Showing papers in "Biochemical and Biophysical Research Communications in 1963"

TL;DR: The occurrence of a TPNH-induced peroxidation of lipids in rat-liver microsomes is reported and the reaction requires activation by ADP or other pyrophosphates, and appears to be coupled to the TPNh oxidase system of the microsome.

TL;DR: The finding of two cyclic nucleotides in the urine of Fisher rats indicates the existence of only a certain type of intact nucleotide in urine represents a selective biological behavior that may prove of interest in relation to rather general biochemical and biophysical characteristics of a system.

TL;DR: It is shown that alloxan-diabetes in the rat and fatty acid perfusion of the rat heart lead to an increase in tissue citrate, and that this substance is a direct inhibitor of PFK.

TL;DR: The contributory factor of capture and stabilization of the electronic charge-by the additive molecule to radiosensitization is discussed and the effect of N-ethylmaleimide, pbenzoquinone, benzophenone, and diacetyl on Serratia marcescens is discussed.

TL;DR: Palmityl-CoA has been shown to inhibit CS from pig heart and from rat liver non-competitively with respect to acetyl CoA as mentioned in this paper, and the mechanism of the inhibition and its physiological significance as a possible regulatory factor in hepatic ketogenesis is discussed.

TL;DR: The level of acetyl-CoA in the livers of alloxan diabetic rats rendered ketotic by withdrawal of insulin and administration of adrenal corticoid hormones and of rats madeketotic by fat feeding is 2.5 – 3 times higher than in untreated controls, which is taken as evidence in support of the theory that ketosis occurs as a result of over-production of acetylene in the liver.

TL;DR: Evidence is presented for the presence of allotypic specificities of both groups in rabbit 19S protein, as well as in 7S γ-globulin.

TL;DR: The experiments described here on the effectiveness of partially purified L-asparaginase of GPS in inhibiting tumor growth support Broome's proposal that the activity of GPS is responsible for the anti-lymphoma effect.

TL;DR: Direct evidence is described for an energy-dependent pyridine nucleotide transhydrogenase reaction, involving a reduction of TPN by DPNH, catalyzed by submitochondrial preparations from both rat liver and beef heart.

TL;DR: This communication describes attempts to elucidate the nature of the inhibitor and the mechanism of inhibition of acetyl CoA carboxylase.

TL;DR: In this paper, the authors present evidence for the occurrence of a 2-keto-3-deoxy-onic acid (Compound I) as a glycosidically bound constituent in preparations of cell wall lipopolysaccharide (LPS) obtained from Escherichia coli 0111-B4 and from a mutant of this organism, E. coli J-5 ( Heath and Elbein, 1962 ).

TL;DR: The crystallization of 2-oxoglutarate L-aspartate transaminases of mitochondrial and extramitochondrial origin are described, respectively, and some of their properties are described.