Showing papers in "Journal of Critical Care in 2011"

TL;DR: In a large cohort of scheduled extubated patients, one third of patients developed extubation failure, of whom half needed reintubation, associated with increased mortality due to the development of new complications after reintsubation.

TL;DR: Results show that neutrophil activation occurring during inflammation and sepsis could be detected by plasma MPO concentration, and these concentrations may be a marker of the neutrophils proliferation and severity of inflammation.

TL;DR: Albumin and CRP were associated with 28-day mortality in hospitalized patients with CAP, and these markers increased prognostic performance when combined with the PSI scale.

TL;DR: In this article, the performance of procalcitonin (PCT), interleukin-6 (IL-6), and C-reactive protein (CRP) as percentage of baseline (POB) in predicting hospital survival was evaluated.

TL;DR: Crisis communication strategies include "flying by voice," the need to combat "mitigating language," the uses of "graded assertiveness" and "5-step advocacy," and the potential role of Situation, Background, Assessment, and Recommendation communication.

TL;DR: Although administered at the time of a respiratory crisis without being discussed in advance, tracheostomy shows good acceptance and results in acceptable QoL, and patients with ALS have a high chance of long-term survival after trachostomy for ARF.

TL;DR: Hypoalbuminemia and hyperchloremia were associated with mortality and this result involving chloride is something new and should be tested in future studies.

TL;DR: The AKIN definition, independently associated with ICU mortality, may allow unifying diagnostic criteria to further evaluate this condition that impacts morbidity and mortality.

TL;DR: Estimation of volume status based on physical examination showed a poor interobserver agreement between the examiners, and there was no significant correlation between physical examination-based estimation ofVolume status and CVP or TPTD-derived GEDVI.

TL;DR: The results support the need to review the current definition of septic shock and suggest hyperlactatemia could represent an objective parameter worth to be explored as a potential diagnostic criterion for septicshock.

TL;DR: Implementing a DDI screening procedure results in significantly lower number of important DDI in the MICU and shortens LOS, according to the multiple linear regression and simple regression analysis.

TL;DR: The 3 models have comparable capabilities for benchmarking purposes after customization and the main advantage of APACHE IV is the large number of diagnoses that enable subgroup analysis.

TL;DR: Although serum concentrations did not differ in critically ill patients from controls, low adiponectin levels at admission to ICU have been identified as an independent predictor of survival.

TL;DR: The tele-ICU intervention was cost-effective in the sickest patients with Simplified Acute Physiology Score II 50 or less and decreased hospital mortality without increasing costs significantly, suggesting hospital administrators may conclude that a tele- ICU program aimed at the Sickest patients is cost- effective.

TL;DR: Hyperglycemia after TBI was associated with poor clinical outcomes, but the predictive value of blood lactate level requires further investigation.

TL;DR: Admission hyperlactatemia is common in a general ICU and is associated with increased mortality, irrespective of presence of hypotension, and in patients without hypotension too, ICU mortality was significantly increased.

TL;DR: Use of a polyurethane-cuffed endotracheal tube was associated with a significant decrease in the rate of ventilator-associated pneumonia in this study.

TL;DR: The results suggest that admission serum BDNF and NSE levels are associated with the occurrence of delirium in ICU patients.

TL;DR: Volume loading decreased PPV and SVV; and vasodilators increased both, consistent with their known cardiovascular effects, can be used to drive fluid resuscitation algorithms in the setting of changing vasoactive drug therapy.

TL;DR: Preventive application of NIV combined with assisted coughing after extubation provides a clinically important advantage to patients with NMD by averting the need for reintubation or tracheostomy and shortening their stay in the RICU; its use should be included in the routine approach to patientswith NMD at high risk for postextubation respiratory failure.

TL;DR: Patients with 2009 influenza A(H1N1) and respiratory failure requiring mechanical ventilation often present with clinical criteria of acute respiratory distress syndrome and shock and Mortality is high and is primarily due to refractory hypoxia.

TL;DR: The early detection of sepsis promoted early treatment, reducing in-hospital mortality from severe sepsi/septic shock.

TL;DR: The early recognition of oxidative damage in these seriously ill patients and the usefulness of oxidative stress biomarkers to define a cut point for more successful therapeutic antioxidant interventions to be instituted would offer a new strategy to improve the outcome of critically ill children.

TL;DR: Most plasma M MPs and TIMPS were elevated in patients with severe sepsis, but only a limited subset of MMPs negatively correlated with disease severity, and recombinant activated protein C does not appear to directly alter MMP2, 9 activities.

TL;DR: A novel multi-modal hand hygiene system resulted in a reduction in VAP, suggesting provider hand contamination during patient care in the ICU is a modifiable risk factor for reducing ventilator associated pneumonias.

TL;DR: The result of this study supports the fact that organ failure and critical illness lead to a decline in serum zinc concentrations and that administration of zinc may be beneficial for critically ill patients.

TL;DR: The changing epidemiology of fungal infections and associated risk factors, resistance issues with commonly administered antifungal agents, and treatment options for IFIs are reviewed, with a focus on polyenes.

TL;DR: Adoption of these care bundles should rationalize VAP management practices and facilitate the development of consistent and guideline-compliant care processes.

TL;DR: Cardiac manifestations of AP relevant to clinical practice are highlighted, including hypovolemia and metabolic disturbances, which are common among the multiple organ system dysfunctions in severe AP.

TL;DR: Serial PCT measurements should be used in clinical practice to guide administration of appropriate antimicrobials and reflect the benefit or not of the administered antimicrobial therapy.