Showing papers in "Bioactive Materials in 2019"

TL;DR: A comprehensive summary of recent trends in development of single- (metal, ceramics and polymers), composite-type and cell-laden scaffolds that in addition to mechanical support, promote simultaneous tissue growth, and deliver different molecules or cells with therapeutic or facilitating regeneration effect is offered.

TL;DR: This review explores open-cellular structural design for porous metal implant applications, in relation to the mechanical properties, biocompatibility, and biodegradability, of metal implants with an enhanced biomorphic environment.

TL;DR: It is hoped that synthetic polymer-ceramic composites such as PLLA/HA and PCL/HA will provide advantages such as eliminating the stress shielding effect and the consequent need for revision surgery.

TL;DR: This review provides a brief summary of state-of-art of surface biofunctionalization on implantable metals by CaP coatings and gives insight into the representative biofunctions, i.e. osteointegration, corrosion resistance and biodegradation control, and antibacterial property, provided by CaPs coatings for metallic implant materials.

TL;DR: This review outlines designs of self-assembly peptide (β-sheet, α-helix, collagen-like peptides, elastin-like polypeptides, and peptide amphiphiles) with potential additional functionalities and their biomedical applications in bioprinting, tissue engineering, and drug delivery.

TL;DR: Zn-MBGNs show great potential as bioactive fillers or drug delivery systems in a variety of applications including bone regeneration and wound healing and are seen to improve the differentiation of osteoblast-like cells (MG-63).

TL;DR: The present review provides a detailed overview of the benefits and issues of metal alloys when used as biomedical implants and how they are improved by bioactive glass-based coatings for biomedical applications.

TL;DR: Besides the high effective antibacterial efficacy provided by photothermal therapy (PTT) and photodynamic therapy (PDT), the RGDC decorated surface can also possess an excellent performance in osteogenesis in vivo.

TL;DR: This article introduced four research approaches about the new tendency of applying new materials and technologies to cooperate with traditional chemicals to achieve better and longer effects with lower environment pollution through synergistic actions.

TL;DR: In this article, the authors highlight the status of the most advanced and widely explored interaction of nanoparticle-based platforms and calcium phosphate compounds with an eye toward translating the potential of these approaches to the dental clinical reality.

TL;DR: Corrosion product formed on zinc sample during 2 weeks immersion in saline solution has been investigated and probable mechanisms of zinc corrosion products formation are presented.

TL;DR: The basic properties of embryonic stem cells, induced pluripotent stem cells (iPSCs) and adult stem cells are summarized and the combination of stem cells and biomaterials for tissue repair applications was reviewed in terms of nervous, cardiovascular, pancreatic, hematopoietic and musculoskeletal system.

TL;DR: It is demonstrated that the 3D printing of silk fibroin-based hybrid scaffolds, in combination with PRP post-treatment, might be a more efficient strategy to promote osteogenic differentiation of adult stem cells and has significant potential to be used for bone tissue engineering.

TL;DR: The profuse twinning in the as-cast Zn-Mg alloys accelerated crack growth in tension due to twinning impingement which caused local stress concentrations and initiates cracking.

TL;DR: Light is shed on the direction of surface topography design for future medical implants to combat against antibiotic-resistant implant-associated infections without using antibiotics by integrating the persistent topographical antibacterial activity and the non-invasive X-ray induced photocatalytic antibacterial property of TiO2.

TL;DR: Ag-containing coatings demonstrated strong antibacterial effect against Staphylococcus aureus AТСС 6538-P and MTT in vitro test with 3T3-L1 fibroblasts showed no cytotoxicity appearance on Sr-Si-incorporated coatings.

TL;DR: The results demonstrate the incorporation of a hierarchical macro-micro-nano roughness on titanium produces a stellate morphology typical of mature osteoblasts/osteocytes, rapid and random migration, and improved osteogenic differentiation in seeded MSCs.

TL;DR: Results showed that the PD-based coating method facilitated aligned and uniform cell growth, therefore holds great promise for cell sheet engineering as well as completely biological tissue biomanufacturing.

TL;DR: Recent bioengineering strategies involving biodegradable composite scaffolds, bioactive factors, and external stimuli alone or in combination to support peripheral nerve regeneration are summarized.

TL;DR: The results suggest that the NT/GMs/SF dressings may work as an effective support for control release NT to promote DFU wound healing.

TL;DR: Gelatin-coated, 3D sponge-like scaffolds based on 45S5 bioactive glass were produced using the foam replication technique as mentioned in this paper, which showed significant strengthening and toughening effects of the gelatin coating with compressive strength values in the range of cortical bone.

TL;DR: It is shown that ANAB processing of PEEK surface enhances the bioactivity of implantable medical devices without an additive or a coating.

TL;DR: In vivo implantation showed that the newly designed Mg–Zn–Ca clip can successfully ligated carotid artery and no blood leakage occurred post-surgery, and it was found that Mg-Zn-Ca alloy exhibited non-cytotoxic to L929 cells.

TL;DR: The effects of testing solutions and conditions on hydroxyapatite (HAp) formation as a means of in vitro bioactivity evaluation of B2O3 containing 45S5 bioactive glasses were systematically investigated and it was found that addition of boron oxide delayed the HAp formation in both SBF and K2HPO4 solutions.

TL;DR: This review presents the representative Mg implants of three categories, orthopedic implants, surgical implants, and intervention implants and provides an overview of current achievement in China from academic publications and Chinese patents to provide a systematic way to translate Mg and its alloy implants from experiment designs to clinical products.

TL;DR: In this work, Ti—Mg metal-metal composites (MMCs) were successfully fabricated by spark plasma sintering (SPS) and in vitro, the proliferation and differentiation of SaOS-2 cells in response to Ti-Mg MMCs were investigated.

TL;DR: Most studies included in the present systematic review have been conducted in-vitro or in-Vivo, with few randomized controlled clinical trials (RCTs).

TL;DR: In this review, the effects of topographic cues on the behaviors of corneal cells, including cell morphology, adhesion, migration, and proliferation are summarized.

TL;DR: Electrochemical methods including Open Circuit Potential (OCP) and Electrochemical Impedance Spectroscopy (EIS) were used and demonstrated a decreasing of the substrate degradation rate when PDOPA was used as interlayer supposing a synergistic effect when it was used together with the organic coating.

TL;DR: Original hydrogel biopolymer scaffolds based on a blood plasma cryoprecipitate and collagen and formed under conditions of enzymatic hydrolysis have good prospects as cell carriers and can be widely used in regenerative medicine.