Showing papers in "The American Journal of Medicine in 1993"

TL;DR: Pneumonias occurring in ventilated patients, especially those due to Pseudomonas or Acinetobacter species, are associated with considerable mortality in excess of that resulting from the underlying disease alone, and significantly prolong the length of stay in the intensive care unit.

TL;DR: The risk for bleeding can be estimated in an individual patient, giving the primary physician a quantitative basis for weighing the risks and benefits of therapy and for optimizing patient management.

TL;DR: Indications for antibiotic therapy for eradication of colonization and treatment of infection are reviewed, and recommendations for handling an outbreak, surveillance, and culturing of patients are presented based on the known epidemiology.

TL;DR: The increased atherogenic risk associated with the pattern B phenotype may result in part from increased concentrations of lipoprotein subpopulations that are relatively susceptible to oxidative modification.

TL;DR: Vertebral compression fractures are associated with significant performance impairments in physical, functional, and psychosocial domains in older women.

TL;DR: Midodrine is an effective and well-tolerated treatment for moderate-to-severe orthostatic hypotension associated with autonomic failure and the overall side effects were mainly mild to moderate.

TL;DR: Carefully designed asthma education programs for adults can improve patients' understanding of their condition and its treatment and increase their motivation and confidence that the condition can be controlled, thereby increasing their adherence to the treatment regimen and management of symptoms and, in turn, improving control of symptoms.

TL;DR: Three years of intermittent cyclic etidronate therapy produced significant increases in spinal and hip bone density, with a significant reduction in vertebral fracture rates in patients at higher fracture risk.

TL;DR: The results suggest that AFI measured by ultrasonography may be a new indicator of visceral fat deposition, and may reflect metabolic disorders such as lipid metabolism and glucose metabolism disorders.

TL;DR: Clinically significant tumor lysis is a rare occurrence in patients with lymphoma when they are receiving allopurinol, however, patients with all types of moderate to high-grade non-Hodgkin's lymphoma are at increased risk for metabolic complications after chemotherapy and should be closely monitored.

TL;DR: Determining the clinical group, autoantibody status, and time from disease onset to diagnosis of patients with myositis provides useful information in predicting clinical responses to therapy, and these factors should be considered in designing future therapeutic trials.

TL;DR: Overweight postmenopausal women benefit from addition of combined aerobic and anaerobic exercise to an energy-restrictive diet, and the diet itself has a positive effect on cardiovascular risk factors.

TL;DR: There was a significant cross-sectional association between past TWAR infection and asymptomatic atherosclerosis and this organism may be a contributor to the pathogenesis of Atherosclerosis.

TL;DR: Screening for drugs that preferentially inhibit PGHS-2 may allow identification of NSAIDs that reduce inflammation, but spare renal and gastric prostaglandin synthesis, thus reducing the untoward side effects commonly associated with most NSAIDs.

TL;DR: A systematic preoperative evaluation in conjunction with fluid and tissue analysis following subxiphoid pericardiotomy yields a diagnosis in the majority of patients with largePericardial effusions.

TL;DR: CSS is an underdiagnosed cause of dizziness, falls, and syncope in the elderly and has clinical characteristics similar to those of the cardioinhibitory and mixed subtypes.

TL;DR: Treatment with standardized garlic 900 mg/d produced a significantly greater reduction in serum TC and LDL-C than placebo, and the garlic formulation was well tolerated without any odor problems.

TL;DR: A single-dose infusion of 60 to 90 mg of pamidronate was highly effective and well tolerated and normalized corrected serum calcium in nearly all patients with hypercalcemia of malignancy.

TL;DR: It is indicated that low levels of cholesterol are prevalent during the early stages of HIV-1 infection and associated with specific alterations in immune function, suggesting that hypocholesterolemia may be a useful marker of disease progression.

TL;DR: It is suggested that aspergillosis is an important life-threatening condition in the advanced stage of AIDS and requires an early diagnosis with BAL fluid culture and careful therapeutic evaluation.

TL;DR: Patients with CFS did not demonstrate a specific response to immunologic and/or psychologic therapy, and the improvement recorded in the group as a whole may reflect both nonspecific treatment effects and a propensity to remission in the natural history of this disorder.

TL;DR: A 1-year follow-up after parathyroidectomy (and restoration of normocalcemia) discloses regression of hypertrophy, while calcifications persist without evidence of progression, show a high incidence of left ventricular hyperTrophy, calcific deposits in the myocardium, and/or aortic and mitral valve calcification in patients with primary hyperparathyroidism.

TL;DR: Osteopenia and vertebral fractures are common in patients after cardiac transplantation and the presence of elevated osteocalcin levels suggests that the pathogenesis of the osteoporosis in these patients differs from that of glucocorticoid-induced osteoporeosis.

TL;DR: Mupirocin ointment is effective at decreasing colonization with MRSA, however, constant surveillance was required to identify patients colonized at admission or experiencing recurrence of MRSA during maintenance treatment, and should be saved for use in outbreak situations and not used over the long term in facilities with endemic MRSA colonization.

TL;DR: Labetalol reverses the cocaine- induced rise in mean arterial pressure, but does not alleviate cocaine-induced coronary vasoconstriction.

TL;DR: This pneumonia-specific prognostic index, which performs exceptionally well in classifying low-risk patients, may help physicians identify patients with community-acquired pneumonia who could safely be managed in the ambulatory setting, or if hospitalized, the patients that could be treated with abbreviated inpatient care.

TL;DR: A number of promising immunologic approaches for cancer diagnosis, detection, and therapy have made important progress in recent years.

TL;DR: Co-administration of pravastatin and gemfibrozil combined the specific effects of the two drugs on lipoprotein concentrations and ratios; the combination may be useful in selected cases of combined hyperlipidemia; however, the routine use of combination therapy is not advisable.

TL;DR: Spontaneous recovery of the HPA axis is usual for patients who are taking prednisone at daily doses of 5 mg or less, and return of normal HPAaxis function can be achieved without alternate-day therapy in patients whose disease allows tapering to daily prednisones of 5mg or less.