Showing papers in "Journal of Neuroscience Methods in 2003"

TL;DR: In this research, discrete Daubechies and harmonic wavelets are investigated for analysis of epileptic EEG records and the capability of this mathematical microscope to analyze different scales of neural rhythms is shown to be a powerful tool for investigating small-scale oscillations of the brain signals.

TL;DR: Simulations demonstrate the usefulness of the time-variant Granger causality for detecting dynamic causal relations within time intervals of less than 100 ms.

TL;DR: An adaptation of a new expectation-maximization based competitive mixture decomposition algorithm is introduced and it is shown that it efficiently and reliably performs mixture decompositions of t-distributions.

TL;DR: The present results demonstrate the effectiveness of the new dDTF method and indicate that the dD TF method can be used to obtain the reliable patterns of connections between various brain structures.

TL;DR: Arguments based on single motor unit action potential (AP) trains are used to demonstrate that rectification effectively enhances the firing rate information of the signal and grouped firing rate frequencies prior to coherency analyses may further aid interpretation of significant cortico-muscular coherence findings.

TL;DR: This work systematically explored temporal fixation thresholds below 200 ms, using biologically relevant (human face) and abstract (complex geometric) stimuli and found the median was a less biased and more robust measure of central tendency than the mean.

TL;DR: The preparation of a rat template intended for use together with SPM to enable spatial normalisation of individual rat brains to facilitate reporting results in co-ordinates directly corresponding to the Paxinos co-ordinate system is described.

TL;DR: An information-theoretic test for general Granger causality is used to identify couplings and information transport between different brain areas during epileptic activities and provides a useful and model free test to characterize interactions in intracranial electroencephalography signals.

TL;DR: The theoretical basis and the underlying assumptions of MPFA are described, illustrating how a simplified multinomial model can be used to estimate mean quantal parameters at synapses where quantal size and release probability are nonuniform.

TL;DR: It is concluded that low intensity direct electric stimulation enhances nerve regeneration following a controlled nerve crush injury and increases blood supply by increasing number and diameter of vasa nervorum.

TL;DR: Variants of two sensorimotor tasks, the gridwalk and spontaneous forelimb use (SFL) tasks, were assessed for their ability to reveal behavioral dysfunction following traumatic brain injury in mice.

TL;DR: It is concluded that z-axis distortion varies significantly between embedding and sectioning methods, and that vibratome-, methacrylate- and paraffin sections can result in grossly biased estimates.

TL;DR: It is shown for the first time in vivo that there is release of copper by synaptosomes upon depolarisation and this finding was validated with a completely independent analytical approach based on ICP-MS (inductively-coupled-plasma mass-spectrometry).

TL;DR: A simple and inexpensive test that measures long-term behavioral deficits in mice treated with moderate doses of MPTP, which is significantly correlated with the loss of striatal dopamine and immunoreactivity of the dopamine transporter, vesicular monoamine transporter and tyrosine hydroxylase is described.

TL;DR: The macrosphere MCAO model provides reproducible focal cerebral ischemia, similar to the established suture technique, but avoids hypothalamic damage and hyperthermia and may be more appropriate for the preclinical evaluation of neuroprotective therapies.

TL;DR: The protocol described here provides an effective and reliable method to isolate pure cerebral endothelium from adult mouse brain that should offer a useful tool for studying the role of altered vascular biology in mice with genetically manipulated brain disorders.

TL;DR: Subdermal injection of FCA around the tibiotarsal joint of the mouse provides a useful model to investigate inflammatory-induced nociceptive behaviours, which can be used in genetically manipulated mouse lines that use C57Bl6 as a background strain.

TL;DR: Modification of electrophysiology techniques for SCE leads to very simple and efficient transfection of neurons in organotypic rat hippocampus and mouse cortex slice cultures and demonstrates that the method can be employed to analyze subcellular trafficking and targeting in single living neurons.

TL;DR: This paper shows how to achieve a white display by adding video amplifiers to duplicate the monochrome signal to drive all three guns of any color monitor using conventional, easy-to-get equipment.

TL;DR: The present work presents a methodology that allows for automatic categorical pattern recognition of the behavioral strategies performed in the Morris water maze, and offers a methodology to computationally reproduce the human categorization of behaviors in the MWM.

TL;DR: The first successful implementation of optical coherence tomography (OCT) at around 30 microm depth resolution is reported to investigate cortical functions of a cat brain in vivo, named functional OCT (fOCT).

TL;DR: Subdural electrodes show promising results for recording visual and electrical evoked responses (EERs) and thus for evaluation of the retinal prosthesis in dogs under two methods of anesthesia-halothane and propofol.

TL;DR: The film coated on silicone rubber is biocompatible for cerebellar neurons with active viability, as shown by lactate dehydrogenase (LDH) assay and fluorescence cellular metabolism observations, demonstrating that LbL self-assembly provides an effective approach to apply films with nanometer thickness to silicone rubber.

TL;DR: A new multivariable closed-loop identification technique for estimating the dynamic compliance of the multijoint human arm during posture maintenance is presented and it is concluded that the identification technique is accurate, even for short observation periods and severe noise.

TL;DR: The manufacturing changes described in this study enable the construction of more mechanically robust polyLIFEs, which should provide greater success when chronically implanted in peripheral nerves.

TL;DR: The efficacy of the GT for the quantitative assessment of motor function recovery is re-appraised and a modified device for its carrying out is described and the rationale for the employment of the median nerve model as an alternative to the sciatic nerve model is critically discussed.

TL;DR: The new method, which is an expansion of the CUSUM analysis, is compared and contrasted with the more common threshold-crossing method in two different muscles: masseter and first dorsal interosseous (FDI), in experiments utilizing both mechanical and electrical stimulation.

TL;DR: A new skin attachment technique is developed that yields firm electrode fixation without requiring an acrylic housing and improves measurement selectivity and makes possible the non-invasive observation of multiple facial muscles with a minimum of obstruction.

TL;DR: A method to purify p75 low affinity nerve growth factor receptor (p75LNGFr) expressing Schwann cells from peripheral nerve biopsies in adult rats using magnetic-activated cell separation (MACS) is reported, representing an effective and fast means to generate autologous Schwann Cells for clinical transplantation strategies aiming for axon repair and remyelination.

TL;DR: Observations show that a period of anodal DC stimulation preceding aperiod of ulnar nerve stimulation resulted in significant and persistent elevations in cortical excitability.