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2010 National and State Costs of Excessive Alcohol Consumption
TLDR
For example, this paper estimated that excessive alcohol use cost the U.S. $223.5 billion in 2006, and more current estimates are needed to help inform the planning of prevention strategies.Abstract:
Excessive alcohol use cost the U.S. $223.5 billion in 2006. Given economic shifts in the U.S. since 2006, more-current estimates are needed to help inform the planning of prevention strategies.read more
Citations
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Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder
Elizabeth M. Burnette,Steven J. Nieto,Erica N. Grodin,Lindsay R. Meredith,Brian Hurley,Karen Miotto,Artha Gillis,Lara A. Ray +7 more
TL;DR: A qualitative literature review of repurposed and novel pharmacotherapies for the treatment of alcohol use disorder is presented in this paper , where the authors discuss the efficacy, mechanism of action, and tolerability of these drugs from a clinical perspective.
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Defining Recovery From Alcohol Use Disorder: Development of an NIAAA Research Definition.
TL;DR: The authors present a newly developed National Institute on Alcohol Abuse and Alcoholism (NIAAA) definition of recovery from DSM-5 AUD based on qualitative feedback from key recovery stakeholders, which views recovery as both a process of behavioral change and an outcome and incorporates two key components of recovery.
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The Economic Burden of Posttraumatic Stress Disorder in the United States From a Societal Perspective.
Lori L. Davis,Jeffrey Schein,Martin Cloutier,Patrick Gagnon-Sanschagrin,J. Maitland,Annette L. Urganus,Annie Guerin,Patrick Lefebvre,Christy R. Houle +8 more
TL;DR: The economic burden of PTSD goes beyond direct health care costs and has been found to rival costs for other costly mental health conditions and may need to be reduced to reduce the large clinical and economic burden.
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Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
John Peyton Bohnsack,Huaibo Zhang,Gabriela M Wandling,Donghong He,Evan J. Kyzar,Amy W. Lasek,Subhash C. Pandey +6 more
TL;DR: It is shown that dCas9-P300 increases histone acetylation at the Arc SARE and normalizes deficits in Arc expression, leading to attenuation of adult anxiety and excessive alcohol drinking in a rat model of adolescent alcohol exposure.
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Consideration of sex and gender differences in addiction medication response
TL;DR: In this paper , the authors highlight how sex and gender have been considered (or not) in medication trials for substance use disorders and provide direction to the field to advance medication development that is consistent with current NIH "sex as a biological variable" (SABV) policy.
References
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Prevalence of 12-Month Alcohol Use, High-Risk Drinking, and DSM-IV Alcohol Use Disorder in the United States, 2001-2002 to 2012-2013: Results From the National Epidemiologic Survey on Alcohol and Related Conditions
Bridget F. Grant,S. Patricia Chou,Tulshi D. Saha,Roger P. Pickering,Bradley T. Kerridge,W. June Ruan,Boji Huang,Jeesun Jung,Haitao Zhang,Amy Z. Fan,Deborah S. Hasin,Deborah S. Hasin +11 more
TL;DR: Increases in alcohol use, high-risk drinking, and DSM-IV AUD in the US population and among subgroups, especially women, older adults, racial/ethnic minorities, and the socioeconomically disadvantaged, constitute a public health crisis.
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Economic Costs of Excessive Alcohol Consumption in the U.S., 2006
TL;DR: In this article, the authors followed U.S. Public Health Service Guidelines to assess the economic cost of excessive alcohol consumption in 2006 and found that excessive drinking causes premature death (average of 79,000 deaths annually), increased disease and injury; property damage from fire and motor vehicle crashes; alcoholrelated crime; and lost productivity.
Journal Article
Global strategy to reduce the harmful use of alcohol
Rajat Ray,PK Anish +1 more
TL;DR: The concept of the harmful use of alcohol is broad and encompasses the drinking that causes detrimental health and social consequences for the drinker, the people around the Drinker and society at large, as well as the patterns of drinking that are associated with increased risk of adverse health outcomes.
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U.S. Preventive Services Task Force
TL;DR: The U.S. Preventive Services Task Force is evaluating the scientific basis of various preventive services to develop age- and sex-specific recommendations concerning their appropriate use in clinical settings to facilitate practitioners' incorporation of efficacious preventive interventions into clinical practice.
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Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States.
TL;DR: Excessive drinking was responsible for 1 in 10 deaths among working-age adults in the United States and AAD rates vary across states, but excessive drinking remains a leading cause of premature mortality nationwide.