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Showing papers in "International Journal of Biological Macromolecules in 2012"


Journal ArticleDOI
TL;DR: Pectin structure, sources and extraction procedures have been discussed focussing on the properties of the polysaccharide that can be tuned to optimize the gels for a desired application and possess a fundamental role in application of pectin in the biomedical field.

426 citations


Journal ArticleDOI
TL;DR: In future this room temperature optical ammonia sensor can be used for clinical and medical diagnosis for detecting low ammonia level in biological fluids, such as plasma, sweat, saliva, cerebrospinal liquid or biological samples in general for various biomedical applications in human.

283 citations


Journal ArticleDOI
TL;DR: Light is shed on effects of ionic liquids chemistry on structure, stability, and activity of enzymes, which will be helpful for the researchers in various biocatalytic applications.

272 citations


Journal ArticleDOI
TL;DR: It was shown that partial hydrolysis of guar gum could be achieved by inexpensive and food grade cellulase (Aspergillus niger) having commercial importance and utilization as a functional soluble dietary fiber for food industry.

268 citations


Journal ArticleDOI
Mingxian Liu1, Yun Zhang1, Chongchao Wu1, Sheng Xiong1, Changren Zhou1 
TL;DR: In vitro fibroblasts response demonstrates that both chitosan and chitOSan/HNTs nanocomposite films are cytocompatibility even when the loading of HNTs is 10%.

261 citations


Journal ArticleDOI
TL;DR: Biological activities of peptides from marine organisms are presented, emphasizing their potential applications in foods as well as pharmaceutical areas.

258 citations


Journal ArticleDOI
TL;DR: Developed calcium alginate/gum Arabic beads containing glibenclamide could possibly be advantageous in terms of advanced patient compliance with reduced dosing interval and increase in drug encapsulation efficiency and decrease in drug release were found.

173 citations


Journal ArticleDOI
TL;DR: A novel nano-adsorbent, β-cyclodextrin-chitosan (CDC) modified Fe(3)O(4) nanoparticles (CDCM) is fabricated for removal of methyl blue from aqueous solution by grafting CDC onto the magnetite surface and the adsorption capacity was about 90% of the initial saturation adsorptive capacity after being used four times.

166 citations


Journal ArticleDOI
TL;DR: The results suggest that the porous starch has a more excellent adsorption capacity than the native starch, and may be expected to have wide potential applications in many fields.

163 citations


Journal ArticleDOI
TL;DR: Because SQChN has the highest aspect ratio, its 0.1% dispersion had the highest shear stress and viscosity at the same shear rate in the four chitin nano-samples, and showed gel-like behavior in the wholeShear rate range from 10(-3) to 10(3) s(-1).

158 citations


Journal ArticleDOI
TL;DR: Tannic acid exhibited the highest cross-linking ability on myofibrillar protein as evidenced by higher decrease in free amino groups with coincidentally lower band intensity of myosin heavy chain (MHC).

Journal ArticleDOI
TL;DR: It is suggested that chitosan/f-MWCNT scaffolds are promising biomaterials for bone tissue engineering.

Journal ArticleDOI
TL;DR: The maximum theoretical adsorption capacities of the CSTG resin for Hg(2+), Cu (2+) and Zn(2+) were found to be 98±2, 76±1 and 52±1 mg g(-1), respectively, while the negative values of Gibbs free energy of adsorptive indicated the spontaneity of the adsor adaptation of all metal ions on the novel resin.

Journal ArticleDOI
TL;DR: The developed CS/nHAp/nCu-Zn scaffolds have advantageous and potential applications over the CS- nHAp scaffolds for bone tissue engineering.

Journal ArticleDOI
TL;DR: Biocompatible, 200 nm sized tetracycline encapsulated O-carboxymethyl chitosan nanoparticles (Tet-O-CMC Nps) via ionic gelation is developed for its sustained delivery of Tet into cells proving it to be an efficient nanomedicine to treat intracellular S. aureus infections.

Journal ArticleDOI
TL;DR: The results suggest that the nano-insulin-loaded hydrogels are a promising non-invasive TDD system for diabetes chemotherapy.

Journal ArticleDOI
TL;DR: In the current work chitosan was extracted from shrimp shells and then used as antibacterial exhaust finishing agent for grafted bamboo rayon and showed antibacterial activity against both types of bacterias which was durable till 30 washes.

Journal ArticleDOI
TL;DR: RRPP may be responsible for the pharmacological effect of anti-fatigue of Radix Rehmanniae Preparata, the mechanism was related to the increase of the storage of hepatic glycogen and the decrease of the accumulation of SUN and BLA.

Journal ArticleDOI
TL;DR: Excellent interconnected porosity, controlled biodegradation and enhanced cell proliferation of the novel chitosan-CS/HAp and chitOSan-AP-HAp scaffolds suggests that these scaffolds are promising biomaterials for bone tissue engineering.

Journal ArticleDOI
TL;DR: The prospective results allow the particles to be employed as site-specific HP controlled release system by tuning the CHT/TPP molar ratio.

Journal ArticleDOI
TL;DR: An implantation experiment in mouse skulls revealed that the composite scaffold provides a strong positive effect on bone formation in vivo in mice and has been shown to be more effective for new bone generation than chitosan-alginate scaffold.

Journal ArticleDOI
TL;DR: The results showed that LEPC1 exhibited significantly antioxidant activity at a concentration-dependent manner, indicating that the water-extractable polysaccharide fraction was a potent antioxidant and could be developed to be new health medicine for fighting against various human diseases.

Journal ArticleDOI
TL;DR: Cultures conducted in media containing shrimp shell waste supplemented with 5% (w/v) glucose were found to remarkably promote demineralization efficiency, without affecting deproteinization rates.

Journal ArticleDOI
TL;DR: The cloxacillin release profile from liquid paraffin beads followed Korsmeyer-Peppas model over a period of 8h with anomalous (non-Fickian) diffusion mechanism for drug release.

Journal ArticleDOI
TL;DR: The optimized Tropicamide-loaded CMTKP nanoparticles formulation showed ex vivo corneal permeation of tropicamide across isolated goat cornea comparable to its aqueous solution, indicating their suitability as ocular delivery system.

Journal ArticleDOI
Hongji Zhu1, Kai Sheng1, Erfu Yan1, Jianjun Qiao1, Feng Lv 
TL;DR: The antibacterial activity of polysaccharide from SMS against E. coli was the strongest, while the weakest against S. lutea, and the MICs of PL2 were 12.5, 25 and 100 μg/mL, respectively.

Journal ArticleDOI
TL;DR: Nanoparticle immobilized BGAL demonstrated improved stability after favoring multipoint covalent attachment and retained more than 50% enzyme activity up to the eleventh cycle.

Journal ArticleDOI
TL;DR: The results of this study suggest that DS loaded IPN microspheres were suitable for oral controlled release application.

Journal ArticleDOI
TL;DR: Interestingly, SFL presented as a relatively transparent aqueous solution with 10-30 nm particle size, whereas the three SFC samples exhibited a turbid solution with 100-300 nm particlesize, whereas SF formic acid solutions showed a higher viscosity than SF aqueously solutions and exhibited almost Newtonian fluid behavior.

Journal ArticleDOI
TL;DR: Native skin collagen fibers were successfully dissolved in the ionic liquid, 1-butyl-3-methylimidazolium chloride ([BMIM]Cl), and regenerated in different precipitators and the structure of regenerated collagen was characterized by FTIR and XRD.