scispace - formally typeset
Search or ask a question

Showing papers in "Gynecologic Oncology in 1980"


Journal ArticleDOI
TL;DR: It is still not clear how many patients can be salvaged by treatment to extended paraaortic radiation fields, but longer periods of follow-up in patients whose treatment plans were based on surgical staging information will be required.

296 citations


Journal ArticleDOI
TL;DR: For appropriately selected patients, separate groin incisions for inguinal lymphadenectomy appear to result in lower morbidity than traditional methods, without compromising survival.

227 citations



Journal ArticleDOI
TL;DR: Methylprednisolone was given to patients receiving cancer chemotherapy and of 11 patients with prior chemotherapy and emesis, 8 obtained noticeable relief, although 1 had marked nausea which did not recur when treated with the steroid.

153 citations


Journal ArticleDOI
TL;DR: A total of 424 patients with squamous cell carcinoma of the vulva have been followed 3–21 years, and the FIGO system seemed to be the most useful in predicting prognosis.

101 citations


Journal ArticleDOI
TL;DR: In this article, a retrospective evaluation of 52 patients with positive lymph nodes at the time of curative primary surgery for invasive squamous carcinoma of the vulva reveals that those patients with three or less unilaterally positive groin nodes have an excellent prognosis.

89 citations


Journal ArticleDOI
TL;DR: The pretreatment evaluation of younger patients, especially those with Stage II-B cancer, should be more aggressive at attempts to detect cancer beyond the usual treatment fields, because of the poorer prognosis for patients under age 35.

88 citations


Journal ArticleDOI
TL;DR: The relatively frequent occurrence of "adenoma malignum" of the cervix, an otherwise rare form of cervical cancer, in women with the Peutz-Jeghers syndrome warrants close supervision of these patients by a gynecologist to assure early detection and treatment of this highly malignant tumor.

70 citations


Journal ArticleDOI
TL;DR: It is felt that consideration should be given to the use of radical vulvectomy with pelvic exenteration in patients with advanced, but resectable carcinoma of the vulva.

65 citations


Journal ArticleDOI
TL;DR: A safe and effective dosage level for radiation therapy has been established with the described limited surgical exploration and control of the cancer occurred in one patient with massive metastatic periaortic disease.

65 citations


Journal ArticleDOI
TL;DR: A case of oat cell carcinoma of the cervix whose diagnosis was established by light and electron microscopic studies was reported, and the patient was pregnant with a male fetus, and was given a course of cis -diamminedichloroplatinum before definitive surgical therapy.

Journal ArticleDOI
TL;DR: The nature of extrauterine involvement in surgical-pathologic Stage III adenocarcinoma of the endometrium is of major prognostic significance.

Journal ArticleDOI
TL;DR: A critical review of the treatment features of the 15 patients who developed vaginal fistulas in both series identified pelvic inflammatory disease, blunt dissection, and excessive vaginal apex doses as contributing factors.

Journal ArticleDOI
TL;DR: This case illustrates the confusion that can occur in making a proper pathologic diagnosis and the propensity for local recurrence and the sites of metastases in epithelioid sarcoma involving the vulva.

Journal ArticleDOI
TL;DR: Four of thirteen patients with advanced endometrial adenocarcinoma had an objective response to treatment with cis -dichlorodiammine platinum (II) by high-dose infusion after failing prior intensive combination chemotherapy.

Journal ArticleDOI
TL;DR: It is estimated that due to the improved survival, no increase in mortality from endometrial cancer will be produced unless estrogen users have an incidence rate more than 2.5 times that of nonusers.

Journal ArticleDOI
TL;DR: A correlation is found in that the advanced depth of cervical stromal invasion appears to increase the risk of nodal involvement and also the subsequent recurrence in patients with negative nodes.

Journal ArticleDOI
TL;DR: It is concluded that combined preoperative external beam and intracavity radiation with total abdominal hysterectomy and bilateral salpingo-oophorectomy is the preferred treatment for stage II endometrial carcinoma ecause of the excellent survival and low morbidity.

Journal ArticleDOI
TL;DR: The authors' patient responded well to combination chemotherapy after surgery and survived 26 months, and the potential benefit of combination chemotherapy following surgery awaits further evaluation.

Journal ArticleDOI
TL;DR: Clinical data are tend to confirm clinical data that intraperitoneal 32 P may be effective as adjunctive treatment in early stage ovarian carcinoma, but should not be used when the risk of retro peritoneal lymph node involvement is high or when residual intraPeritoneal macroscopic disease is present.

Journal ArticleDOI
TL;DR: It is suggested that cervical adenocarcinoma is epidemiologically more closely related to endometrial adeno-cervix than to squamous cell carcinoma of the cervix.

Journal ArticleDOI
TL;DR: In the course of 30 years’ experience, I have encountered eight cases of carcinoma metastatic to the cervix from remote sites without involving the body of the uterus and Table 1 shows the sites of the primary tumor.

Journal ArticleDOI
TL;DR: Estradiol cytosolic receptor levels were determined in tumor tissue of 73 patients with adenocarcinoma of the uterus and preoperative radiation appeared to interfere with the determination of the tumor's receptor status.

Journal ArticleDOI
TL;DR: Toxicity following actinomycin D delivered in divided doses over 5 days was compared to that following single-dose administration in 18 patients with nonmetastatic trophoblastic disease.

Journal ArticleDOI
TL;DR: The ultrastructural findings in osteosarcoma of the uterus parallel observations in ostea of bone, and suggest an origin from mesenchymal cells capable of fibroblastic, osteoblastic, and histiocytic differentiation.

Journal ArticleDOI
TL;DR: It is suggested that the PEG assay may be a useful marker in patients with ovarian cancer as it detected significantly higher levels of immune complexes in the serum of ovarian cancer patients with known tumor when compared with patients who were in remission.

Journal ArticleDOI
TL;DR: Questions regarding tumor differentiation, residual carcinoma in the surgical specimen, and the need for radical hysterectomy in Stage II endometrial carcinoma are discussed.

Journal ArticleDOI
TL;DR: A retrospective study was undertaken on patients with multiprimaries associated with vulva carcinoma, analyzing in particular 33 patients with double epidermoid primaries of the vulva and cervix, finding that the commonest second primary is located in the cervix.

Journal ArticleDOI
TL;DR: Droperidol was found to be more effective in relieving the vomiting induced by this chemotherapeutic agent than prochlorperazine in women receiving cis -diamminedichloroplatinum.