining green areas in the city of São Paulo finds significant relationships were observed between abundance and seasonality.

TL;DR: A growing number of field studies indicate that natural hybridization in T. cruzi may be frequent, non-obligatory and idiosyncratic; potentially involving independent exchange of kinetoplast and nuclear genetic material as well as canonical meiotic mechanisms as mentioned in this paper.

TL;DR: The vaccination of mice with rTsGST induced the Th1/Th2-mixed type of immune response with Th2 predominant (high levels of IgG1) and partial protective immunity against T. spiralis infection.

TL;DR: Two main clades of T. cruzi, lineages I and II, were found to be sympatric (all habitats and seasons) in the Zoh-Laguna landscape, suggesting that no species-specific interactions occur between the parasite and any mammal host, in any habitat.

TL;DR: A strong surveillance program must be implemented to evaluate and monitor the distribution and the true importance of non-dengue arboviruses in the etiology of acute febrile illnesses, as molecular and evolutionary analyses indicate that two MAYV genotypes are co-circulating in Mato Grosso, Brazil.

TL;DR: The cost information contained herein can be used to inform rational decision making in control and elimination programs, and to assess potential synergies with existing vector-borne disease control programs, but programs would benefit significantly from new cost data collection.

TL;DR: A loop-mediated isothermal amplification (LAMP) assay targeting 28S rDNA is applied for the rapid and effective detection of Schistosoma japonicum DNA in infected and prepatent infected O. hupensis snails, which will form a guide for surveillance and response strategies in high risk areas.

TL;DR: Besides its success in separating known species, it is found that DNA barcoding is useful in revealing population differentiation and cryptic diversity, and thus promises to be a valuable tool for epidemiological studies of leishmaniasis.

TL;DR: Real-time PCR is an effective tool for diagnosing strongyloidiasis and could be applied in association with parasitological methods in epidemiological studies in endemic areas and in immunocompromised populations who are at risk of fatal disease.

TL;DR: A follow-up study is recommended to validate the model on a larger scale in the Mekong Delta region and to analyze the possibility of incorporating a climate-based d Dengue early warning method into the national dengue surveillance system.

TL;DR: Analysis of three stool samples with KK plus a single FECT was considered as diagnostic 'gold' standard and resulted in prevalence estimates of hookworm, Opisthorchis viverrini, Ascaris lumbricoides, Trichuris trichiura and Schistosoma mekongi, which produced similar results than those obtained by a mathematical model for most helminth infections.