Showing papers in "Respiratory Medicine in 2005"

TL;DR: These three shortened versions of the Asthma Control Questionnaire can be used in large clinical trials without loss of validity or change in interpretation.

TL;DR: In this paper, the authors compare the OLD population recruited from GP's and specialist outpatient clinics, respectively, and conclude that "evidence based" treatment decisions for OLD are based on studies which include a very small and highly selected fraction of this patient population.

TL;DR: Results suggest that psychiatric disorders are prevalent among asthmatics and are associated with worse asthma control and quality of life.

TL;DR: Evidence that supports the concept that COPD is a multicomponent disease is presented and the effects of currently available therapeutic options, including long- acting anticholinergics and long-acting beta2-agonist/inhaled corticosteroid combination therapies, upon each of these components is reviewed.

TL;DR: The evidence for applying a weaning process and physiotherapy techniques in these patients has been described according to their individual rationale and efficacy, and there are only strong recommendations concerning the evidence-based strategies to speed weaning.

TL;DR: Nebulised hypertonic saline can be used safely and effectively as an adjunct to physiotherapy in selected patients and a long-term prospective trial is now indicated to determine its effectiveness on long- term infection rate, quality of life and lung function.

TL;DR: Despite incentives to perform spirometry in general practice, lack of adequate training in use and interpretation suggests use is confounded and the diagnosis of COPD is likely to be made on imprecise clinical grounds.

TL;DR: In this paper, the authors used exhaled breath condensate (EBC) to investigate cytokine patterns in stable chronic obstructive pulmonary disease (COPD), exacerbated COPD, smokers without apparent COPD and healthy volunteers.

TL;DR: The present study compared MMP profiles in the airways of non-smokers, non-symptomatic cigarette smokers, and patients with COPD or asthma and found that the MMP profile in COPD differs to that in asthma and cigarette smokers.

TL;DR: The recent change in classification from short- and long-acting beta2-agonists to rapid-acting and/or long- acting agents reflects the ongoing evolution of beta2 -agonist therapy.

TL;DR: The impact of the systemic manifestations of COPD is substantial, and although many attempts have been made to elucidate the mechanisms underlying these manifestations, there are important questions, which remain to be answered.

TL;DR: This study confirms a previous report that adherence profiles of fluticasone and salmeterol in a single inhaler are significantly better when compared to the controller regimens of flicosteroids in separate inhalers, flutic asone and montelukast, or fluticASone alone and similar to montelUKast alone.

TL;DR: The use of antibiotics for acute otitis media, sore throat and streptococcal tonsillitis, common cold and acute purulent rhinitis, and acute maxillary sinusitis seems to be discretionary rather than prohibited or mandatory, at least for non-severe cases.

TL;DR: Dyspnoea was the most important factor determining HRQoL in IPF, and the types of other variables that correlated with the HRQeL inIPF patients were different from those in COPD.

TL;DR: In some patients withNocturnal asthma, OSAS may be responsible disease for nocturnal symptoms without amelioration in PFT abnormalities, and continuous positive airway pressure (CPAP) therapy to improve nighttime symptoms in asthmatic patients with OSAS is investigated.

TL;DR: Men who are predisposed to develop diabetes have decreased lung function many years prior to the diagnosis, compared with men who do not develop diabetes, and this decrement in lung function remains after the development of diabetes.

TL;DR: Early rehabilitation via a home from hospital programme improved exercise tolerance, muscle strength, dyspnea scores, quality of life in COPD patients and reduced the number of subsequent exacerbations.

TL;DR: Body composition, measured by bioelectrical impedance and presented as FFMI, is an independent predictor of mortality in COPD patients, according to a study of patients included in a 1-year multidisciplinary rehabilitation program.

TL;DR: Monitoring patients with moderate to severe COPD during an exacerbation suggested that the markers H2O2 in exhaled air, IL-8 and sICAM in serum are suitable markers in monitoring exacerbated COPD.

TL;DR: Cardiopulmonary exercise test parameters and the 6MWTD were associated with the risk of death and measures during exercise may be useful for determination of prognosis and for prioritizing patients with diffuse parenchymal lung disease for lung transplantation.

TL;DR: Results indicate that targeted resistive or threshold IMT was associated with significant improvements in some outcomes of inspiratory muscle strength and endurance and endurance, exercise capacity, dyspnea and quality of life for adults with chronic obstructive pulmonary disease.

TL;DR: S. pneumoniae was the most common etiology agent in adult patients hospitalized due to CAP in Taiwan and the spectrum of other major pathogens was similar to studies conducted elsewhere in the world.

TL;DR: The findings are in line with emerging evidence that the spectrum of interstitial damage caused by smoke includes not only Langerhans cell hystiocytosis, respiratory bronchiolitis or desquamative interstitial pneumonia but also advanced usual interstitial pneumonitis as well.

TL;DR: It is concluded that the isolated elevation of hemidiaphragm on chest radiograph is of little value in the diagnosis of unilateral hemido-phrenic nerve stimulation studies, though the condition is unlikely if diaphagm elevation is absent.

TL;DR: The increased risk of asthma in young Swedish men with obesity has remained unchanged over a period of three decades, and obesity was associated with a slightly increased risk for all three conditions.

TL;DR: In difficult asthmatics, there is a high prevalence of undiagnosed psychiatric morbidity, with depression being particularly prevalent, and a simple screening questionnaire such as HADS has a high false positive rate when compared to psychiatric interview, but may be useful in excluding depressive illness.

TL;DR: It is concluded that chronic obstructive pulmonary disease patients have a lower HRR than healthy subjects, and have a worse prognosis when presenting abnormal HRR.

TL;DR: Serum YKL-40 may be a novel biomarker of Sarcoid disease activity and ongoing fibrosis in patients with pulmonary sarcoidosis.

TL;DR: There was a strong positive correlation between lead and cadmium concentrations in both fine dust and coarse dust and a probable explanation is a direct inhalation of side-stream smoke containing heavy metals and/ or an increased pulmonary uptake, due to a small airways disease in children with asthma.

TL;DR: It is indicated that purulent sputum is strongly associated with bacterial growth in COPD exacerbations and functional impairment (FEV1) orientates as to the infectious etiology of exacerbations.