Showing papers in "Journal of Inorganic Biochemistry in 2022"

TL;DR: In this article, the role of copper in cancer, the effects of copper-complexes on tumor cell death mechanisms, and point to the new copper complexes applicable as drugs, suggesting that they may represent at least one component of a multi-action combination in cancer therapy.

TL;DR: In this article , the role of copper in cancer, the effects of copper-complexes on tumor cell death mechanisms, and point to the new copper complexes applicable as drugs, suggesting that they may represent at least one component of a multi-action combination in cancer therapy.

TL;DR: In this article , the authors showed that Cd exposure induced renal anatomical and histopathological injuries, including renal nephrotoxicity and detoxification response, in chicken's kidneys, at doses of 35, 70, and 140 mg/kg with feed for 90 days.

TL;DR: In this article , the iridium (III) complexes were characterized by high-resolution mass spectrometry (HRMS), 1H NMR and 13C NMR, and the newly synthesized complexes showed high antiproliferative activity against B16 cells.

TL;DR: In this article , five (thio)semicarbazones with different donor sets were selected and their behavior in aqueous solution, the stability of their copper(II) complexes in addition to their cytotoxicity, DNA-binding, DNA cleavage ability and inhibition of topoisomerase IIα were investigated and compared.

TL;DR: In this paper , a facile, environmentally friendly and cost-effective method was adopted to green synthesized silver nanoparticles via the extract of Dioscorea cirrhosa tuber (DCTE-Ag NPs).

TL;DR: In this article , the authors provide insight into the size, shape, surface properties, and co-encapsulation of various metal nanoparticles in managing multidrug-resistant bacterial infections.

TL;DR: A review of the latest achievements in this field with particular attention to the identification of the target proteins responsible for such activity is provided in this paper , where the authors highlight the importance of cell migration, invasion, and adhesion in metastasis.

TL;DR: In this paper , a new ligand TFBIP (TFBIP = 2-(4'-trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-imidazo[4,5-f][1,10]phenanthroline) and its three iridium (III) complexes were synthesized and characterized.

TL;DR: A review of the latest achievements in this field with particular attention to the identification of the target proteins responsible for such activity is provided in this paper, where the authors highlight the importance of cell migration, invasion, and adhesion in metastasis.

TL;DR: In this paper, the effect of copper-II-chelation by luteolin on DNA damage via the Cu-Fenton reaction was studied, and the effect was more pronounced compared to quercetin and kaempferol.

TL;DR: In this article , ligand IPP (IPP = 4H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)-N,N-diphenylaniline) and its three Ru(II) complexes were synthesized and characterized.

TL;DR: In this article , the effect of copper-II-chelation by luteolin on DNA damage via the Cu-Fenton reaction was studied, and the effect was more pronounced compared to quercetin and kaempferol.

TL;DR: In this paper , the authors explored the molecular mechanism underlying the protective effects of sodium selenite (Na2SeO3) against HgCl2-induced neurotoxicity.

TL;DR: In this article , the effects of decavanadate and metformin-decavadate on Ca2+-ATPase activity in sarcoplasmic reticulum vesicles from rabbit skeletal muscles and on cell signaling events and viability in human melanoma cells were compared.

TL;DR: In this paper, the air and water stability and biological potential of simple metal-carbamates were evaluated in a screening study aimed to assess for the first time the air-and water-stability and the biological potential, and complexes [Ag(O2CNEt2)] (13-Ag) and [Au(O 2CNMe2)(PPh3)] (14-Au) resulted substantially stable and exhibited a potent in vitro cytotoxicity.

TL;DR: Zhang et al. as mentioned in this paper found that Se deficiency can cause immune organ damage by regulating the expression of microRNA in broilers and inferred miRNA (miR-144-3p) and target gene Stanniocalcin 1 (STC1) that may regulate PI3K/AKT pathway through biological analysis system, and further predicted and determined the targeting relationship between them through dual luciferase.

TL;DR: Zhang et al. as discussed by the authors found that Se deficiency can cause immune organ damage by regulating the expression of microRNA in broilers and inferred miRNA (miR-144-3p) and target gene Stanniocalcin 1 (STC1) that may regulate PI3K/AKT pathway through biological analysis system, and further predicted and determined the targeting relationship between them through dual luciferase.

TL;DR: In this paper , the air and water stability and biological potential of simple metal-carbamates were assessed for the first time, and complexes [Ag(O2CNEt2)] (13-Ag) and [Au (O2CNMe2)(PPh3)] (14-Au) resulted substantially stable in aqueous media and exhibited a potent in vitro cytotoxicity, especially 13-Ag revealed a significant selectivity against the A549 lung adenocarcinoma and the A2780 ovarian cancer cell lines with respect to the noncancerous HEK293 cell line.

TL;DR: In this paper , five Zn(II) complexes with 3,5-dichloro-salicylaldehyde (3, 5-diCl-saloH) in the absence or presence of N,N'-donor co-ligands (2,2'-bipyridine, 1,10-phenanthroline, 2,9-dimethyl-1,10phenanthusline, or 2,2"-biprylhydrazyl) were synthesized and formulated as [Zn(3,5)-diCl]-salo)2(CH3OH)2] (1)

TL;DR: In this paper, neutral zinc(II) complexes of 3,5-dibromo-salicyladehyde were synthesized in the presence of nitrogen-donor co-ligands.

TL;DR: In this article , a ruthenium (II) polypyridyl complex was combined with Taxol (Δ-Ru1 & Taxol) for cervical cancer HeLa cell line (HeLa/Taxol).

TL;DR: In this paper , neutral zinc(II) complexes of 3,5-dibromo-salicyladehyde were synthesized in the presence of nitrogen-donor co-ligands.

TL;DR: The potential of IONs as a magnetic nano-formulation for smart drug delivery has been confirmed by the release of both metallodrugs under conditions relevant to cancer cytosol as mentioned in this paper .

TL;DR: In this article , a tetra-substituted phthalonitrile (diethyl 2-(2-chloro-4,5-dicyano-3,6-bis(hexyloxy)phenyl)malonate) bearing three different substituents was synthesized and characterized.

TL;DR: In this paper , the diorganotin(IV) complexes were synthesized by microwave reaction with arylformylhydrazine, pyruvic acid, and corresponding R2SnCl2.

TL;DR: In this article , two new iridium(III) complexes [Ir(ppy)2(CBIP)](PF6) (ppy = 2-phenylpyridine, CBIP = 2-(4'-chloro-(1,1'-biphenyl))-1H-imidazo[4,5-f][1,10]phenanthroline) (Ir1) and [Irpiq)2 (CBIP) (PF6), respectively, were synthesized and characterized.

TL;DR: In this article , two new μ2-oxido bridged divanadium (V) complexes, [VV2O3(L1,2)2] (1 and 2) have been synthesized using bi-negative tridentate ONO-donor ligands, H2L 1,2 (H2L1 = 4-tert-butyl-2-[[[3,5-di-tertert]-butyl]-2-hydroxyphenyl]methylene]amino]phenol and H 2L2 = 5-bromo-2]-

TL;DR: In this paper , one oxidomethoxidovanadium (V) [VVO(L)(OMe)] (1) and two mixed-ligand oxidovanadium(IV), [VIVO(L),phen] (2), and [VVO(Bipy) [bipy], (3) complexes have been synthesized using a tridentate bi-negative ONS donor dithiocarbazate as main ligand.

TL;DR: Zhang et al. as mentioned in this paper showed that elevated intracellular zinc concentration directly inhibits SARS-CoV-2 replication and suggest the potential benefits to use the zinc supplements for coronavirus disease 2019 (COVID-19) treatment.