Showing papers in "Diabetes Research and Clinical Practice in 2016"

TL;DR: Diabetes imposes a large economic burden on health care systems across the world, yet varies across world regions, and prevention and effective management of diabetes should be a public health priority to reduce the financial burden.

TL;DR: In this pilot trial, 2days of IER compared with CER resulted in similar improvements in glycaemic control and weight reduction offering a suitable alternative treatment strategy.

TL;DR: Compared to conventional care, telemedicine is more effective in improving treatment outcomes for diabetes patients, especially for those with type 2 diabetes.

TL;DR: The negative impact of diabetes on joints could be explain by the induction of oxidative stress and pro-inflammatory cytokines but also by advanced age products accumulation in joint tissues exposed to chronic high glucose concentration.

TL;DR: Double diabetes seems to be an independent and important risk factor for persons with T1DM in developing macrovascular and microvascular comorbidities and patients should be identified and development of MS should be avoided.

TL;DR: Findings on HbA1c, anti-inflammatory and anti-oxidative effects of probiotics in the clinical setting, however, remain inconsistent, implying the need for well-designed clinical studies to further assess the potential beneficial effects of Probiotic interventions in management of T2DM.

TL;DR: In this paper, the association of daily and day-to-day glucose variability with oxidative stress was found in patients with Type 2 diabetes mellitus. But, these correlations remained significant after adjustment for clinical factors (sex, age, duration of diabetes, smoking habit, insulin use, statin use, angiotensin II receptor blocker use, BMI, LDL-C, HDLC, TG, eGFR, and systolic blood pressure).

TL;DR: Insight is provided into the detection of groups at high risk of hypoglycemia-associated dementia, and specific strategies to minimize the potential burdens associated with hypoglyCEmia-related neurocognitive disorders in patients with T2DM are proposed.

TL;DR: To the authors' knowledge this is the first trial to show an improvement in glucose handling using HOMA parameters in participants with prediabetes, and a larger randomized controlled trial is warranted to confirm these findings.

TL;DR: Metformin-SU treatment was associated with an increased risk of subsequent severe hypoglycemia, cardiovascular events, and all-cause mortality compared with metformin+DPP4i, and glibenclamide had the highest risks.

TL;DR: Diabetes patients using the Welltang application achieved statistically significant improvements in HbA1c, blood glucose, satisfaction of patients to use of WellTang, diabetes knowledge, and self-care behaviors.

TL;DR: Lifetime depression and anxiety increase risk of more severe psychological symptoms, hyperglycaemia, and difficulties with health behaviour in type 2 diabetes.

TL;DR: Yoga was the most effective in lowering glycated haemoglobin A1c (HbA1c) levels and a higher frequency of regular leisure-time physical activities was found to be more effective in reducing HbA 1c levels.

TL;DR: This nation-wide real-world data analysis on medication-prescribed diabetes demonstrates that the current prevalence in Greece is 7.0%, with wide age variation and high figures in older adults.

TL;DR: In the Russian adult population, 19.3% had pre-diabetes, T2DM prevalence was 5.4%, and 54% of subjects with diabetes were previously undiagnosed, which may help to develop a new type 2 diabetes mellitus predictive, preventative and management programme in Russia.

TL;DR: Most Brazilian T1D patients did not adhere to their prescribed insulin therapeutic regimen, according to the MMAS 4-item scale, and this tool should be initially used to identify non-adherent patients and help them overcome the barriers to adherence to their prescriptions.

TL;DR: Compared to the general population, adults with type 1 diabetes experienced lower health-related quality of life, were more frequently unemployed, had more sick leave per year and were slightly better educated.

TL;DR: An HbA1c of 6.5-6.9% is associated with the lowest risk of fracture in elderly patients with diabetes, which may be a marker of infrequent patient-provider interaction.

TL;DR: In patients with T1DM, DPP4 inhibitors combined with insulin do not increase or decrease the risk of hypoglycemia and do not decrease HbA1c levels.

TL;DR: The meta-analysis showed that there was no significant association between DPP-4 inhibitor use and the incidence of fractures, and a larger, up-to-date review of the subject was offered.

TL;DR: This is the first randomized, controlled trial demonstrating that CHWs can improve psychological symptoms and self-reported health among Latinos with type 2 diabetes.

TL;DR: A clear deterioration of lean mass and muscle functions among adult DM2 patients of up to 60years old is found, independent of length of disease, metabolic control, vitamin D status and presence of microvascular complications and pain.

TL;DR: A high proportion of individuals with diabetes are not on diabetes treatment and of those on treatment a high proportion have high glycaemic concentrations, similar to that seen in high-income populations.

TL;DR: This meta-analysis suggests either no association or a modest positive one between DM and VTE in the general population and DM is unlikely to play a major role in VTE development.

TL;DR: Ascertainment of events from clinical notes more than doubled the completeness of hypoglycemia capture overall relative to measures from structured data, and increased capture of non-serious events more than 20-fold.

TL;DR: A large proportion of patients on insulin-based therapy fail to reach glycemic goals, and more education of clinicians may improve insulin intensification rates and increase the proportion of Patients reaching glycemic targets.

TL;DR: The risk for diabetes associated with a 1-h level >8.6mmol/l (155mg/dl) is increased and further worsened in the presence of IGT, and identifying individuals at risk with a1-h-PG glucose level during an OGTT is recommended.

TL;DR: Hypoglycemia is significantly associated with the risk of dementia in Korean type 2 DM patients aged ⩾60years, and there was a significant linear trend toward an increased dementia risk commensurate with an increasing number of hypoglycemic events.

TL;DR: It is shown that helminth infections can be associated with improved metabolic outcomes, and understanding of the mechanisms underlying this relationship could facilitate the development of novel strategies to prevent or delay T2DM.

TL;DR: Adherence to SMBG was sub-optimal, especially among those who had to pay for glucostrips, and patient education and provision of free glucOSTrips are recommended to improve adherence and glycemic control.